[go: up one dir, main page]

Golstein et al., 1978 - Google Patents

Mouse T cell-mediated cytolysis specifically triggered by cytophilic xenogeneic serum determinants: A caveat for the interpretation of experiments done under “ …

Golstein et al., 1978

Document ID
15321117296740541589
Author
Golstein P
Luciani M
Wagner H
Röllinghoff M
Publication year
Publication venue
The Journal of Immunology

External Links

Snippet

We have demonstrated by using a combination of in vivo priming and in vitro incubation that the injection into mice of cultured cells can lead to the development of cytolytic T cells as a function of the serum used for growing the injected cells. Moreover, mere injection of …
Continue reading at academic.oup.com (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes

Similar Documents

Publication Publication Date Title
Golstein et al. Mouse T cell-mediated cytolysis specifically triggered by cytophilic xenogeneic serum determinants: A caveat for the interpretation of experiments done under “syngeneic” conditions
US20240156927A1 (en) Method for activating t cells for cancer treatment
Ke et al. Ovalbumin injected with complete Freund's adjuvant stimulates cytolytic responses
Glaser Regulation of specific cell-mediated cytotoxic response against SV40-induced tumor associated antigens by depletion of suppressor T cells with cyclophosphamide in mice.
Harimoto et al. Inactivation of tumor‐specific CD8+ CTLs by tumor‐infiltrating tolerogenic dendritic cells
Takei et al. In vitro induction of cytotoxicity against syngeneic mastocytoma and its suppression by spleen and thymus cells from tumor-bearing mice
Barth Jr et al. Unique murine tumor-associated antigens identified by tumor infiltrating lymphocytes.
RU2009122204A (en) MICROORGANISMS AND THEIR FRACTIONS INDUCING CELL-SPECIFIC CELLULAR IMMUNITY
Bellone et al. In vitro priming of cytotoxic T lymphocytes against poorly immunogenic epitopes by engineered antigen‐presenting cells
Nickell et al. Isolation from Trypanosoma cruzi-infected mice of CD8+, MHC-restricted cytotoxic T cells that lyse parasite-infected target cells
Schendel et al. Tumor-specific Lysis of Human Renal Cell Carcinomas by Tumor-infiltrating Lymphocytes: Modulation of Recognition through Retroviral Transduction of TumorCells with Interleukin 2 Complementary DNA and Exogenous α Interferon Treatment
Dennert Evidence for non-identity of T killer and T helper cells sensitised to allogeneic cell antigens
Itoh et al. Partial purification of murine tumor-associated peptide epitopes common to histologically distinct tumors, melanoma and sarcoma, that are presented by H-2Kb molecules and recognized by CD8+ tumor-infiltrating lymphocytes.
Lonai et al. Studies on the effect of a thymic humoral factor on differentiation of thymus‐derived lymphocytes
Glaser Indomethacin‐sensitive suppressor cells regulate the cell‐mediated cytotoxic response to SV 40‐induced tumor‐associated antigens in mice
Baldwin et al. Induction of tumor-immune responses and their interaction with the developing tumor
McCARTHY et al. Recognition of MHC class I allodeterminants regulates the generation of MHC class II-specific CTL.
Ransom et al. Expression of class II major histocompatibility complex molecules correlates with human colon tumor vaccine efficacy
Klein et al. A murine cytotoxic T lymphocyte clone from the intestinal mucosa that is antigen specific for proliferation and displays broadly reactive inducible cytotoxic activity.
Levy et al. Xenogeneic serum-induced murine cytotoxic cells: I. The generation of effector components specific for self and allogeneic target cells
Atta et al. Enhanced expression of MHC class I molecules on cultured human thyroid follicular cells infected with reovirus through induction of type 1 interferons
Ponner et al. Induction of apoptosis reduces immunogenicity of human T‐cell lines in mice
Fisher et al. Problems in the physiology of class I and class II MHC molecules, and of CD45
Ranney Biological inhibitors of lymphoid cell division
Correale et al. In vitro generation of cytotoxic T lymphocytes against HLA-A2. 1-restricted peptides derived from human thymidylate synthase