[go: up one dir, main page]

Zadina et al., 1985 - Google Patents

Interactions between the antiopiate Tyr-MIF-1 and the mu opiate morphiceptin at their respective binding sites in brain

Zadina et al., 1985

Document ID
6690679754122699706
Author
Zadina J
Kastin A
Publication year
Publication venue
Peptides

External Links

Snippet

The interactions between Tyr-MIF-1, a brain peptide with antiopiate activity, and the beta- casomorphins, a family of peptides derived from milk protein with opiate activity, were investigated by in vitro binding assays. Specific binding of 125 I-Tyr-MIF-1 to rat brain …
Continue reading at www.sciencedirect.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/695—Corticotropin [ACTH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Similar Documents

Publication Publication Date Title
Zadina et al. Interactions between the antiopiate Tyr-MIF-1 and the mu opiate morphiceptin at their respective binding sites in brain
Chang et al. Potent morphiceptin analogs: structure activity relationships and morphine-like activities.
Amiche et al. Dermenkephalin (Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2): a potent and fully specific agonist for the delta opioid receptor.
Schiller et al. Synthesis and in vitro opioid activity profiles of DALDA analogues
US5703045A (en) Treating disorders by application of insulin-like growth factors and analogs
Narita et al. Evidence for the existence of the β-endorphin-sensitive “ε-opioid receptor” in the brain: The mechanisms of ε-mediated antinociception
WO1997036607A1 (en) Synthetic peptide derivatives with nerve growth factor-like neurotrophic activity
McKnight et al. Pharmacological specificity of novel, synthetic, cyclic peptides as antagonists at tachykinin receptors
Payza et al. Neuropeptide FF receptors: structure-activity relationship and effect of morphine.
Suda et al. A novel opioid peptide, leumorphin, acts as an agonist at the κ opiate receptor
Varani et al. Pharmacology of [Tyr1] nociceptin analogs: receptor binding and bioassay studies
Roth et al. Nonopiate active proenkephalin‐derived peptides are secreted by T helper cells
Sanchez-Blazquez et al. Multiple opioid ligands and receptors in the control of nociception
Fichna et al. Opioid receptor binding and in vivo antinociceptive activity of position 3-substituted morphiceptin analogs
Balboni et al. Opioid pseudopeptides containing heteroaromatic or heteroaliphatic nuclei
Fichna et al. Characterization of antinociceptive activity of novel endomorphin-2 and morphiceptin analogs modified in the third position
Bozü et al. Synthesis and opioid binding activity of dermorphin analogues containing cyclic β-amino acids
EP0486520B1 (en) Dynorphin analogs specific for kappa opioid receptors
Coy et al. Tyrosine-modified analogs of methionine-enkephalin and their effects on the mouse vas deferens
US4388236A (en) Enkephalin-like compounds in bovine adrenal medulla
Duplaa et al. Influence of the replacement of amino acid by its D-enantiomer in the sequence of substance P. 1. Binding and pharmacological data
Evans et al. Candidate opioid peptides for interaction with the immune system
Takagi et al. Morphine-like analgesic actions of enkephalin-like peptides containing the Tyr-Arg unit
Pendleton et al. Studies defining minimal receptor domains for angiotensin II.
Schmidt et al. Structural modifications of the N-terminal tetrapeptide segment of [D-Ala2] deltorphin I: effects on opioid receptor affinities and activities in vitro and on antinociceptive potency