[go: up one dir, main page]

Ohno et al., 1997 - Google Patents

Polymorphonuclear leucocyte (PMN) inhibitory factor prevents PMN‐dependent endothelial cell injury by an anti‐adhesive mechanism

Ohno et al., 1997

Document ID
1574351581077516735
Author
Ohno S
Malik A
Publication year
Publication venue
Journal of cellular physiology

External Links

Snippet

Neutrophil inhibitory factor (NIF), a 41‐kD glycoprotein isolated from the canine hookworm, inhibits CD11b/CD18‐dependent neutrophil adhesion by binding to CD11b. We studied the effects of NIF on neutrophil‐dependent endothelial cell injury using bovine pulmonary …
Continue reading at onlinelibrary.wiley.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Similar Documents

Publication Publication Date Title
US6033665A (en) Compositions and methods for modulating leukocyte adhesion to brain endothelial cells
Yoshida et al. Anoxia/reoxygenation-induced neutrophil adherence to cultured endothelial cells
Sugama et al. Thrombin-induced expression of endothelial P-selectin and intercellular adhesion molecule-1: a mechanism for stabilizing neutrophil adhesion.
Cosimi et al. In vivo effects of monoclonal antibody to ICAM-1 (CD54) in nonhuman primates with renal allografts.
Wautier et al. Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy. Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats.
Mechtersheimer et al. Expression of the natural killer cell-associated antigens CD56 and CD57 in human neural and striated muscle cells and in their tumors
Kubes et al. A novel β1‐dependent adhesion pathway on neutrophils: a mechanism invoked by dihydrocytochalasin B or endothelial transmigration
Walsh et al. Human eosinophil, but not neutrophil, adherence to IL-1-stimulated human umbilical vascular endothelial cells is alpha 4 beta 1 (very late antigen-4) dependent
DK175491B1 (en) Use of ICAM-1 and its functional derivatives for the treatment of non-specific inflammation
Allavena et al. Molecules and structures involved in the adhesion of natural killer cells to vascular endothelium.
Issekutz In vivo blood monocyte migration to acute inflammatory reactions, IL-1 alpha, TNF-alpha, IFN-gamma, and C5a utilizes LFA-1, Mac-1, and VLA-4. The relative importance of each integrin.
Pelletier et al. Importance of endothelial VCAM-1 for inflammatory leukocytic infiltration in vivo
Luscinskas et al. Endothelial-leukocyte adhesion molecule-1-dependent and leukocyte (CD11/CD18)-dependent mechanisms contribute to polymorphonuclear leukocyte adhesion to cytokine-activated human vascular endothelium.
Price et al. In vivo inhibition of neutrophil function in the rabbit using monoclonal antibody to CD18.
Risso et al. Cytotoxicity and apoptosis mediated by two peptides of innate immunity
Mulligan et al. Roles of beta 2 integrins of rat neutrophils in complement-and oxygen radical-mediated acute inflammatory injury.
Gasic et al. Hydrogen peroxide pretreatment of perfused canine vessels induces ICAM-1 and CD18-dependent neutrophil adherence.
US5622700A (en) Method for treating a LFA-1-mediated disorder
Clarkson et al. CD16. Developmentally regulated IgG Fc receptors on cultured human monocytes.
Himmelfarb et al. Modulation of granulocyte LAM-1 and MAC-1 during dialysis—a prospective, randomized controlled trial
Ley Histamine can induce leukocyte rolling in rat mesenteric venules
Ala et al. Role of cell adhesion molecules in leukocyte recruitment in the liver and gut
Chuluyan et al. Domains 1 and 4 of vascular cell adhesion molecule-1 (CD106) both support very late activation antigen-4 (CD49d/CD29)-dependent monocyte transendothelial migration.
Bell et al. Expression of a protective intestinal immune response can be inhibited at three distinct sites by treatment with anti-alpha 4 integrin.
Humbría et al. Expression of L‐Selectin, CD43, and CD44 in Synovial Fluid Neutrophils from Patients with Inflammatory Joint Diseases