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Velychko et al., 2019 - Google Patents

Excluding Oct4 from Yamanaka cocktail unleashes the developmental potential of iPSCs

Velychko et al., 2019

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Document ID
10083822074389774006
Author
Velychko S
Adachi K
Kim K
Hou Y
MacCarthy C
Wu G
Schöler H
Publication year
Publication venue
Cell stem cell

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Oct4 is widely considered the most important among the four Yamanaka reprogramming factors. Here, we show that the combination of Sox2, Klf4, and cMyc (SKM) suffices for reprogramming mouse somatic cells to induced pluripotent stem cells (iPSCs) …
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