MAckIE et al., 1990 - Google Patents
Dose-related mechanisms of immunosuppression mediated by murine anti-CD3 monoclonal antibody in pancreatic islet cell transplantation and delayed-type …MAckIE et al., 1990
View PDF- Document ID
- 16173487182853968163
- Author
- MAckIE J
- Pankewycz O
- BAsTos M
- Kelley V
- Strom T
- Publication year
- Publication venue
- Transplantation
External Links
Snippet
MATERIALS AND METHODS Mice. Six to 16-week-old male DBA/2, B6AF, BALB/c, and A/J mice were obtained from the Jackson Laboratory (Bar Harbor, ME). Transplants. Allogeneic pancreatic islet transplants were performed according to described techniques (5). Briefly …
- 210000004153 Islets of Langerhans 0 title abstract description 15
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation; Therapies using these preparations
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Faustman et al. | Prolongation of murine islet allograft survival by pretreatment of islets with antibody directed to Ia determinants. | |
| Butturini et al. | Use of recombinant granulocyte-macrophage colony stimulating factor in the Brazil radiation accident | |
| EP1061949B1 (en) | Cytokines and mitogens to inhibit graft-versus-host disease | |
| AU707211B2 (en) | Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease | |
| HARDY et al. | Pancreatic islet transplantation: induction of graft acceptance by ultraviolet irradiation of donor tissue | |
| Dye et al. | Specificity of the T cells that mediate and suppress adoptive immunotherapy of established tumors | |
| JP4256431B2 (en) | Use of cytokines, cells and mitogens to inhibit graft-versus-host disease | |
| MAckIE et al. | Dose-related mechanisms of immunosuppression mediated by murine anti-CD3 monoclonal antibody in pancreatic islet cell transplantation and delayed-type hypersensitivity | |
| Breard et al. | The role of p23, 30-bearing human macrophages in antigen-induced T lymphocyte responses | |
| Cohn et al. | Hematopoietic reconstitution and prevention of graft-versus-host disease with UVB-irradiated haploidentical murine spleen and marrow cells | |
| JIN et al. | Induction of stable chimerism and transplantation tolerance to rat islet and heart allografts by ultraviolet-B modulation of bone marrow cells | |
| US20040005300A1 (en) | Methods for enhancing engraftment of purified hematopoietic stem cells in allogeneic recipients | |
| PEcoRA et al. | Characterization of the in vitro sensitivity of human lymphoid and hematopoietic progenitors to L-leucyl-L-leucine methyl ester | |
| US6213127B1 (en) | Methods for treating cancer using allogeneic lymphocytes without graft vs host disease activity | |
| Thomas et al. | Effect of rabbit anti-human thymocyte globulin on lymphocyte subpopulations and functions following allotransplantation in the rhesus monkey | |
| Mizoguchi et al. | Genetic and stimulatory cell type requirements for inducing class I major histocompatibility complex alloantigen‐specific in vivo cytotoxic T cell immunity | |
| Oluwole et al. | SELECTIVE LYMPHOID IRRADIATION: II. Comparison with Total-Body Irradiation on Cardiac Allograft Survival in Rats | |
| Degiovanni et al. | Generation of cytolytic T lymphocytes in vitro. O XI. Accessory cell requirement in secondary responses to particulate alloantigen | |
| Lloyd et al. | Pancreas-graft immunogenicity and pretreatment with anti-class II monoclonal antibodies | |
| US20010014320A1 (en) | Methods for treating cancer using allogeneic lymphocytes without graft vs host disease activity | |
| Uchiyama et al. | Approach to withdrawal from tacrolimus in a fully allogeneic murine skin graft model | |
| Benhamou et al. | FETAL PANCREAS TRANSPLANTATION IN MINIATURE SWINE: V. The Functional and Immunomodulatory Effects of Ultraviolet Light on Fetal Pig Islets | |
| Kwak et al. | Tumor resistance induced by syngeneic bone marrow transplantation and enhanced by interleukin 2: a model for the graft versus leukemia reaction | |
| Burdick et al. | Antigenic requirement for induced rejection of long-surviving murine heart transplants. | |
| Seledtsov et al. | Induction of mixed allogeneic chimerism for leukemia |