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Leung et al., 1999 - Google Patents

Cytoskeletal regulation by Rho-p21 associated kinases: analysis of ROK and PAK function by plasmid microinjection

Leung et al., 1999

Document ID
11608837560531295821
Author
Leung T
Manser E
Lim L
Publication year
Publication venue
Microinjection

External Links

Snippet

Signaling from the Rho-p21 family of small GTP-binding proteins occurs through their interaction with a variety of target proteins, many of which specifically bind the p21s in their active GTP-bound form. Several of these effectors were originally identified in western …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/4702—Regulators; Modulating activity
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