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Okuyama et al., 1995 - Google Patents

Bone marrow stromal cells induce myeloid and lymphoid development of the sorted hematopoietic stem cells in vitro

Okuyama et al., 1995

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Document ID
13973597342681923728
Author
Okuyama R
Koguma M
Yanai N
Obinata M
Publication year

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Regulation of development of hematopoietic stem cells was examined by culturing Lin-c-Kit+ Sca1+ stem cells sorted from bone marrow (BM) cells by fluorescence-activated cell sorting on a layer of TBR59, a BM stromal cell line established from simian virus 40 T-antigen gene …
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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    • C12N5/0636—T lymphocytes
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    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
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    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/50—Cell markers; Cell surface determinants

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