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NL2009597A - Accommodating intraocular lenses with artificial pupil. - Google Patents

Accommodating intraocular lenses with artificial pupil. Download PDF

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Publication number
NL2009597A
NL2009597A NL2009597A NL2009597A NL2009597A NL 2009597 A NL2009597 A NL 2009597A NL 2009597 A NL2009597 A NL 2009597A NL 2009597 A NL2009597 A NL 2009597A NL 2009597 A NL2009597 A NL 2009597A
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NL
Netherlands
Prior art keywords
construction
eye
lens
elements
combination
Prior art date
Application number
NL2009597A
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Dutch (nl)
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NL2009597C2 (en
Inventor
Aleksey Nikolaevich Simonov
Michiel Christiaan Rombach
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Akkolens Int Bv
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Priority to NL2009597A priority Critical patent/NL2009597C2/en
Publication of NL2009597A publication Critical patent/NL2009597A/en
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Publication of NL2009597C2 publication Critical patent/NL2009597C2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1648—Multipart lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1629—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing longitudinal position, i.e. along the visual axis when implanted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1632—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing radial position, i.e. perpendicularly to the visual axis when implanted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2002/1696—Having structure for blocking or reducing amount of light transmitted, e.g. glare reduction

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Description

Accommodating intraocular lenses with artificial pupil
Intraocular lenses (also: IOLs) are implanted in the eye by a surgeon to replace the natural lens in the eye. Monofocal IOLs only correct for the basic refraction of the eye, while accommodating IOLs also include a lens of variable focusing power to also restore accommodation of the eye.
The present invention, as described in this document discloses accommodating IOL constructions to be implanted in the human eye by eye surgery which constructions comprise at least one artificial lens and at least one, generally only one, artificial pupil. The diameter of the artificial pupil is adapted such that the eye is protected from stray light under intense light conditions when the natural pupil has a wide diameter and such that the artificial pupil does not interfere with the light beam when the natural pupil is of a smaller diameter. The diameter of the natural pupil of the eye varies between individuals, generally within the range of 2.5mm, in high light, to about 6-7mm, in low light. The natural lens is positioned behind the pupil in the eye and has a diameter of about 8-9mm which diameter safely exceeds the pupil diameter so that no stray light will pass around the lens. Stray light can spoil the image on the retina by, for example, reduction of contrast. However, IOLs have to be manufactured to diameters smaller than 9mm because, firstly, the haptics, the anchors which position the IOL in the eye, require space, and, secondly, desired small sizes of lenses so that surgery can be performed through small surgical incisions. Accommodating IOLs are generally even smaller because the driving mechanism of the lens also requires space which has to be deducted from the diameter of the optics.
Figure 1 shows a lens element 1, a pupil element 2 and a combination element 3, which elements can be combined in different combinations in an accommodating intraocular lens constructions as disclosed in the present document. The lens-element 1, comprises only an artificial lens 4, the pupil-element 2, comprises only the peripheral opaque section 6, to restrict the peripheral light beam, which section also forms the central translucent pupil 5, and the combination-element 3, comprises both the artificial lens 4, as well as the opaque section 6 and pupil 5.
Figure 2 depicts an example of an accommodating lens. This figure shows an accommodating lens with artificial pupil 7, with two connected combination elements 8 and 9, connected by a flexible connection 10, and with two haptics 11, to position the construction in the eye and additional components adapted to transfer movement of driving means, a component in the eye driving accommodation, to at least one lens-element, with, in this example, the two artificial lenses being cubic lenses which, in combination, form a lens with variable focusing power.
Figure 3 depicts an embodiment of an accommodating lens in the eye. This figure shows an eye 12, with the optical axis 13, the cornea 14, the iris 15 and the natural pupil 16, flexibly connected lens-elements with cubic artificial lenses 17 and 18, positioned in the sulcus 19, and driven by the ciliary muscle 20, and, separate a pupil-element 21, with the artificial pupil 22, in this example positioned in the capsular bag 23, with the construction projecting an image on the retina 24.
Such accommodating intraocular lens construction, including artificial lens and an artificial pupil, is intended to replace the natural lens of the eye which natural lens is removed by an eye surgeon because of, for example, cataracts. The lens construction (also: construction) comprises a combination of at least two elements. A simple embodiment of an element is, for example, a flat base plate to which optical surfaces, pupils or additional components can be fitted. The combination of elements should include at least two elements of the lens-element type, meaning that each of the elements comprises at least one artificial lens to modulate the light beam. Modulation is used here in a wide sense and modulation is not restricted to focusing modulation only. For example, an artificial lens can also provide cubic modulation such that two of such artificial lenses can provide a lens for variable focusing. Additionally, the construction includes additional components adapted to position the construction in the eye. The construction also includes additional components to transfer movement from driving means, a component in the eye driving accommodation, to at least one lens-element. In contrast to any other accommodating IOL, the lenses disclosed in the present document also comprise at least one pupil-element of the pupil-element type, meaning an element comprising an artificial pupil adapted to restrict the periphery of the light beam, which pupil-element is included in the combination of elements.
