[go: up one dir, main page]

Funakoshi et al., 1988 - Google Patents

Bioactivity of synthetic human pancreastatin on exocrine pancreas

Funakoshi et al., 1988

Document ID
11152843700273084753
Author
Funakoshi A
Miyasaka K
Nakamura R
Kitani K
Funakoshi S
Tamamura H
Fujii N
Yajima H
Publication year
Publication venue
Biochemical and biophysical research communications

External Links

Snippet

A biological activities of synthetic human pancreastatin (1–52) and its C-terminal fragment (24–52) were evaluated for the first time in the conscious rats. Both pancreastatins inhibited CCK-stimulated pancreatic secretion in a range of 20–200 pmol/kg/h with the same potency …
Continue reading at www.sciencedirect.com (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells

Similar Documents

Publication Publication Date Title
Funakoshi et al. Bioactivity of synthetic human pancreastatin on exocrine pancreas
Whitcomb et al. Characterization of saturable binding sites for circulating pancreatic polypeptide in rat brain
Adrian et al. Effect of peptide YY on gastric, pancreatic, and biliary function in humans
Blackburn et al. A radioimmunoassay for neurotensin in human plasma
Pappas et al. Peptide YY: metabolism and effect on pancreatic secretion in dogs
Bauer et al. Inhibitory effect of galanin on postprandial gastrointestinal motility and gut hormone release in humans
Hermansen Effects of substance P and other peptides on the release of somatostatin, insulin, and glucagon in vitro
Desrayaud et al. Effect of the P-glycoprotein inhibitor, SDZ PSC 833, on the blood and brain pharmacokinetics of colchicine
US20100209502A1 (en) Treatments Which Alleviate Functional Glycosylated Leptin Transport Factor for Controlling Weight and Obesity
Miles et al. Mechanisms of insulin resistance in experimental hyperinsulinemic dogs.
Hanabusa et al. Islet amyloid polypeptide (IAPP) secretion from islet cells and its plasma concentration in patients with non-insulin-dependent diabetes mellitus
Nakamura et al. Interactions between bile and pancreatic juice diversions on cholecystokinin release and pancreas in conscious rats
Dunning et al. Pancreatic and extrapancreatic galanin release during sympathetic neural activation
Marbach et al. From somatostatin to Sandostatin®: Pharmacodynamics and pharmacokinetics
Misumi et al. Effects of SMS 201-995, a somatostatin analogue, on the exocrine pancreatic secretion and gut hormone release in dogs
Ishizuka et al. Facilitatory effect of pituitary adenylate cyclase activating polypeptide on micturition in normal, conscious rats
Funakoshi et al. Effect of pancreastatin on pancreatic endocrine function in the conscious rat
Diez-Marques et al. Effects of somatostatin on cultured human mesangial cells
Watanabe et al. Release of cholecystokinin and exocrine pancreatic secretion in response to an elemental diet in human subjects
MATON et al. Infusion of cholecystokinin octapeptide in man: relation between plasma cholecystokinin concentrations and gallbladder emptying rates
Polonsky et al. Hepatic and renal metabolism of somatostatin-like immunoreactivity. Simultaneous assessment in the dog.
Funakoshi et al. Inhibitory effect of pancreastatin on pancreatic exocrine secretion in the conscious rat
Cantor et al. Inhibition of cholecystokinin-stimulated pancreaticobiliary output in man by the cholecystokinin receptor antagonist MK-329
Fisher et al. GI hormonal changes in diabetes influence pancreatic cancer growth
Beglinger et al. Effect of calcitonin and calcitonin gene-related peptide on pancreatic functions in man.