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Chellappan et al., 1991 - Google Patents

The E2F transcription factor is a cellular target for the RB protein

Chellappan et al., 1991

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Document ID
8681757207651477539
Author
Chellappan S
Hiebert S
Mudryj M
Horowitz J
Nevins J
Publication year
Publication venue
Cell

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Snippet

Although it is generally believed that the product of the retinoblastoma susceptibility gene (RB7) is an important regulator of cell proliferation, the biochemical mechanism for its action is unclear. We now show that the RB protein is found in a complex with the E2F transcription …
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
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