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Pitot et al., 1997 - Google Patents

Phase II trial of irinotecan in patients with metastatic colorectal carcinoma.

Pitot et al., 1997

Document ID
13368114500966564962
Author
Pitot H
Wender D
O'Connell M
Schroeder G
Goldberg R
Rubin J
Mailliard J
Knost J
Ghosh C
Kirschling R
Levitt R
Windschitl H
Publication year
Publication venue
Journal of Clinical Oncology

External Links

Snippet

PURPOSE To evaluate the objective tumor response rate and toxicities of patients with metastatic colorectal carcinoma treated with irinotecan hydrochloride (CPT-11). PATIENTS AND METHODS A total of 121 patients with advanced colorectal carcinoma--90 with prior …
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
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