Zhao et al., 2016 - Google Patents
Ensemble‐decision Aliquot Ranking (eDAR) for CTC Isolation and AnalysisZhao et al., 2016
- Document ID
- 5828553959602418764
- Author
- Zhao M
- Schiro P
- Chiu D
- Publication year
- Publication venue
- Circulating tumor cells: isolation and analysis
External Links
Snippet
Summary Ensemble‐Decision Aliquot Ranking (eDAR) is operationally similar to flow cytometry but with significant differences. Aliquots containing circulating tumor cells (CTCs) are automatically sorted and collected into a small region on the microfluidic chip, where a …
- 238000004458 analytical method 0 title abstract description 7
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated micro-fluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11808767B2 (en) | Methods, compositions and systems for microfluidic assays | |
| Sesen et al. | Image-based single cell sorting automation in droplet microfluidics | |
| KR102625823B1 (en) | Systems and Methods | |
| US20230338952A1 (en) | System and method for automated single cell processing and analyses | |
| JP6576374B2 (en) | Aliquot selection by population detection | |
| US9442106B2 (en) | Simple and affordable method for immunophenotyping using a microfluidic chip sample preparation with image cytometry | |
| Chung et al. | Recent advances in miniaturized microfluidic flow cytometry for clinical use | |
| KR100746431B1 (en) | Cell sorter chip | |
| US9506927B2 (en) | Method for detecting low concentrations of specific cell from high concentrations of cell populations, and method for collecting and analyzing detected cell | |
| JP5241678B2 (en) | Microfluidic particle analysis system | |
| JP2021521417A (en) | Methods and equipment for single biological nanoparticle analysis | |
| EP2832845A1 (en) | Imaging cell sorter | |
| US10429387B2 (en) | Simple and affordable method for immuophenotyping using a microfluidic chip sample preparation with image cytometry | |
| Zhao et al. | Ensemble‐decision Aliquot Ranking (eDAR) for CTC Isolation and Analysis | |
| US20240302264A1 (en) | Methods of analyzing shaped particles containing cells using fluorescence activated cell sorting | |
| Zhao | Sensitive and High-throughput Detection, Separation and Analysis of Circulating Tumor Cells | |
| Zhang | Hands-free cytometry of whole blood: controlled antibody release from hydrogels for on-chip cell staining | |
| Gossett | High-Speed Manipulation of Cells and Particles for Single-Cell Analysis and Mechanophenotyping | |
| McGuigan et al. | Microfluidic isolation and fluorescence microscopy in a fully automated digital diagnostic instrument (Simoa HD-1 analyzer) | |
| MXPA00011492A (en) | Microfabricated cell sorter |