Geczy et al., 2019 - Google Patents
Microfluidic approaches for the production of monodisperse, superparamagnetic microspheres in the low micrometer size rangeGeczy et al., 2019
- Document ID
- 16576827047279119949
- Author
- Geczy R
- Agnoletti M
- Hansen M
- Kutter J
- Saatchi K
- Häfeli U
- Publication year
- Publication venue
- Journal of Magnetism and Magnetic Materials
External Links
Snippet
The preparation of small, monodispersed magnetic microparticles through microfluidic approaches has been consistently challenging due to the high energy input needed for droplet break-off at such small diameters. In this work, we show the microfluidic production of …
- 238000004519 manufacturing process 0 title abstract description 61
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
- B01F13/00—Other mixers; Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
- B01F13/0059—Micromixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Yang et al. | Microfluidic assisted synthesis of multi-functional polycaprolactone microcapsules: incorporation of CdTe quantum dots, Fe 3 O 4 superparamagnetic nanoparticles and tamoxifen anticancer drugs | |
| US20230241219A1 (en) | Polymersomes, colloidosomes, liposomes, and other species associated with fluidic droplets | |
| Pessi et al. | Microfluidics-assisted engineering of polymeric microcapsules with high encapsulation efficiency for protein drug delivery | |
| Zhao et al. | Generation of Janus alginate hydrogel particles with magnetic anisotropy for cell encapsulation | |
| De La Vega et al. | Uniform polymer microspheres: monodispersity criteria, methods of formation and applications | |
| Fontana et al. | Microfluidics as a cutting-edge technique for drug delivery applications | |
| Geczy et al. | Microfluidic approaches for the production of monodisperse, superparamagnetic microspheres in the low micrometer size range | |
| US9550160B2 (en) | Methods for producing nanoparticles and using same | |
| Kong et al. | Droplet based microfluidic fabrication of designer microparticles for encapsulation applications | |
| Sundararajan et al. | Engineering polymeric Janus particles for drug delivery using microfluidic solvent dissolution approach | |
| US20110223314A1 (en) | Efficient microencapsulation | |
| Dehghani et al. | Simultaneous two drugs release form Janus particles prepared via polymerization-induced phase separation approach | |
| Yan et al. | Magnetically controllable generation of ferrofluid droplets | |
| CN103764265A (en) | Multiple emulsions and techniques for formulating multiple emulsions | |
| Brown et al. | Polymersome production on a microfluidic platform using pH sensitive block copolymers | |
| Hsu et al. | Sustained release of hydrophobic drugs by the microfluidic assembly of multistage microgel/poly (lactic-co-glycolic acid) nanoparticle composites | |
| Bokharaei et al. | Production of monodispersed magnetic polymeric microspheres in a microfluidic chip and 3D simulation | |
| Akamatsu et al. | Membrane-integrated glass capillary device for preparing small-sized water-in-oil-in-water emulsion droplets | |
| Schneider et al. | Effects of chemical and physical parameters in the generation of microspheres by hydrodynamic flow focusing | |
| Abbasi et al. | Microfluidic generation of particle-stabilized water-in-water emulsions | |
| Rabiee et al. | Microfluidic devices and drug delivery systems | |
| US10500167B2 (en) | Droplet-embedded microfibers, and methods and devices for preparing and using same | |
| Saqib et al. | Synthesis of anisotropic magnetic polymeric janus particles by in situ separation of magnetic nanoparticles in a microfluidic device | |
| Park et al. | Monodisperse micro-oil droplets stabilized by polymerizable phospholipid coatings as potential drug carriers | |
| Cai et al. | Controllable Monodisperse Amphiphilic Janus Microparticles |