An artificial lens and an artificial pupil can be combined on an element of the combination-element type, meaning an element comprising a combination of at least one artificial lens and at least one artificial pupil, which can be, in its most simple embodiment, an artificial lens surrounded by an opaque, for example, black, periphery. So, the construction can comprise a combination of two elements of which at least one element is a combination-element.
Alternatively, the construction can comprise, for example, a combination of three elements, with at least two of the elements a lens-elements and at least one element a pupil-element. In such construction the lens-elements are likely to be connected with their combination provide the lens for variable focusing power and the third element a, for example, combination element with the artificial pupil and, for example, a lens of fixed optical power for correction of refractive error of the eye. Other combinations of elements can be designed and the construction can comprise any combination of multiple elements including any combination of any type of said elements.
The elements of the construction can be mechanically connected to other elements of the construction, as in, for example, W02005084587, WO2011053143 and US2005324673, which construction of connected elements are generally positioned in a single section of the eye, for example in the capsular bag or, alternatively, in the sulcus of the eye. However, alternatively, at least one the elements of the construction can be mechanically separated from the other elements of the construction. Such one element of the construction can be adapted to be positioned in a section in the eye which section differs from the section in which at least one of the other elements of the construction is adapted to be positioned. For example, the construction can include lens-elements with artificial lenses forming, in combination, a variable focusing lens, as in, for example, W02005084587 or US2005324673, which variable lenses are positioned in the sulcus or capsular bag, respectively, and which variable lenses can be combined with a separate pupil-element which can be positioned in the capsular bag or in the sulcus.
So, the construction can include at least one element of the construction adapted to be positioned in the posterior chamber of the eye, or, alternatively, the construction can include at least one element of the construction adapted to be positioned in the anterior chamber of the eye, with at least one element of the construction adapted to be positioned in the sulcus of the eye, or, alternatively, with at least one element of the construction is adapted to be positioned in the capsular bag of the eye, with the combinations not restricted to these combinations.
The construction can include, to provide a lens of variable focusing power, with at least two elements which each comprise an artificial lens adapted to modulate the light beam such that a combination of at least two such artificial lenses provide a lens of variable focusing power of which the degree of focusing power depends on the position of one element relative to at least one other element. The position of at least one of the elements can be a position in a direction along the optical axis, as in, for example, US2005324673, which employs two basically spherical optics. Alternatively, the position can be a position in a plane perpendicular to the optical axis as in, for example, W02005084587, with two shifting elements, or, alternatively, rotating elements, which employs two basically cubic optics. Alternatively, the position can be a combination of a position along the axis and a position perpendicular to the axis as in, for example, WO2011053143, which employs shift in position along the optical axis and in a plane perpendicular to the optical axis.
The construction generally also comprises at least one haptic, meaning at least one additional component adapted to position, to anchor, the elements in the eye, as do virtually all IOLs to date. The construction generally also includes at least one additional component adapted to transfer movement from driving means, a component in the eye driving accommodation, to at least one lens-element with the driving means being a natural component of the eye for natural drive of accommodation, for example, the ciliary muscle of the eye, which is the driving means for all accommodating lenses implanted to date. However, in the near future the natural driving means can well be replaced by artificial driving means implanted in the eye, for example, one or more micro-electro-mechanical systems.
The construction generally comprises at least one artificial lens for correction of refraction, meaning a lens adapted to provide correction of refractive error of the eye which error remains after surgical removal of the natural lens in addition to a lens for variable focusing power.
In more advanced embodiments the construction can include, firstly, a combination of at least two artificial lenses adapted to provide variable focusing power to correct variable defocus of the eye, to restore accommodation of the eye. The construction can also include, secondly, a combination of at least two artificial lenses with the combination adapted to provide variable optical power to correct for at least one variable undesired aberration. Such aberration can be generated by the eye itself, for example, undesired spherical aberration. However, such aberration can also be generated by the construction itself, for example, undesired variable tilt or undesired variable coma, which aberrations can be, simultaneously, variably corrected for by optics as disclosed in US2010094413. The construction must, thirdly, also include said fixed artificial lens for correction of refraction error, and, the construction can include a fixed artificial lens of fixed optical power to correct at least one additional fixed optical error, for example, astigmatism.

