Tam et al., 1995 - Google Patents
Synthesis and applications of branched peptides in immunological methods and vaccinesTam et al., 1995
- Document ID
- 2235564784761328878
- Author
- Tam J
- et al.
- Publication year
- Publication venue
- Peptides: synthesis, structures & applications. Academic Press, Inc., New York, NY
External Links
Snippet
Synthesis and applications of branched peptides in immunological methods and vaccines Page
470 Synthesis and Applications of Branched Peptides in Immunological Methods and Vaccines
James P. Tam Vanderbilt University Medical Center Department of Microbiology and …
- 108090000765 processed proteins & peptides 0 title abstract description 219
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
- A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
- A61K47/48238—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the modifying agent being a protein, peptide, polyamino acid
- A61K47/48246—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the modifying agent being a protein, peptide, polyamino acid drug-peptide, protein or polyamino acid conjugates, i.e. the modifying agent being a protein, peptide, polyamino acid which being linked/complexed to a molecule that being the pharmacologically or therapeutically active agent
- A61K47/4833—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the modifying agent being a protein, peptide, polyamino acid drug-peptide, protein or polyamino acid conjugates, i.e. the modifying agent being a protein, peptide, polyamino acid which being linked/complexed to a molecule that being the pharmacologically or therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse Transcribing RNA Viruses
- C12N2740/00011—Reverse Transcribing RNA Viruses
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Tam | Recent advances in multiple antigen peptides | |
| Wiesmüller et al. | Novel low-molecular-weight synthetic vaccine against foot-and-mouth disease containing a potent B-cell and macrophage activator | |
| US5882645A (en) | Peptide compounds | |
| WJESMÜLLER et al. | Solid phase peptide synthesis of lipopeptide vaccines eliciting epitope‐specific B‐, T‐helper and T‐killer cell response | |
| Vepřek et al. | Peptide and glycopeptide dendrimers. Part I | |
| Defoort et al. | Macromolecular assemblage in the design of a synthetic AIDS vaccine. | |
| AU2003249778B2 (en) | Novel immunogenic lipopeptides comprising T-helper and cytotoxic T lymphocyte (CTL) epitopes | |
| US5580563A (en) | Multiple antigen peptide system having adjuvant properties, vaccines prepared therefrom and methods of use thereof | |
| AU2007327829B2 (en) | Coiled-coil lipopeptide helical bundles and synthetic virus-like particles | |
| Muller et al. | Antigenic properties and protective capacity of a cyclic peptide corresponding to site A of influenza virus haemagglutinin | |
| Zeng et al. | Totally synthetic lipid-containing polyoxime peptide constructs are potent immunogens | |
| Deprez et al. | Comparative efficiency of simple lipopeptide constructs for in vivo induction of virus-specific CTL | |
| JP2006257095A (en) | Heterodimer polypeptide immunogen carrier composition and method | |
| Huang et al. | Lipophilic multiple antigen peptide system for peptide immunogen and synthetic vaccine | |
| US6074650A (en) | Membrane anchor/active compound conjugate, its preparation and its uses | |
| Tam | Synthesis and applications of branched peptides in immunological methods and vaccines | |
| US6024964A (en) | Membrane anchor/active compound conjugate, its preparation and its uses | |
| JP3821305B2 (en) | Cytotoxic T lymphocyte-derived lipopeptides and vaccines | |
| Bessler et al. | Bacterial cell wall components as immunomodulators—I. Lipopeptides as adjuvants for parenteral and oral immunization | |
| US20110262473A1 (en) | Synthetic vaccine component | |
| EP0961793A1 (en) | Polymers incorporating peptides | |
| GB2282813A (en) | Annular antigen scaffolds comprising thioether linkages | |
| US20090104220A1 (en) | Method to Make a Peptide-Carrier Conjugate with a High Immunogenicity | |
| Rajnavölgyi et al. | Structural characteristics influencing the carrier function of synthetic branched polypeptides based on poly [Lys-(DL-Ala) 3)] backbone | |
| Nardelli et al. | The MAP system: A flexible and unambiguous vaccine design of branched peptides |