MX354260B - Una tira de almohadilla individual para un ensayo de flujo lateral mejorado y un dispositivo de análisis que usa la misma. - Google Patents
Una tira de almohadilla individual para un ensayo de flujo lateral mejorado y un dispositivo de análisis que usa la misma.Info
- Publication number
- MX354260B MX354260B MX2014000830A MX2014000830A MX354260B MX 354260 B MX354260 B MX 354260B MX 2014000830 A MX2014000830 A MX 2014000830A MX 2014000830 A MX2014000830 A MX 2014000830A MX 354260 B MX354260 B MX 354260B
- Authority
- MX
- Mexico
- Prior art keywords
- present
- lateral flow
- strip
- same
- flow assay
- Prior art date
Links
- 238000003556 assay Methods 0.000 title abstract 4
- 238000004587 chromatography analysis Methods 0.000 abstract 3
- 102000001554 Hemoglobins Human genes 0.000 abstract 2
- 108010054147 Hemoglobins Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000523 sample Substances 0.000 abstract 2
- 239000012491 analyte Substances 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 239000007790 solid phase Substances 0.000 abstract 1
- 230000000007 visual effect Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
- G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/521—Single-layer analytical elements
- G01N33/523—Single-layer analytical elements the element being adapted for a specific analyte
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01049—Glucose-6-phosphate dehydrogenase (1.1.1.49)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/98—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving alcohol, e.g. ethanol in breath
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/90209—Oxidoreductases (1.) acting on NADH or NADPH (1.6), e.g. those with a heme protein as acceptor (1.6.2) (general), Cytochrome-b5 reductase (1.6.2.2) or NADPH-cytochrome P450 reductase (1.6.2.4)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
La presente invención se refiere a una tira para un ensayo de flujo lateral mejorado de una muestra biológica en un ensayo de cromatografía de flujo lateral y en un solo plano usando un dispositivo de análisis que contiene la misma. La tira de la presente invención consiste en una almohadilla individual, que puede mejorar el ensayo de flujo lateral proporcionando un procedimiento fácil y sencillo y una lectura visual clara. La tira de la presente invención consiste en una zona de aplicación de la muestra (muestra) y una zona de reactivo-resultante donde se deposita la mezcla de reacción (reactivo) que están en el mismo plano. Además, la presente invención proporciona un procedimiento cromatográfico en el que se separa la hemoglobina del analito por una cromatografía diferencial sobre la fase sólida. Cualquier interferencia de detección del resultado por la hemoglobina queda eliminada por la presente invención. La presente invención proporciona ventajas que incluyen un procedimiento fácil y sencillo con una respuesta rápida y clara. Una tira par un ensayo de enzima de flujo cromatográfico lateral para un analito preseleccionado en una muestra de sangre, caracterizada porque consiste en: una almohadilla única; y un sustrato depositado en forma seca, donde el analito comprende la enzima, donde la almohadilla única está pretratada con un tampón de lisis que comprende un detergente iónico o no-iónico, y donde la hemoglobina d ela muestra de sangre migra en la tira más rápido que el analito.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161510762P | 2011-07-22 | 2011-07-22 | |
