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Heikkinen et al., 2003 - Google Patents

1H MRS of a boron neutron capture therapy 10B-carrier, Lp-boronophenylalanine–fructose complex, BPA–F: phantom studies at 1.5 and 3.0 T

Heikkinen et al., 2003

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Document ID
11620622022673422766
Author
Heikkinen S
Kangasmäki A
Timonen M
Kankaanranta L
Häkkinen A
Lundbom N
Vähätalo J
Savolainen S
Publication year
Publication venue
Physics in Medicine & Biology

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Snippet

The quantification of a BNCT 10 B-carrier, Lp-boronophenylalanine–fructose complex (BPA– F), was evaluated using 1 H magnetic resonance spectroscopy (1 H MRS) with phantoms at 1.5 and 3.0 T. For proper quantification, relaxation times T 1 and T 2 are needed. While T 1 …
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    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences, Generation or control of pulse sequences ; Operator Console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • GPHYSICS
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    • G01R33/00Arrangements or instruments for measuring magnetic variables
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    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
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    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56341Diffusion imaging
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    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/565Correction of image distortions, e.g. due to magnetic field inhomogeneities
    • G01R33/56518Correction of image distortions, e.g. due to magnetic field inhomogeneities due to eddy currents, e.g. caused by switching of the gradient magnetic field
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    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
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    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/561Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
    • G01R33/5615Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
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