Claims (21)

1. Accommoderende intra-oculaire lensconstructie omvattende: - een combinatie van ten minste twee elementen met inbegrip van ten minste twee lenselementen, hetgeen betekent dat elk van de elementen ten minste één kunstmatige lens omvat die is ingericht om de lichtbundel te moduleren, - waarbij de constructie is voorzien van extra componenten die zijn ingericht om de constructie in het oog te positioneren en van extra componenten die zijn ingericht om beweging van stuurmiddelen over te brengen op ten minste één lenselement, waarbij stuurmiddelen ten minste één component in het oog omvatten, met het kenmerk dat de combinatie eveneens ten minste één pupilelement omvat, zijnde een element dat een kunstmatige pupil omvat die is ingericht om de omtrekrand van de lichtbundel te beperken.A accommodating intraocular lens construction comprising: - a combination of at least two elements including at least two lens elements, which means that each of the elements comprises at least one artificial lens adapted to modulate the light beam, - wherein structure is provided with additional components adapted to position the structure in the eye and with additional components adapted to transfer movement of control means to at least one lens element, wherein control means comprise at least one component in the eye, characterized in that the combination also comprises at least one pupil element, being an element comprising an artificial pupil that is adapted to limit the peripheral edge of the light beam. 2. Constructie volgens conclusie 1, waarbij de constructie een combinatie omvat van twee elementen, met het kenmerk dat de combinatie ten minste één combinatie-element omvat, zijnde een element dat een combinatie van ten minste één kunstmatige lens en ten minste één kunstmatige pupil omvat.A structure as claimed in claim 1, wherein the structure comprises a combination of two elements, characterized in that the combination comprises at least one combination element, being an element comprising a combination of at least one artificial lens and at least one artificial pupil . 3. Constructie volgens conclusie 1, omvattende een combinatie van drie elementen, met het kenmerk dat ten minste twee van de elementen lenselementen zijn en ten minste één element een pupilelement is.3. Construction as claimed in claim 1, comprising a combination of three elements, characterized in that at least two of the elements are lens elements and at least one element is a pupil element. 4. Constructie volgens de één van de conclusies 1-3, omvattende een combinatie van meervoudige elementen, met het kenmerk dat de combinatie elke combinatie omvat van elk type elementen.Construction according to any one of claims 1-3, comprising a combination of multiple elements, characterized in that the combination comprises any combination of any type of elements. 5. Constructie volgens de één van de conclusies 1-4, met het kenmerk dat de elementen van de constructie mechanisch zijn verbonden met alle andere elementen van de constructie.A construction as claimed in any one of claims 1-4, characterized in that the elements of the construction are mechanically connected to all other elements of the construction. 6. Constructie volgens één van de conclusies 1-4, met het kenmerk dat ten minste één van de elementen van de constructie mechanisch is gescheiden van de andere elementen van de constructie.A construction as claimed in any one of claims 1-4, characterized in that at least one of the elements of the construction is mechanically separated from the other elements of the construction. 7. Constructie volgens conclusie 6, met het kenmerk, dat ten minste één element van de constructie is ingericht om te worden gepositioneerd in een deel van het oog, welk deel verschilt van het deel waar ten minste één van de andere elementen van de constructie is ingericht om in te worden gepositioneerd.A construction as claimed in claim 6, characterized in that at least one element of the construction is arranged to be positioned in a part of the eye, which part differs from the part where at least one of the other elements of the construction is arranged to be positioned in. 8. Constructie volgens conclusie 5, 6 of 7, met het kenmerk dat ten minste één element van de constructie is ingericht om te worden gepositioneerd in de achterste kamer van het oog.A structure as claimed in claim 5, 