Pirrung et al., 2006 - Google Patents
Photoremovable protecting groups in DNA synthesis and microarray fabricationPirrung et al., 2006
- Document ID
- 2643300417066330807
- Author
- Pirrung M
- Rana V
- Publication year
- Publication venue
- Dynamic Studies in Biology: Phototrig-gers Photoswitches and Caged Biomolecules, John Wiley & Sons, Inc
External Links
Snippet
Light and DNA are sometimes thought to be incompatible, with great concerns about the genetic mutations created by excessive sunlight exposure. However, when applied judiciously, light is an excellent reagent for promoting chemical changes in DNA molecules …
- 229920003013 deoxyribonucleic acid 0 title abstract description 69
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/11—Compounds covalently bound to a solid support
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—For creating libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6426184B1 (en) | Method and apparatus for chemical and biochemical reactions using photo-generated reagents | |
| Agbavwe et al. | Efficiency, error and yield in light-directed maskless synthesis of DNA microarrays | |
| Pirrung | How to make a DNA chip | |
| US6887665B2 (en) | Methods of array synthesis | |
| US6147205A (en) | Photocleavable protecting groups and methods for their use | |
| JP5274852B2 (en) | Oligomer probe array substrate wherein photodegradable compound is coupled with said compound, oligomer probe array, and method for producing the same | |
| ES2547917T3 (en) | Photolabile protecting groups containing a diarylsulfide skeleton | |
| JP2000511560A (en) | Chemical amplification for the synthesis of patterned arrays | |
| JP2005523232A (en) | Photocleavable protecting group | |
| Pirrung et al. | Photoremovable protecting groups in DNA synthesis and microarray fabrication | |
| Pirrung et al. | Photoremovable protecting groups in DNA synthesis and microarray fabrication | |
| US20080206851A1 (en) | Methods and compositions for RNA synthesis | |
| JP4593928B2 (en) | Method for cleaving unstable functional groups from compounds | |
| US20080206850A1 (en) | Methods and compositions for DNA synthesis | |
| EP1589024B1 (en) | Photolabile protecting groups | |
| US7301049B2 (en) | Photolabile esters and their uses | |
| US20040248162A1 (en) | Releasable polymer arrays | |
| US7144700B1 (en) | Photolithographic solid-phase polymer synthesis | |
| EP1258288A2 (en) | Method and apparatus for chemical and biochemical reactions using photo-generated reagents | |
| US20230092024A1 (en) | Increasing Efficiency Of Photochemical Reactions On Substrates | |
| Ibáñez-Redín et al. | D4. 1 Chemistry for DNA on wafers | |
| US20050181421A1 (en) | Methods of array synthesis | |
| Song et al. | Selectivity of hybridization controlled by the density of solid phase synthesized DNA probes on glass substrates | |
| McGall et al. | High-density oligonucleotide probe arrays | |
| Fallon | Studies towards the development of novel chemical methodologies for light-directed DNA synthesis |