| PCT/US2012/047625 WO2013016200A1 (en) | 2011-07-22 | 2012-07-20 | A single-pad strip for an improved lateral flow assay and a test device using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014000830A MX2014000830A (es) | 2014-07-09 |
| MX354260B true MX354260B (es) | 2018-02-21 |
Family
ID=47556024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014000830A MX354260B (es) | 2011-07-22 | 2012-07-20 | Una tira de almohadilla individual para un ensayo de flujo lateral mejorado y un dispositivo de análisis que usa la misma. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9575056B2 (es) |
| EP (1) | EP2734647B1 (es) |
| JP (1) | JP6067701B2 (es) |
| KR (1) | KR101751205B1 (es) |
| CN (2) | CN108107211B (es) |
| BR (1) | BR112014001544B1 (es) |
| CA (1) | CA2841976C (es) |
| MX (1) | MX354260B (es) |
| PH (2) | PH12014500147A1 (es) |
| WO (1) | WO2013016200A1 (es) |
| ZA (1) | ZA201400481B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2855363C (en) * | 2011-11-10 | 2019-02-12 | The Administrators Of The Tulane Educational Fund | Paper based diagnostic test |
| US9949671B2 (en) | 2013-03-13 | 2018-04-24 | Orthoaccel Technologies, Inc. | Diagnostic mouthpieces |
| EP3362180B1 (en) | 2015-10-15 | 2020-06-17 | Inbios International Inc. | Multiplexed lateral flow assay systems and methods for their use |
| US10983119B2 (en) | 2016-01-25 | 2021-04-20 | General Electric Company | Device for rapid diagnostic tests to detect antigens with improved sensitivity |
| US11041860B2 (en) * | 2016-03-18 | 2021-06-22 | Analytical Diagnostic Solutions, Inc. | Point-of-care device for the colorimetric determination of hemoglobin and glucose-6-phosphate dehydrogenase in biological samples |
| KR20180004028A (ko) * | 2016-06-30 | 2018-01-10 | 휴마시스 주식회사 | 효소 활성도 측정 및 면역학적 측정을 이용한 질환 진단 동시분석용 키트 |
| KR20180004027A (ko) * | 2016-06-30 | 2018-01-10 | 휴마시스 주식회사 | 효소 활성도 분석용 키트 |
| KR101974645B1 (ko) * | 2016-12-02 | 2019-05-02 | 에스디 바이오센서 주식회사 | 전체-헤모글로빈 및 포도당-6-인산 탈수소효소 동시 측정용 스트립, 그 제조방법 및 그 응용 |
| US11585882B2 (en) * | 2018-04-11 | 2023-02-21 | Mars Sciences Limited | Superparamagnetic particle imaging and its applications in quantitative multiplex stationary phase diagnostic assays |
| US10422729B1 (en) | 2019-03-08 | 2019-09-24 | Biodesix, Inc. | Blood sample separation devices and methods |
| EP4077657A4 (en) | 2019-12-18 | 2023-12-06 | Rapid Pathogen Screening, Inc. | SELECTIVE LYSIS OF WHITE BLOOD CELLS FOR IMMUNOASSAY SYSTEMS |
| EP4121505A4 (en) * | 2020-03-17 | 2024-05-01 | Detect, Inc. | REAGENT CARRIERS FOR RAPID DIAGNOSTIC TESTS |
| WO2022056078A1 (en) | 2020-09-11 | 2022-03-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Rnase h-assisted detection assay for rna (radar) |
| CN117965679A (zh) * | 2024-03-29 | 2024-05-03 | 深圳市亿立方生物技术有限公司 | G6pd酶活检测试剂盒及其制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU640162B2 (en) * | 1989-08-28 | 1993-08-19 | Lifescan, Inc. | Blood separation and analyte detection techniques |
| GB9120633D0 (en) * | 1991-09-27 | 1991-11-06 | Univ Brunel | Detection of malignant and pre-malignant conditions |
| DE69220871T2 (de) * | 1991-10-03 | 1997-11-20 | Bayer Ag | Vorrichtung und Verfahren zur Auftrennung und Analyse von Vollblut |
| US5902731A (en) * | 1998-09-28 | 1999-05-11 | Lifescan, Inc. | Diagnostics based on tetrazolium compounds |
| US6036659A (en) | 1998-10-09 | 2000-03-14 | Flexsite Diagnostics, Inc. | Collection device for biological samples and methods of use |
| US6420128B1 (en) * | 2000-09-12 | 2002-07-16 | Lifescan, Inc. | Test strips for detecting the presence of a reduced cofactor in a sample and method for using the same |
