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Dalela et al., 2015 - Google Patents

pH-sensitive biocompatible nanoparticles of paclitaxel-conjugated poly (styrene-co-maleic acid) for anticancer drug delivery in solid tumors of syngeneic mice

Dalela et al., 2015

Document ID
4653238177625236317
Author
Dalela M
Shrivastav T
Kharbanda S
Singh H
Publication year
Publication venue
ACS applied materials & interfaces

External Links

Snippet

In the present study, we have synthesized poly (styrene-co-maleic anhydride), a biocompatible copolymer that was further conjugated with paclitaxel (PTX) via ester linkage and self-assembled to form poly (styrene-co-maleic acid)-paclitaxel (PSMAC–PTX) …
Continue reading at pubs.acs.org (other versions)

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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
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    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
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    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
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