Abu El-Asrar et al., 2025 - Google Patents
ADAMTS13 improves endothelial function and reduces inflammation in diabetic retinopathyAbu El-Asrar et al., 2025
View HTML- Document ID
- 16021794009424092976
- Author
- Abu El-Asrar A
- Nawaz M
- Ahmad A
- Siddiquei M
- Allegaert E
- Adyns L
- Vanbrabant L
- Gikandi P
- De Hertogh G
- Struyf S
- Opdenakker G
- Publication year
- Publication venue
- Cells
External Links
Snippet
The protease, a disintegrin and metalloproteinase with thrombospondin type 1 motif member 13 (ADAMTS13), known to cleave only the von Willebrand factor (VWF), has powerful regulatory effects on microvascular platelet adhesion, thrombosis, inflammation, and …
- 206010012689 Diabetic retinopathy 0 title abstract description 52
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/569—Immunoassay; Biospecific binding assay for micro-organisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Altalhi et al. | PAI-1 in diabetes: pathophysiology and role as a therapeutic target | |
| Huang et al. | The pathogenesis of sepsis and potential therapeutic targets | |
| El Hadri et al. | Inflammation, oxidative stress, senescence in atherosclerosis: thioredoxine-1 as an emerging therapeutic target | |
| Kwiatkowska et al. | Podocytes—The most vulnerable renal cells in preeclampsia | |
| El-Asrar et al. | ADAMTS13 improves endothelial function and reduces inflammation in diabetic retinopathy | |
| Cirillo et al. | A scoping review of the role of metalloproteinases in the pathogenesis of autoimmune pemphigus and pemphigoid | |
| Perrucci et al. | Cyclophilin A/EMMPRIN axis is involved in pro-fibrotic processes associated with thoracic aortic aneurysm of Marfan syndrome patients | |
| Abu El-Asrar et al. | CD40 Ligand–CD40 Interaction is an intermediary between inflammation and angiogenesis in proliferative diabetic retinopathy | |
| Pahk et al. | SP-8356, a novel inhibitor of CD147-cyclophilin a interactions, reduces plaque progression and stabilizes vulnerable plaques in apoE-deficient mice | |
| Spampinato et al. | Microglia contributes to baf-312 effects on blood–brain barrier stability | |
| Arnholdt et al. | Depletion of γδ T cells leads to reduced angiogenesis and increased infiltration of inflammatory M1-like macrophages in ischemic muscle tissue | |
| Rogerson et al. | ADAMTS-9 in mouse cartilage has aggrecanase activity that is distinct from ADAMTS-4 and ADAMTS-5 | |
| Chang et al. | Glycerol improves intracerebral hemorrhagic brain injury and associated kidney dysfunction in rats | |
| Hwang et al. | Changes in the systemic expression of sirtuin-1 and oxidative stress after intravitreal anti-vascular endothelial growth factor in patients with retinal vein occlusion | |
| Chen et al. | Doxycycline ameliorates the severity of experimental proliferative vitreoretinopathy in mice | |
| Bezerra et al. | In vitro and in vivo effects of serpinA1 on the modulation of transthyretin proteolysis | |
| Chen et al. | Metformin directly binds to MMP-9 to improve plaque stability | |
| Papakonstantinou et al. | ADAMTS13 in the New Era of TTP | |
| Chou et al. | B-cell activating factor enhances hepatocyte-driven angiogenesis via B-cell CLL/lymphoma 10/nuclear factor-kappab signaling during liver regeneration | |
| Lim et al. | Paricalcitol improves hypoxia-induced and TGF-β1-induced injury in kidney pericytes | |
| Bhattarai et al. | Endothelial specific deletion of autotaxin improves stroke outcomes | |
| Bouillet et al. | Molecular mechanisms of endothelialitis in SARS-CoV-2 infection: Evidence for VE-cadherin cleavage by ACE2 | |
| McRobb et al. | Radiation-stimulated translocation of CD166 and CRYAB to the endothelial surface provides potential vascular targets on irradiated brain arteriovenous malformations | |
| Pacinella et al. | Molecular links and clinical effects of inflammation and metabolic background on ischemic stroke: an update review | |
| Irqsusi et al. | The role of matrix metalloproteinases in thoracic aortic disease: are they indicators for the pathogenesis of dissections? |