MX346763B - Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. - Google Patents
Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné.Info
- Publication number
- MX346763B MX346763B MX2012003694A MX2012003694A MX346763B MX 346763 B MX346763 B MX 346763B MX 2012003694 A MX2012003694 A MX 2012003694A MX 2012003694 A MX2012003694 A MX 2012003694A MX 346763 B MX346763 B MX 346763B
- Authority
- MX
- Mexico
- Prior art keywords
- acne
- ddo
- semi
- topical composition
- eliminating
- Prior art date
Links
- 208000002874 Acne Vulgaris Diseases 0.000 title abstract 5
- 206010000496 acne Diseases 0.000 title abstract 5
- PFRGXCVKLLPLIP-UHFFFAOYSA-N diallyl disulfide Chemical class C=CCSSCC=C PFRGXCVKLLPLIP-UHFFFAOYSA-N 0.000 title abstract 2
- ISWRGOKTTBVCFA-UHFFFAOYSA-N pirfenidone Chemical compound C1=C(C)C=CC(=O)N1C1=CC=CC=C1 ISWRGOKTTBVCFA-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003073 pirfenidone Drugs 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 239000004599 antimicrobial Substances 0.000 abstract 2
- 230000003510 anti-fibrotic effect Effects 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 230000002421 anti-septic effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención describe una composición tópica semisólida conteniendo Pirfenidona y un antimicrobiano/antiséptico como Dialil Óxido de Disulfuro Modificado (ODD-M) y su proceso de fabricación, que ofrece ventajas sobre otras formas farmacéuticas de administración cutánea conocidas en el estado de la técnica, que es útil como agente anti-fibrótico, anti-inflamatorio y antiséptico en la prevención, tratamiento y reversión del acné y las lesiones post-acnéicas. Dicha composición también es útil para disminuir el tono rojizo de la piel, para detener la formación de nuevos brotes de acné, para revertir los brotes ya existentes y para regenerar la piel dañada a consecuencia del acné.
Priority Applications (27)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2012003694A MX346763B (es) | 2012-03-28 | 2012-03-28 | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. |
| PCT/MX2013/000027 WO2013147577A1 (es) | 2012-03-28 | 2013-02-27 | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné |
| AU2013240709A AU2013240709A1 (en) | 2012-03-28 | 2013-02-27 | Semi-solid topical composition which contains pirfenidone and modified diallyl disulphide oxide (m-ddo) for eliminating or preventing acne |
| IN8067DEN2014 IN2014DN08067A (es) | 2012-03-28 | 2013-02-27 | |
| MA37377A MA20150062A1 (fr) | 2012-03-28 | 2013-02-27 | Composition topique semi-solide contenant de la pirfénidone et de l'oxyde de disulfure dialyle modifié (odd-m) pour éliminer ou prévenir l'acné |
| JP2015503144A JP2015513359A (ja) | 2012-03-28 | 2013-02-27 | 座瘡の排除又は予防用のピルフェニドンと改変ジアリルジスルフィド酸化物(m−ddo)とを含む半固形局所組成物 |
| EP13716457.0A EP2832354A1 (en) | 2012-03-28 | 2013-02-27 | Semi-solid topical composition which contains pirfenidone and modified diallyl disulphide oxide (m-ddo) for eliminating or preventing acne |
| US14/388,447 US20150148382A1 (en) | 2012-03-28 | 2013-02-27 | Semi-solid topical composition which contains pirfenidone and modified diallyl disulphide oxide (m-ddo) for eliminating or preventing acne |
| EA201401031A EA201401031A1 (ru) | 2012-03-28 | 2013-02-27 | Полутвёрдая композиция для местного применения, которая содержит пирфенидон и модифицированный диаллилдисульфид оксид (m-ddo) для удаления или предупреждения угрей |
| SG11201406035VA SG11201406035VA (en) | 2012-03-28 | 2013-02-27 | Semi-solid topical composition which contains pirfenidone and modified diallyl disulphide oxide (m-ddo) for eliminating or preventing acne |
| CN201380023489.8A CN104334171A (zh) | 2012-03-28 | 2013-02-27 | 用于消除或预防痤疮的包含吡非尼酮和改性二烯丙基二硫化物氧化物(m-ddo)的半固体局部组合物 |
| KR1020147030122A KR20140146144A (ko) | 2012-03-28 | 2013-02-27 | 여드름을 제거 또는 예방하기 위한 피르페니돈과 변성 다이알릴 다이설파이드 옥사이드(m-ddo)를 함유하는 반고체 국소 조성물 |
| CA2868729A CA2868729C (en) | 2012-03-28 | 2013-02-27 | Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (m-ddo) for eliminating or preventing acne |
