[go: up one dir, main page]

Bruno et al., 1989 - Google Patents

On-column capillary flow cell utilizing optical waveguides for chromatographic applications

Bruno et al., 1989

Document ID
5792749140958786151
Author
Bruno A
Gassmann E
Pericles N
Anton K
Publication year
Publication venue
Analytical Chemistry

External Links

Snippet

INTRODUCTION The development of small optical detectors for microbore and capillary chromatographic techniques is gaining considerable momentum (1-3). The demand for improvements in presently available modelsor, these improvements beingin-adequate, for …
Continue reading at pubs.acs.org (other versions)

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/74Optical detectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/49Scattering, i.e. diffuse reflection within a body or fluid
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/05Flow-through cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90Plate chromatography, e.g. thin layer or paper chromatography
    • G01N30/94Development
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
    • G02B6/00Light guides
    • G02B6/24Coupling light guides
    • G02B6/26Optical coupling means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colour
    • G01J3/02Details
    • G01J3/0205Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01MTESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING STRUCTURES OR APPARATUS NOT OTHERWISE PROVIDED FOR
    • G01M11/00Testing of optical apparatus; Testing structures by optical methods not otherwise provided for
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00Photometry, e.g. photographic exposure meter

Similar Documents

Publication Publication Date Title
Bruno et al. On-column capillary flow cell utilizing optical waveguides for chromatographic applications
Bruin et al. Optimization and evaluation of the performance of arrangements for UV detection in high-resolution separations using fused-silica capillaries
Barth et al. Column liquid chromatography
EP0616211B1 (en) Optical detection arrangement for small volume chemical analysis of fluid samples
US5917606A (en) Photometric flow apparatus for small sample volumes and method of making same
US5444807A (en) Micro chemical analysis employing flow through detectors
US5235409A (en) Optical detection system for capillary separation columns
US5153679A (en) Apparatus and process for measuring light absorbance or fluorescence in liquid samples
JPH08500183A (en) Spectroscopic device for the analysis of small and trace substances
JP3432222B2 (en) Capillary flow cell for multiple wavelength detection
JP3186375B2 (en) Capillary detector cell and method for optimizing its performance
JPS5985945A (en) Liquid chromatograph device and its analysis method
Nolan et al. Photothermal refraction as a microbore liquid chromatography detector in femtomole amino acid determination
US9557293B2 (en) High-throughput multi-laser wave mixing detection methods and apparatus
CN100354620C (en) Method and apparatus for measuring light transmissivity
JPH09264840A (en) Absorber
US11598757B2 (en) Methods and systems for efficient separation of polarized UV light
Kenmore et al. Refractive-index detection by interferometric backscatter in packed-capillary high-performance liquid chromatography
US10668407B2 (en) Supercritical fluid chromatography laser wave mixing detection methods and apparatus
Schmoll et al. Statistical Test of Optical Fibers for Use in PMAS, the Potsdam Multi‐Aperture Spectrophotometer
EP0529541B1 (en) Double beam detector system for liquid chromatography
CN104316629A (en) Liquid phase multi-channel detector device
Abbas et al. Optical properties of axial-illumination flow cells for simultaneous absorbance-fluorescence detection in micro liquid chromatography
Brown et al. Interfacing a fiber-optic probe to a diode array UV-visible spectrophotometer for drug dissolution tests
US7420665B2 (en) Optical detection device with reduced light throughput oscillations