[go: up one dir, main page]

Udukala, 2014 - Google Patents

Protease assays for cancer diagnostics

Udukala, 2014

View PDF
Document ID
4938606676541572833
Author
Udukala D
Publication year

External Links

Snippet

Numerous proteases are known to be necessary for cancer development and progression including Matrix Metalloproteinases (MMPs), Tissue Serine Proteases, and Cathepsins. The goal of this research is to develop a Fe/Fe3O4 nanoparticle-based system for clinical …
Continue reading at krex.k-state.edu (PDF) (other versions)

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay
    • G01N33/574Immunoassay; Biospecific binding assay for cancer
    • G01N33/57407Specifically defined cancers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/48Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

Similar Documents

Publication Publication Date Title
Li et al. Activity‐based smart AIEgens for detection, bioimaging, and therapeutics: recent progress and outlook
Huang et al. Activatable molecular probes for second near‐infrared fluorescence, chemiluminescence, and photoacoustic imaging
Zhao et al. Targeted contrast agents and activatable probes for photoacoustic imaging of cancer
Li et al. Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy
Blau et al. Chemiluminescent probes in cancer biology
Tian et al. Fluorescent small organic probes for biosensing
Xiao et al. Aminopeptidase‐N‐activated theranostic prodrug for NIR tracking of local tumor chemotherapy
He et al. Near-infrared fluorescent macromolecular reporters for real-time imaging and urinalysis of cancer immunotherapy
Kawatani et al. Fluorescence detection of prostate cancer by an activatable fluorescence probe for PSMA carboxypeptidase activity
Li et al. Molecular engineering of organic-based agents for in situ bioimaging and phototherapeutics
Luo et al. Activatable Near‐Infrared Probe for Fluorescence Imaging of γ‐Glutamyl Transpeptidase in Tumor Cells and In Vivo
Tian et al. Near-infrared fluorescent probes for hypoxia detection via joint regulated enzymes: design, synthesis, and application in living cells and mice
Knapinska et al. Chemical biology for understanding matrix metalloproteinase function
Zeng et al. Ratiometric imaging of MMP‐2 activity facilitates tumor detection using activatable near‐infrared fluorescent semiconducting polymer nanoparticles
McIntyre et al. Development of a novel fluorogenic proteolytic beacon for in vivo detection and imaging of tumour-associated matrix metalloproteinase-7 activity
Ma et al. “Smart” nanoprobes for visualization of tumor microenvironments
Li et al. Activatable near‐infrared versatile fluorescent and chemiluminescent dyes based on the dicyanomethylene‐4H‐pyran scaffold: from design to imaging and theranostics
Liu et al. Precipitated fluorophore-based molecular probe for in situ imaging of aminopeptidase N in living cells and tumors
Fujii et al. In vivo imaging of intraperitoneally disseminated tumors in model mice by using activatable fluorescent small-molecular probes for activity of cathepsins
US20120157824A1 (en) Mri and optical assays for proteases
Wang et al. Nanoplatforms for highly sensitive fluorescence detection of cancer-related proteases
Ogata et al. Activatable near-infrared fluorescence imaging using PEGylated bacteriochlorin-based chlorin and BODIPY-dyads as probes for detecting cancer
Wang et al. Stimuli‐responsive linkers and their application in molecular imaging
Zhang et al. Recent progress in the development of small-molecule double-locked logic gate fluorescence probes
Schleyer et al. Molecular probes for selective detection of cysteine cathepsins