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Sofeo et al., 2019 - Google Patents

Altering the substrate specificity of acetyl-CoA synthetase by rational mutagenesis of the carboxylate binding pocket

Sofeo et al., 2019

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Document ID
18256042325628678710
Author
Sofeo N
Hart J
Butler B
Oliver D
Yandeau-Nelson M
Nikolau B
Publication year
Publication venue
ACS Synthetic Biology

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Snippet

Acetyl-CoA synthetase (ACS) is a member of a large superfamily of enzymes that display diverse substrate specificities, with a common mechanism of catalyzing the formation of a thioester bond between Coenzyme A and a carboxylic acid, while hydrolyzing ATP to AMP …
Continue reading at pubs.acs.org (PDF) (other versions)

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