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Vladisavljević et al., 2014 - Google Patents

Production of liposomes using microengineered membrane and co-flow microfluidic device

Vladisavljević et al., 2014

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Document ID
14992638971561537848
Author
Vladisavljević G
Laouini A
Charcosset C
Fessi H
Bandulasena H
Holdich R
Publication year
Publication venue
Colloids and surfaces A: physicochemical and engineering aspects

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Snippet

Two modified ethanol injection methods have been used to produce Lipoid® E80 and POPC (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine) liposomes:(i) injection of the organic phase through a microengineered nickel membrane kept under controlled shear conditions …
Continue reading at www.academia.edu (PDF) (other versions)

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F5/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F5/04—Injector mixers, i.e. one or more components being added to a flowing main component
    • B01F5/0403—Mixing conduits or tubes, i.e. conduits or tubes through which the main component is flown
    • B01F5/0471—Mixing conduits or tubes, i.e. conduits or tubes through which the main component is flown the additional component being introduced at the circumference of the conduit
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F13/00—Other mixers; Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
    • B01F13/0059—Micromixers
    • B01F13/0061—Micromixers using specific means for arranging the streams to be mixed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F5/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F5/04—Injector mixers, i.e. one or more components being added to a flowing main component
    • B01F5/0403—Mixing conduits or tubes, i.e. conduits or tubes through which the main component is flown
    • B01F5/045—Mixing conduits or tubes, i.e. conduits or tubes through which the main component is flown the additional component being introduced in the centre of the conduit
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F3/00—Mixing, e.g. dispersing, emulsifying, according to the phases to be mixed
    • B01F3/08—Mixing, e.g. dispersing, emulsifying, according to the phases to be mixed liquids with liquids; Emulsifying
    • B01F3/0807—Emulsifying
    • B01F2003/0823—Emulsifying characterized by the internal structure of the emulsion
    • B01F2003/0838—Multiple emulsions, in particular double emulsion, e.g. water in oil in water; Three-phase emulsion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0418—Geometrical information
    • B01F2215/0431—Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F5/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F5/06—Mixers in which the components are pressed together through slits, orifices, or screens; Static mixers; Mixers of the fractal type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F7/00—Mixers with rotary stirring devices in fixed receptacles, i.e. movement of the receptacle not being meant to effect the mixing; Kneaders
    • B01F7/0075—Mixers with rotary stirring devices in fixed receptacles, i.e. movement of the receptacle not being meant to effect the mixing; Kneaders the mixer being composed of a stator-rotor system with movable slits between surfaces facing each other, e.g. having intermeshing teeth or cylinders or having orifices
    • B01F7/00758—Mixers with rotary stirring devices in fixed receptacles, i.e. movement of the receptacle not being meant to effect the mixing; Kneaders the mixer being composed of a stator-rotor system with movable slits between surfaces facing each other, e.g. having intermeshing teeth or cylinders or having orifices the stator rotor system being formed by substantial flat surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F13/00—Other mixers; Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
    • B01F13/10—Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
    • B01F13/1013—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles

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