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Chen et al., 1991 - Google Patents

Evaluation of a competitive NMDA antagonist (D‐CPPene) in feline focal cerebral ischemia

Chen et al., 1991

Document ID
4900650109150663931
Author
Chen M
Bullock R
Graham D
Frey P
Lowe D
McCulloch J
Publication year
Publication venue
Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society

External Links

Snippet

The effects of a competitive, N‐methyl‐D‐aspartate (NMDA) receptor antagonist, D (‐) E‐4‐ (3‐phosphonoprop‐2‐enyl)‐piperazine‐2‐carboxylic acid (D‐CPPene), on the volume of ischemic brain damage was assessed by quantitative histological study in 35 chloralose …
Continue reading at onlinelibrary.wiley.com (other versions)

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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