6 or 7, characterized in that at least one element of the structure is adapted to be positioned in the posterior chamber of the eye. 9. Constructie volgens conclusie 5, 6 of 7, met het kenmerk dat ten minste één element van de constructie is ingericht om te worden gepositioneerd in de voorste kamer van het oog.A structure as claimed in claim 5, 6 or 7, characterized in that at least one element of the structure is adapted to be positioned in the anterior chamber of the eye. 10. Constructie volgens conclusie 9, met het kenmerk dat ten minste één element van de constructie is ingericht om te worden gepositioneerd in de sulcus van het oog.A structure as claimed in claim 9, characterized in that at least one element of the structure is adapted to be positioned in the sulcus of the eye. 11. Constructie volgens conclusie 9, met het kenmerk dat ten minste één element van de constructie is ingericht om te worden gepositioneerd in de kapselzak van het oog.A structure as claimed in claim 9, characterized in that at least one element of the structure is adapted to be positioned in the capsule bag of the eye. 12. Constructie volgens de voorgaande conclusies, met het kenmerk dat ten minste twee elementen elk een kunstmatige lens omvatten die is ingericht om de lichtbundel zodanig te moduleren dat een combinatie van ten minste twee van dergelijke kunstmatige lenzen een lens verschaft met een variabel focusserend vermogen, waarbij de mate van focusserend vermogen afhangt van de positie van één element ten opzichte van ten minste één van de andere elementen.A construction as claimed in the preceding claims, characterized in that at least two elements each comprise an artificial lens which is adapted to modulate the light beam such that a combination of at least two of such artificial lenses provides a lens with a variable focusing power, wherein the degree of focusing power depends on the position of one element relative to at least one of the other elements. 13. Constructie volgens conclusie 12, met het kenmerk dat de positie van één element ten opzichte van ten minste één ander element een positie is in een richting langs de optische as.A construction as claimed in claim 12, characterized in that the position of one element relative to at least one other element is a position in a direction along the optical axis. 14. Constructie volgens conclusie 12, met het kenmerk dat de positie van één element ten opzichte van ten minste één ander element een positie is in een vlak loodrecht op de optische as.A construction as claimed in claim 12, characterized in that the position of one element relative to at least one other element is a position in a plane perpendicular to the optical axis. 15. Constructie volgens conclusie 12, met het kenmerk dat de positie van één element ten opzichte van ten minste één ander element een combinatie is van een positie in een richting langs de optische as en een positie in een vlak loodrecht op de optische as.A construction as claimed in claim 12, characterized in that the position of one element relative to at least one other element is a combination of a position in a direction along the optical axis and a position in a plane perpendicular to the optical axis. 16. Constructie volgens één van de conclusies 1-15, omvattende ten minste één extra component, die is ingericht om beweging over te brengen van stuurmiddelen, zijnde een component in het oog die de accommodatie stuurt, naar ten minste één lenselement, met het kenmerk dat de stuurmiddelen een natuurlijke component van het oog zijn voor het natuurlijke aansturen van de accommodatie.A construction as claimed in any one of claims 1-15, comprising at least one additional component, which is adapted to transmit movement from control means, being a component in the eye that controls the accommodation, to at least one lens element, characterized in that the steering means are a natural component of the eye for the natural control of the accommodation. 