| UY0001034700A UY34700A (es) | 2012-03-28 | 2013-03-20 | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné |
| ARP130100926A AR090457A1 (es) | 2012-03-28 | 2013-03-21 | Composicion topica semisolida conteniendo pirfenidona y dialil oxido de disulfuro modificado (odd-m) para eliminar o prevenir el acne |
| TNP2014000396A TN2014000396A1 (en) | 2012-03-28 | 2014-09-22 | Semi-solid topical composition which contains pirfenidone and modified diallyl disulphide oxide (m-ddo) for eliminating or preventing acne |
| IL234816A IL234816A0 (en) | 2012-03-28 | 2014-09-23 | A semi-solid topical preparation containing pirfenidone and modified diallyl disulfide oxide for the treatment or prevention of acne |
| CO14211037A CO7071140A2 (es) | 2012-03-28 | 2014-09-24 | Composición topica semisolida conteniendo pirfenidona y dialil oxido de disulfuro modificado (odd-m) para eliminar o prevenir el acne |
| DO2014000218A DOP2014000218A (es) | 2012-03-28 | 2014-09-26 | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné |
| CU2014000114A CU20140114A7 (es) | 2012-03-28 | 2014-09-26 | Compisición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné |
| PH12014502154A PH12014502154A1 (en) | 2012-03-28 | 2014-09-26 | Semi-solid topical composition which contains pirfenidone and modified diallyl disulphide oxide (m-ddo) for eliminating or preventing acne |
| CL2014002591A CL2014002591A1 (es) | 2012-03-28 | 2014-09-26 | Composicion topica semisolida que comprende pirfenidona, dialil oxido de disulfuro modificado (odd-m), un agente gelificante y otros excipientes o aditivos; proceso para fabricarla; metodo de tratamiento; y su uso para eliminar, reducir o prevenir el acne. |
| US15/098,970 US9949959B2 (en) | 2012-03-28 | 2016-04-14 | Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (M-DDO) for eliminating or preventing acne |
| US15/920,822 US20180214434A1 (en) | 2012-03-28 | 2018-03-14 | Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (m-ddo) for eliminating or preventing acne |
| US16/534,980 US11013727B2 (en) | 2012-03-28 | 2019-08-07 | Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (M-DDO) for eliminating or preventing acne |
| US17/328,685 US11766426B2 (en) | 2012-03-28 | 2021-05-24 | Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (M-DDO) for eliminating or preventing acne |
| US18/449,747 US20240216350A1 (en) | 2012-03-28 | 2023-08-15 | Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (m-ddo) for eliminating or preventing acne |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2012003694A MX346763B (es) | 2012-03-28 | 2012-03-28 | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2012003694A MX2012003694A (es) | 2013-09-30 |
| MX346763B true MX346763B (es) | 2017-03-31 |
Family
ID=48096131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012003694A MX346763B (es) | 2012-03-28 | 2012-03-28 | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. |
Country Status (22)
| Country | Link |
|---|---|
| US (6) | US20150148382A1 (es) |
| EP (1) | EP2832354A1 (es) |
| JP (1) | JP2015513359A (es) |
| KR (1) | KR20140146144A (es) |
| CN (1) | CN104334171A (es) |
| AR (1) | AR090457A1 (es) |
| AU (1) | AU2013240709A1 (es) |
| CA (1) | CA2868729C (es) |
| CL (1) | CL2014002591A1 (es) |
| CO (1) | CO7071140A2 (es) |
| CU (1) | CU20140114A7 (es) |
| DO (1) | DOP2014000218A (es) |
| EA (1) | EA201401031A1 (es) |
| IL (1) | IL234816A0 (es) |
| IN (1) | IN2014DN08067A (es) |
| MA (1) | MA20150062A1 (es) |
| MX (1) | MX346763B (es) |
| PH (1) | PH12014502154A1 (es) |
| SG (1) | SG11201406035VA (es) |
| TN (1) | TN2014000396A1 (es) |
| UY (1) | UY34700A (es) |
| WO (1) | WO2013147577A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2007009796A (es) | 2007-08-14 | 2009-02-25 | Cell Therapy And Technology S | Gel conteniendo pirfenidona. |
| MX2011007675A (es) | 2011-07-19 | 2012-07-11 | Cell Therapy And Technology S A De C V | Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas. |
