BATTY - Google Patents
Role of Casein Kinase 1 of Plasmodium falciparum in parasite biology and as a target for novel anti-malarial drugsBATTY
View PDF- Document ID
- 1145594285598171574
- Author
- BATTY M
External Links
Snippet
Post-translational modifications (PTMs) are essential biochemical switches that regulate protein interactions and many cellular functions. Dysregulation of this essential modification contributes to the establishment of diseases such as cancer. A PTM of major importance is …
- 244000045947 parasites 0 title abstract description 272
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/569—Immunoassay; Biospecific binding assay for micro-organisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Hybridisation probes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Kumar et al. | PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum | |
| Billker et al. | Calcium and a calcium-dependent protein kinase regulate gamete formation and mosquito transmission in a malaria parasite | |
| McCoy et al. | Tg CDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells | |
| Fougere et al. | Variant exported blood-stage proteins encoded by Plasmodium multigene families are expressed in liver stages where they are exported into the parasitophorous vacuole | |
| Wichers et al. | Dissecting the gene expression, localization, membrane topology, and function of the Plasmodium falciparum STEVOR protein family | |
| Patzewitz et al. | An ancient protein phosphatase, SHLP1, is critical to microneme development in Plasmodium ookinetes and parasite transmission | |
| Bertolini et al. | MICU1 and MICU2 play an essential role in mitochondrial Ca2+ uptake, growth, and infectivity of the human pathogen Trypanosoma cruzi | |
| van Ooij et al. | Identification of a Plasmodium falciparum phospholipid transfer protein | |
| Faria et al. | Disclosing the essentiality of ribose-5-phosphate isomerase B in Trypanosomatids | |
| Baker | Cyclic nucleotide signalling in malaria parasites | |
| Chiurillo et al. | Functional analysis and importance for host cell infection of the Ca2+-conducting subunits of the mitochondrial calcium uniporter of Trypanosoma cruzi | |
| Deligianni et al. | Essential role of Plasmodium perforin-like protein 4 in ookinete midgut passage | |
| Bertschi et al. | Malaria parasites possess a telomere repeat-binding protein that shares ancestry with transcription factor IIIA | |
| Schoijet et al. | Defining the role of a FYVE domain in the localization and activity of a cAMP phosphodiesterase implicated in osmoregulation in Trypanosoma cruzi | |
| Ramaprasad et al. | A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite | |
| Miller et al. | Entamoeba histolytica develops resistance to complement deposition and lysis after acquisition of human complement-regulatory proteins through trogocytosis | |
| Possenti et al. | Functional characterization of the thrombospondin-related paralogous proteins rhoptry discharge factors 1 and 2 unveils phenotypic plasticity in Toxoplasma gondii rhoptry exocytosis | |
| Daher et al. | Regulation of protein phosphatase type 1 and cell cycle progression by PfLRR1, a novel leucine‐rich repeat protein of the human malaria parasite Plasmodium falciparum | |
| Kar et al. | The Immunologically Protective P-4 Antigen ofLeishmania Amastigotes: A DEVELOPMENTALLY REGULATED SINGLE STRAND-SPECIFIC NUCLEASE ASSOCIATED WITH THE ENDOPLASMIC RETICULUM | |
| Sethumadhavan et al. | Chromodomain protein interacts with H3K9me3 and controls RBC rosette formation by regulating the expression of a subset of RIFINs in the Malaria parasite | |
| Lee et al. | Merozoite surface protein 1 paralog is involved in the human erythrocyte invasion of a zoonotic malaria, Plasmodium knowlesi | |
| Lasonder et al. | cAMP-dependent signaling pathways as potential targets for inhibition of Plasmodium falciparum blood stages | |
| Basmaciyan et al. | A novel hydrolase with a pro-death activity from the protozoan parasite Leishmania major | |
| Nishi et al. | PbARID-associated chromatin remodeling events are essential for gametocyte development in Plasmodium | |
| Bandje et al. | Characterization of an A-kinase anchoring protein-like suggests an alternative way of PKA anchoring in Plasmodium falciparum |