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Wisdom et al., 1992 - Google Patents

Transformation by FosB requires a trans-activation domain missing in FosB2 that can be substituted by heterologous activation domains.

Wisdom et al., 1992

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Document ID
116749545428102086
Author
Wisdom R
Yen J
Rashid D
Verma I
Publication year
Publication venue
Genes & development

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Snippet

Two functionally distinct proteins derived from the FosB gene by alternative splicing have recently been described. FosB protein transforms fibroblasts efficiently, whereas FosB2 protein, a carboxy-terminally truncated form of FosB, does not, despite the fact that both …
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