17. Constructie volgens conclusie 16, met het kenmerk dat de natuurlijke component de ciliaire spier van het oog is.A construction as claimed in claim 16, characterized in that the natural component is the ciliary muscle of the eye. 18. Constructie volgens één van de conclusies 1-15, omvattende ten minste één extra component die is ingericht om beweging over te brengen van stuurmiddelen, zijnde een component in het oog die de accommodatie stuurt, naar ten minste één lenselement, met het kenmerk dat de stuurmiddelen een kunstmatige component zijn die in het oog is geïmplanteerd voor het kunstmatig aansturen van de accommodatie.A construction as claimed in any one of claims 1-15, comprising at least one additional component adapted to transmit movement from control means, being a component in the eye that controls the accommodation, to at least one lens element, characterized in that the control means are an artificial component implanted in the eye for artificially controlling the accommodation. 19. Constructie volgens conclusie 18, met het kenmerk dat de kunstmatige component ten minste één micro-elektromechanisch systeem is.A construction as claimed in claim 18, characterized in that the artificial component is at least one micro-electromechanical system. 20. Constructie volgens één van de conclusies 1-16, met het kenmerk dat de constructie ten minste één kunstmatige lens omvat voor het corrigeren van refractie, hetgeen een lens representeert die is ingericht om een refractiefout van het oog te corrigeren, welke fout na een chirurgische verwijdering van de natuurlijke lens blijvend is.A construction as claimed in any one of claims 1-16, characterized in that the construction comprises at least one artificial lens for correcting refraction, which represents a lens adapted to correct a refractive error of the eye, which error after a surgical removal of the natural lens is permanent. 21. Constructie volgens één van de conclusies 1 tot en met 17, met het kenmerk dat de constructie is voorzien van een combinatie van ten minste twee kunstmatige lenzen, die is ingericht om een variabel focusserend vermogen te verschaffen om variabele defocussering van het oog te corrigeren om de accommodatie van het oog te herstellen, van een combinatie van ten minste twee kunstmatige lenzen, waarbij de combinatie is ingericht om een variabel optisch vermogen te verschaffen om ten minste één variabele ongewenste afwijking te corrigeren, en bovendien van ten minste één kunstmatige lens met een vast optisch vermogen om een vaste brekingsfout van het oog te corrigeren, en bovendien van ten minste één extra kunstmatige lens met een vast optisch vermogen die is ingericht om ten minste één extra vaste optische fout te corrigeren.A construction as claimed in any one of claims 1 to 17, characterized in that the construction is provided with a combination of at least two artificial lenses, which is arranged to provide variable focusing power to correct variable defocusing of the eye to restore the accommodation of the eye, of a combination of at least two artificial lenses, the combination being arranged to provide a variable optical power to correct at least one variable unwanted aberration, and furthermore of at least one artificial lens with a fixed optical power to correct a fixed refractive error of the eye, and furthermore of at least one additional artificial lens with a fixed optical power adapted to correct at least one additional fixed optical error.
NL2009597A 2011-10-11 2012-10-09 Accommodating intraocular lenses with artificial pupil. NL2009597C2 (en)

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NL2007571 2011-10-11
NL2007571 2011-10-11
NL2009597A NL2009597C2 (en) 2011-10-11 2012-10-09 Accommodating intraocular lenses with artificial pupil.
NL2009597 2012-10-09

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NL2009597C2 NL2009597C2 (en) 2014-09-04

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6357875B1 (en) * 1994-12-08 2002-03-19 Herrick Family Limited Partnership Artificial lens including a lens system having eccentric axes for use in an eye having an enlarged pupil and method
WO2003015669A1 (en) * 2001-08-21 2003-02-27 Nulens Ltd. Accommodating lens assembly
WO2003017873A1 (en) * 2001-08-31 2003-03-06 Ehud Assia Implantable intraocular accommodative addition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6357875B1 (en) * 1994-12-08 2002-03-19 Herrick Family Limited Partnership Artificial lens including a lens system having eccentric axes for use in an eye having an enlarged pupil and method
WO2003015669A1 (en) * 2001-08-21 2003-02-27 Nulens Ltd. Accommodating lens assembly
WO2003017873A1 (en) * 2001-08-31 2003-03-06 Ehud Assia Implantable intraocular accommodative addition

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