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Umene et al., 1996 - Google Patents

Replication of herpes simplex virus type 1 DNA is inhibited in a temperature-sensitive mutant of BHK-21 cells lacking RCC1 (regulator of chromosome condensation) …

Umene et al., 1996

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Document ID
14061541489971811792
Author
Umene K
Nishimoto T
Publication year
Publication venue
Journal of general virology

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tsBN2, a temperature-sensitive (ts) growth mutant of the hamster cell line BHK-21, has a point mutation in the RCC1 (regulator of chromosome condensation) gene, and prematurely enters mitosis at 39.5° C, a nonpermissive temperature. In this mutant at 39.5° C infectious …
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