Heymans et al., 1985 - Google Patents
Structure-activity relationship in PAF-acether. 2. RAC-1-O-octadecyl-2-O-acetyl-3-O-[. gamma.-(dimethylamino) propyl] glycerolHeymans et al., 1985
- Document ID
- 5566746800755547144
- Author
- Heymans F
- Borrel M
- Broquet C
- Lefort J
- Godfroid J
- Publication year
- Publication venue
- Journal of medicinal chemistry
External Links
Snippet
Materials and Methods. A. Biological Methods. In Vitro Biological Assay. The platelet aggregating activity of PAF-acether and compounds 4 and 7 was performed on washed rabbit platelets as described previously. 7 Aggregations were assessed on 1.5 X 108 …
- 108010003541 Platelet Activating Factor 0 title abstract description 18
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P-C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA3224105A1 (en) | Nitrogen-containing heterocyclic compound, and preparation method therefor, intermediate thereof, and application thereof | |
| Borcherding et al. | Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 11. Molecular dissections of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase | |
| BR112015010019B1 (en) | SUBSTITUTED TRICYCLIC BENZIMIDAZOLS, THEIR USES, AND PHARMACEUTICAL COMPOSITION | |
| EP4071152A1 (en) | Spiro compound serving as erk inhibitor, and application thereof | |
| KR20080083044A (en) | Triterpenequinones and Triterpene Phenolic Derivatives and Uses thereof for the Treatment of Tumors and Parasitic Diseases | |
| Radulović et al. | Synthesis, spectral characterization, cytotoxicity and enzyme-inhibiting activity of new ferrocene–indole hybrids | |
| CN113825757B (en) | Substituted fused bicyclic derivatives, preparation method thereof and application thereof in medicine | |
| BR112018009995B1 (en) | CRYSTALLINE FORM, PHARMACEUTICAL COMPOSITION, AND USE OF CRYSTALLINE FORM | |
| WO2018084321A1 (en) | Novel compound useful for both egfr inhibition and tumor therapy | |
| Heymans et al. | Structure-activity relationship in PAF-acether. 2. RAC-1-O-octadecyl-2-O-acetyl-3-O-[. gamma.-(dimethylamino) propyl] glycerol | |
| JPH01503063A (en) | anti-inflammatory composition | |
| EP0390112B1 (en) | Selective adenosine receptor agents | |
| US20230062119A1 (en) | Use of biomarkers in identifying patients that will be responsive to treatment with a prmt5 inhibitor | |
| WO2019134573A1 (en) | Method for preparing deuterated diphenylaminopyrimidine compound and crystal form thereof | |
| Rios Morales et al. | Diastereoselective Synthesis of cycloSaligenyl‐Nucleosyl‐Phosphotriesters | |
| CN112279863A (en) | Conjugates of Hsp90 inhibitors and camptothecin derivatives and their preparation methods and applications | |
| CN113583026B (en) | Compounds containing condensed tricyclic structures | |
| TW553945B (en) | Triazolopurine derivatives, medicinal composition containing the derivatives, adenosine A3 receptor compatibilizing agent, and asthmatic remedy | |
| JP2024518447A (en) | PKC-θ modulators | |
| JP2023549273A (en) | Substituted pyrrolo[2,3-b]pyridine and pyrazolo[3,4-b]pyridine derivatives as protein kinase inhibitors | |
| JPS61112078A (en) | Substituted 7-oxomitosane | |
| CN108864114B (en) | Selectivity A2AReceptor antagonists | |
| US3751408A (en) | Imidazole-ribosyl cyclophosphate compounds and therapeutic compositions | |
| AU672226B2 (en) | 2-substituted adenosines with A-2 receptor affinity | |
| EP0390111B1 (en) | Selective adenosine receptor compounds |