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Peters-Wendisch et al., 2001 - Google Patents

Pyruvate carboxylase is a major bottleneck for glutamate and lysine production by Corynebacterium glutamicum

Peters-Wendisch et al., 2001

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Document ID
13361907971259683712
Author
Peters-Wendisch P
Schiel B
Wendisch V
Katsoulidis E
Mockel B
Sahm H
Eikmanns B
Publication year
Publication venue
Journal of molecular microbiology and biotechnology

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Corynebacterium glutamicum possesses both phosphoenolpyruvate carboxylase (PEPCx) and pyruvate carboxylase (PCx) as anaplerotic enzymes for growth on carbohydrates. To analyze the significance of PCx for the amino acid production by this organism, the wild-type …
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