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Bürkle et al., 1992 - Google Patents

Studies on Poly (ADP-Ribosyl) ation in DNA Amplification and Mammalian Longevity

Bürkle et al., 1992

Document ID
2557495734403161977
Author
Bürkle A
Grube K
Küpper J
Publication year
Publication venue
ADP-ribosylation Reactions

External Links

Snippet

Poly (ADP-ribosyl) ation is a posttranslational protein modification catalyzed by poly (ADP- ribose) polymerase (PARP1), a highly conserved nuclear enzyme which uses nicotinamide- adenine dinucleotide (NAD) as substrate (for review, see Althaus &). Poly (ADP-ribosyl) …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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