[go: up one dir, main page]

Brandt et al., 1986 - Google Patents

Functional and molecular characterization of a monoclonal antibody against human interleukin 2

Brandt et al., 1986

Document ID
12338746126795503869
Author
Brandt E
Altman A
Grünefeld M
Ulmer A
Flad H
Publication year
Publication venue
Immunobiology

External Links

Snippet

Human recombinant interleukin 2 (r-IL 2) was used as an immunizing antigen to yield a murine monoclonal antibody (mAb) termed BO-7. Although the antibody binds to r-IL2 more avidly, it also reacted strongly with IL 2 from natural sources in an enzyme-linked …
Continue reading at www.sciencedirect.com (other versions)

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74Inducing cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay
    • G01N33/564Immunoassay; Biospecific binding assay for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Similar Documents

Publication Publication Date Title
US8673301B2 (en) YKL-40 monoclonal antibody
EP0683234B2 (en) Antibody against beta-amyloid or their derivative and use thereof
EP0522159B1 (en) Antibody to pituitary adenylate cyclase activating peptide-pacap, hybridoma and assay for pacap
US5230999A (en) Monoclonal antibody to endothelin-3 or precursor thereof and use thereof
Brandt et al. Functional and molecular characterization of a monoclonal antibody against human interleukin 2
KR0174528B1 (en) Cancer related haptoglobin (hpr)
JP4374316B2 (en) Antibody to β-amyloid or a derivative thereof and use thereof
EP0331100A1 (en) Anti-endothelin antibodies and their use
KR0145406B1 (en) Monoclonal Antibodies Recognizing Gamma-Atrial Sodium Diuretic Polypeptides
EP0345811B1 (en) Monoclonal abtibodies specific for human fibrinopeptide A
EP0265847B1 (en) Monoclonal antibody reacting with TRF (interleukin-5)
AU616195B2 (en) Lectines fixing beta-d-galactoside
US5516643A (en) Immunochemical assays for cancer-associated SCM-recognition factor
JP2735986B2 (en) Antibodies to the product of the tumor suppressor gene WT
WO2012075333A2 (en) Her2delta16 peptides
US5171663A (en) Monoclonal antibody against regulatory protein, sgp 120
JP3107248B2 (en) Antibodies and immunochemical assays
US7173112B2 (en) Antibody to GALP and uses thereof
JPH0595794A (en) Human m-csf antibody and determination of human m-csf
EP0428518A1 (en) Monoclonal antibodies specific for the harvey, kirsten and n ras proteins and their use as diagnostic reagents
JPH05244990A (en) Rat il-1 antibody and method for measuring rat il-1
Medeiros et al. Monoclonal antibodies against the Tn-specific isolectin B4 from Vicia villosa seeds: Characterization of the epitope of the blocking antibody VV34
AU5000893A (en) Immunochemical assays for cancer-associated scm recognition factor
JPH06128300A (en) Antibody to product of cancer suppressing gene prohibitin