[go: up one dir, main page]

Parries et al., 1995 - Google Patents

The human urinary epidermal growth factor (EGF) precursor: isolation of a biologically active 160-kilodalton heparin-binding pro-EGF with a truncated carboxyl …

Parries et al., 1995

View HTML
Document ID
8206414013718484510
Author
Parries G
Chen K
Misono K
Cohen S
Publication year
Publication venue
Journal of Biological Chemistry

External Links

Snippet

In this report, we describe the isolation from human urine of a predominant 160-kDa epidermal growth factor (EGF)-immunoreactive glycoprotein that exhibits affinity for heparin. The purification procedure involved concentration and dialysis of 20-30-liter batches of fresh …
Continue reading at www.sciencedirect.com (HTML) (other versions)

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/48Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions

Similar Documents

Publication Publication Date Title
Hallahan et al. Dual site model for the organogenic activity of angiogenin.
US5453492A (en) 60 kDa transforming growth factor-β-binding protein and its use to detect or purify TGF-β
Kobayashi et al. The Pmel 17/silver locus protein. Characterization and investigation of its melanogenic function.
US6022540A (en) Ligands that modulate differentiation of mesenchymal stem cells
Parries et al. The human urinary epidermal growth factor (EGF) precursor: isolation of a biologically active 160-kilodalton heparin-binding pro-EGF with a truncated carboxyl terminus
Hu et al. An angiogenin-binding protein from endothelial cells.
Linder et al. Glycosylation differences contribute to distinct catalytic properties among bone alkaline phosphatase isoforms
Dong et al. Trafficking and proteolytic release of epidermal growth factor receptor ligands are modulated by their membrane-anchoring domains
JPH08503198A (en) OP-3 induced morphogenesis
Garcia et al. An evolutionarily conserved enzyme degrades transforming growth factor-alpha as well as insulin.
US5874277A (en) Proteins, their production and use
Vallee et al. Organogenesis and angiogenin
Breyer et al. The epidermal growth factor precursor isolated from murine kidney membranes. Chemical characterization and biological properties.
Riordan Structure and function of angiogenin
EP0342219A1 (en) Protein homologue of human angiogenine
EP0973914B1 (en) Proteins having lecithin-cholesterol acyltransferase-like activity, their production and use
US5876713A (en) Glutamine: fructose-6-phosphate amidotransferase, its production and use
WO2000073427A2 (en) Acetylcholinesterase-derived peptides and uses thereof
EP0897426B1 (en) Matrix metalloprotease
DE69530261T2 (en) Protein tyrosine phosphatases stimulated by cell density
Szoka et al. Enalapril stimulates collagen biosynthesis through prolidase-dependent mechanism in cultured fibroblasts
Ishibe et al. Activation of osteoblast insulin-like growth factor-II/cation-independent mannose-6-phosphate receptors by specific phosphorylated sugars and antibodies induce insulin-like growth factor-II effects
WO2005093057A1 (en) Truncated dance, dance complex and method of using these
Helwig et al. Isolation and characterization of a microvascular fraction from rabbit kidney cortex
Vallee et al. Chemical and biochemical properties of human angiogenin