[go: up one dir, main page]

Blake, 2006 - Google Patents

Instrumentation for preparative mass spectrometry

Blake, 2006

Document ID
16786006808721080455
Author
Blake T
Publication year

External Links

Snippet

Two preparative mass spectrometers have been designed and constructed as part of efforts at developing the ion soft-landing experiment into a standard proteomics tool for purifying biomolecules which retain their original bioactivity. The first preparative instrument was …
Continue reading at search.proquest.com (other versions)

Classifications

    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometer or separator tubes
    • H01J49/02Details
    • H01J49/10Ion sources; Ion guns
    • H01J49/16Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometer or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0404Capillaries used for transferring samples or ions
    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometer or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409Sample holders or containers
    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometer or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205Device types
    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometer or separator tubes
    • H01J49/02Details
    • H01J49/06Electron- or ion-optical arrangements
    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J37/00Discharge tubes with provision for introducing objects or material to be exposed to the discharge, e.g. for the purpose of examination or processing thereof
    • H01J37/02Details
    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J9/00Apparatus or processes specially adapted to the manufacture, installation, removal, maintenance of electric discharge tubes, discharge lamps, or parts thereof; Recovery of material from discharge tubes or lamps
    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J2237/00Discharge tubes exposing object to beam, e.g. for analysis treatment, etching, imaging

Similar Documents

Publication Publication Date Title
US11017990B2 (en) Compact mass spectrometer
US10978288B2 (en) Compact mass spectrometer
US7381373B2 (en) System and method for preparative mass spectrometry
Siuzdak Mass spectrometry for biotechnology
Blake et al. Preparative linear ion trap mass spectrometer for separation and collection of purified proteins and peptides in arrays using ion soft landing
Kandiah et al. Advances in ultrasensitive mass spectrometry of organic molecules
US6707036B2 (en) Ionization apparatus and method for mass spectrometer system
US6750448B2 (en) Preparative separation of mixtures by mass spectrometry
EP1764823A2 (en) System and method for landing of lons on a gas/liquid interface
US10354847B2 (en) Compact mass spectrometer
US10090138B2 (en) Compact mass spectrometer
WO2007112234A2 (en) Means and method for analyzing samples by mass spectrometry
GB2520787A (en) Compact mass spectrometer
Blake Instrumentation for preparative mass spectrometry
GB2520785A (en) Compact mass spectrometer
Wiseman Development of desorption electrospray ionization (DESI) mass spectrometry and its application to direct biological tissue analysis and molecular imaging
Navare Development of high-sensitivity atmospheric pressure (AP) matrix-assisted laser desorption/ionization (MALDI) and open air ionization techniques for the analysis of biomolecules by mass spectrometry
Gologan Mass spectrometry: Metamorphosis from an analytical technique to a preparative technology
Harper Development and application of an on-line liquid chromatography interface for the analysis of biomolecules by fourier transform ion cyclotron resonance mass spectrometry
Smith Design improvements for low flow electrospray mass spectrometry of biomolecules
Beck Collision velocity dependence of products formed via surface induced dissociation
Smith Developments of multiplexed and miniature two-dimensional quadrupole ion trap mass spectrometers
Zhao Development of nanoelectrospray and application to protein research and drug discovery
Keller Nanoliter chemistry combined with microspot MALDI TOF MS for sensitive protein and peptide characterization