| MX346763B (es) | 2012-03-28 | 2017-03-31 | Cell Therapy And Tech S A De C V | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. |
| MX356551B (es) | 2012-08-23 | 2018-06-04 | Grupo Medifarma S A De C V Star | Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné. |
| US10233195B2 (en) | 2014-04-02 | 2019-03-19 | Intermune, Inc. | Anti-fibrotic pyridinones |
| CN106491517B (zh) * | 2016-11-23 | 2019-12-06 | 佛山科学技术学院 | 吡非尼酮pva水凝胶的制备方法及吡非尼酮pva水凝胶 |
| US20180360751A1 (en) * | 2017-06-19 | 2018-12-20 | Advanced Fibrosis Research LLC | Transdermal cream for treating Dupuytren's Contracture |
| MX366086B (es) * | 2017-08-15 | 2019-06-27 | Cell Therapy And Tech S A De C V | Composicion topica semisolida conteniendo un agente antimicrobiano y pirfenidona para el tratamiento de daños cronicos de la piel. |
| MX368750B (es) * | 2018-08-31 | 2019-10-15 | Cell Therapy And Tech S A De C V | Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular. |
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2012
- 2012-03-28 MX MX2012003694A patent/MX346763B/es active IP Right Grant
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2013
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- 2013-02-27 MA MA37377A patent/MA20150062A1/fr unknown
- 2013-02-27 KR KR1020147030122A patent/KR20140146144A/ko not_active Withdrawn
- 2013-02-27 AU AU2013240709A patent/AU2013240709A1/en not_active Abandoned
- 2013-02-27 SG SG11201406035VA patent/SG11201406035VA/en unknown
- 2013-02-27 IN IN8067DEN2014 patent/IN2014DN08067A/en unknown
- 2013-02-27 JP JP2015503144A patent/JP2015513359A/ja active Pending
- 2013-02-27 EP EP13716457.0A patent/EP2832354A1/en not_active Withdrawn
- 2013-02-27 US US14/388,447 patent/US20150148382A1/en not_active Abandoned
- 2013-02-27 CA CA2868729A patent/CA2868729C/en active Active
- 2013-02-27 EA EA201401031A patent/EA201401031A1/ru unknown
- 2013-02-27 WO PCT/MX2013/000027 patent/WO2013147577A1/es active Application Filing
- 2013-03-20 UY UY0001034700A patent/UY34700A/es unknown
- 2013-03-21 AR ARP130100926A patent/AR090457A1/es unknown
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2014
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- 2014-09-23 IL IL234816A patent/IL234816A0/en unknown
- 2014-09-24 CO CO14211037A patent/CO7071140A2/es unknown
- 2014-09-26 CU CU2014000114A patent/CU20140114A7/es unknown
- 2014-09-26 DO DO2014000218A patent/DOP2014000218A/es unknown
- 2014-09-26 PH PH12014502154A patent/PH12014502154A1/en unknown
- 2014-09-26 CL CL2014002591A patent/CL2014002591A1/es unknown
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2016
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2018
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Also Published As
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|---|---|
| CL2014002591A1 (es) | 2015-01-16 |
| IL234816A0 (en) | 2014-12-31 |
| US20200061040A1 (en) | 2020-02-27 |
| US20180214434A1 (en) | 2018-08-02 |
| PH12014502154A1 (en) | 2014-12-10 |
| AU2013240709A1 (en) | 2014-11-06 |
| US20160228424A1 (en) | 2016-08-11 |
| EA201401031A1 (ru) | 2015-05-29 |
| US20240216350A1 (en) | 2024-07-04 |
| SG11201406035VA (en) | 2014-11-27 |
| US11766426B2 (en) | 2023-09-26 |
| US9949959B2 (en) | 2018-04-24 |
| US20210346360A1 (en) | 2021-11-11 |
| DOP2014000218A (es) | 2014-12-15 |
| CA2868729A1 (en) | 2013-10-03 |
| IN2014DN08067A (es) | 2015-05-01 |
| CU20140114A7 (es) | 2015-01-29 |
| US20150148382A1 (en) | 2015-05-28 |
| MA20150062A1 (fr) | 2015-02-27 |
| UY34700A (es) | 2013-10-31 |
| CN104334171A (zh) | 2015-02-04 |
| KR20140146144A (ko) | 2014-12-24 |
| TN2014000396A1 (en) | 2015-12-21 |
| JP2015513359A (ja) | 2015-05-11 |
| WO2013147577A1 (es) | 2013-10-03 |
| CA2868729C (en) | 2020-10-20 |
| MX2012003694A (es) | 2013-09-30 |
| AR090457A1 (es) | 2014-11-12 |
| CO7071140A2 (es) | 2014-09-30 |
| US11013727B2 (en) | 2021-05-25 |
| EP2832354A1 (en) | 2015-02-04 |
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