| US20020182600A1 (en) * | 2001-04-11 | 2002-12-05 | Smith Jack V. | Method for assaying biological and other constituents using synthetic nucleounits in lateral flow, liquid, and dry chemistry techniques |
| US20030045003A1 (en) | 2001-07-20 | 2003-03-06 | Smith Jack V. | Method for detection of the adulterant urine luckTM in urine using liquid chemistry, dry chemistry test pads, and lateral flow |
| US20040219694A1 (en) | 2001-09-11 | 2004-11-04 | Chittock Roger Steward | Lateral flow test format for enzyme assays |
| JP2005520795A (ja) * | 2001-12-12 | 2005-07-14 | コンフォーマ・セラピューティクス・コーポレイション | Ｈｓｐ９０阻害活性を有するプリン類似体 |
| US20040241779A1 (en) | 2003-02-24 | 2004-12-02 | Piasio Roger N. | Dry chemistry, lateral flow-reconstituted chromatographic enzyme-driven assays |
| JP4566983B2 (ja) | 2003-02-24 | 2010-10-20 | バイナックス インコーポレイティッド | 乾式化学の側方流動−再構成されたクロマトグラフィー的酵素駆動式アッセイ法 |
| CN101031798B (zh) * | 2004-07-29 | 2012-06-27 | 瑞莱诊断体系有限公司 | 侧向流系统和测定 |
| US7504235B2 (en) | 2005-08-31 | 2009-03-17 | Kimberly-Clark Worldwide, Inc. | Enzyme detection technique |
| US7704702B2 (en) * | 2006-08-10 | 2010-04-27 | Inverness Medical Switzerland Gmbh | Test strip for lateral flow assays |
| EP2245177B1 (en) * | 2008-02-19 | 2015-05-13 | Becton Dickinson and Company | Systems and methods for identifying a culture as positive for microorganisms with high confidence |
| EP2313527A4 (en) * | 2008-07-15 | 2012-11-21 | Rapid Pathogen Screening Inc | Lateral flow NUCLEIC DETECTOR |
| KR100946566B1 (ko) | 2009-11-18 | 2010-03-11 | 주식회사 인포피아 | 측방 유동 면역 분석 디바이스 |
| US8202693B2 (en) * | 2009-11-24 | 2012-06-19 | Omega Bio-Tek, Inc. | Method of isolation of nucleic acids |
-
2012
- 2012-07-20 PH PH1/2014/500147A patent/PH12014500147A1/en unknown
- 2012-07-20 BR BR112014001544-9A patent/BR112014001544B1/pt active IP Right Grant
- 2012-07-20 CN CN201810054519.6A patent/CN108107211B/zh active Active
- 2012-07-20 US US13/554,417 patent/US9575056B2/en active Active
- 2012-07-20 MX MX2014000830A patent/MX354260B/es active IP Right Grant
- 2012-07-20 WO PCT/US2012/047625 patent/WO2013016200A1/en active Application Filing
- 2012-07-20 CN CN201280043565.7A patent/CN103842523A/zh active Pending
- 2012-07-20 JP JP2014521831A patent/JP6067701B2/ja active Active
- 2012-07-20 KR KR1020147003992A patent/KR101751205B1/ko active Active
- 2012-07-20 CA CA2841976A patent/CA2841976C/en active Active
- 2012-07-20 EP EP12817120.4A patent/EP2734647B1/en active Active
-
2014
- 2014-01-21 ZA ZA2014/00481A patent/ZA201400481B/en unknown
-
2017
- 2017-02-21 US US15/438,286 patent/US10048251B2/en active Active
-
2018
- 2018-01-26 PH PH12018500220A patent/PH12018500220B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH12018500220B1 (en) | 2021-04-14 |
| MX2014000830A (es) | 2014-07-09 |
| CA2841976A1 (en) | 2013-01-31 |
| CN103842523A (zh) | 2014-06-04 |
| KR101751205B1 (ko) | 2017-06-27 |
| JP2014525744A (ja) | 2014-10-02 |
| JP6067701B2 (ja) | 2017-01-25 |
| WO2013016200A1 (en) | 2013-01-31 |
| BR112014001544A2 (pt) | 2017-06-13 |
| KR20140072023A (ko) | 2014-06-12 |
| US20170199177A1 (en) | 2017-07-13 |
| US10048251B2 (en) | 2018-08-14 |
| US9575056B2 (en) | 2017-02-21 |
| CN108107211A (zh) | 2018-06-01 |
| US20130022969A1 (en) | 2013-01-24 |
| CA2841976C (en) | 2021-05-11 |
| PH12014500147A1 (en) | 2014-03-31 |
| PH12018500220A1 (en) | 2018-10-15 |
| BR112014001544B1 (pt) | 2020-10-06 |
| CN108107211B (zh) | 2020-06-09 |
| EP2734647A4 (en) | 2015-06-03 |
| EP2734647A1 (en) | 2014-05-28 |
| EP2734647B1 (en) | 2018-10-17 |
| ZA201400481B (en) | 2014-11-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |