NL300856I2 - - Google Patents

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Info

Publication number: NL300856I2
Authority: NL; Netherlands
Prior art keywords: nucleotides; splice; polynucleotide; altered; replaced
Prior art date: 2004-06-18

Application number

NL300856C

Other languages

English (en)

Original Assignee

Molmed Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-06-18

Filing date

2016-12-29

Publication date

2017-04-20

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32750189&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL300856(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2016-12-29 Application filed by Molmed Spa filed Critical Molmed Spa

2017-04-20 Publication of NL300856I2 publication Critical patent/NL300856I2/nl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
- C12N9/1211—Thymidine kinase (2.7.1.21)

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Immunology (AREA)
Oncology (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Vascular Medicine (AREA)
Pulmonology (AREA)
Tropical Medicine & Parasitology (AREA)
Transplantation (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)

NL300856C 2004-06-18 2016-12-29 NL300856I2 (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0413702.2A GB0413702D0 (en)	2004-06-18	2004-06-18	Thymidine kinase
PCT/IB2005/002358 WO2005123912A2 (en)	2004-06-18	2005-06-17	Thymidine kinase

Publications (1)

Publication Number	Publication Date
NL300856I2 true NL300856I2 (nl)	2017-04-20

Family

ID=32750189

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL300856C NL300856I2 (nl)	2004-06-18	2016-12-29

Country Status (20)

Country	Link
US (5)	US8357788B2 (nl)
EP (1)	EP1781789B1 (nl)
JP (1)	JP5091669B2 (nl)
KR (1)	KR101337210B1 (nl)
CN (1)	CN101010428B (nl)
AT (1)	ATE520779T1 (nl)
AU (1)	AU2005254807B2 (nl)
CA (1)	CA2569304C (nl)
CY (2)	CY1111925T1 (nl)
DK (1)	DK1781789T3 (nl)
ES (1)	ES2372022T3 (nl)
GB (1)	GB0413702D0 (nl)
HU (1)	HUS1600064I1 (nl)
IL (2)	IL179660A (nl)
LT (1)	LTC1781789I2 (nl)
NL (1)	NL300856I2 (nl)
PL (1)	PL1781789T3 (nl)
PT (1)	PT1781789E (nl)
SI (1)	SI1781789T1 (nl)
WO (1)	WO2005123912A2 (nl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0413702D0 (en)	2004-06-18	2004-07-21	Molmed Spa	Thymidine kinase
US20140248695A1 (en)	2011-10-05	2014-09-04	MolMed, S.p.A.	Viral Vectors Purification System
CA3087175A1 (en)	2017-12-28	2019-07-04	Bionoxx Inc.	An oncolytic virus vector comprising c-terminally truncated herpes simplex virus-thymidine kinase (hsv-tk), compositions and methods of use thereof
US11157042B1 (en)	2018-03-28	2021-10-26	Douglas Patton	Systems and methods for interaction of wearable communication devices
CN112204133B (zh)	2018-05-30	2024-04-19	格雷克斯迪姆医疗私人有限公司	Car nk细胞
WO2020263059A1 (ko) *	2019-06-27	2020-12-30	주식회사 바이오녹스	안전성 및 항암효과가 개선된 항암바이러스
WO2025168661A1 (en)	2024-02-05	2025-08-14	Ospedale San Raffaele S.R.L.	Chimeric antigen receptor

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1990007936A1 (en)	1989-01-23	1990-07-26	Chiron Corporation	Recombinant therapies for infection and hyperproliferative disorders
ATE219519T1 (de) *	1989-01-23	2002-07-15	Chiron Corp	Rekombinanttherapien für infektionen und hyperproliferative störungen
US5631236A (en) *	1993-08-26	1997-05-20	Baylor College Of Medicine	Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk
IT1261847B (it)	1993-09-01	1996-06-03	San Romanello Centro Fond	Metodo per marcare cellule eucariote.
FR2712603B1 (fr)	1993-11-18	1996-02-09	Centre Nat Rech Scient	Virus recombinants, préparation et utilisation en thérapie génique.
WO1995030007A1 (en)	1994-05-02	1995-11-09	University Of Washington	Thymidine kinase mutants
FR2744731B1 (fr)	1996-02-09	1998-05-22	Rhone Poulenc Rorer Sa	Nouveaux variants de la thymidine kinase, sequences d'acides nucleiques correspondantes et leur utilisation en therapie genique
BR9707483A (pt) *	1996-02-09	1999-04-06	Rhone Poulenc Rorer Sa	Sequência de ácidos nucléicos que codificam para uma timidina quinase variante de uma timidina quinase selvagem variante de uma timidina quinase do vírus do herpes simplex de tipo 1 veículo de expressão vetor e composição farmacêutica
FR2751988B1 (fr)	1996-08-01	1998-09-11	Rhone Poulenc Rorer Sa	Nouveaux variants de la thymidine kinase, sequences d'acides nucleiques correspondantes et leur utilisation en therapie genique
JP2000510449A (ja)	1996-04-10	2000-08-15	南カリフォルニア大学	増殖性硝子体網膜症に対する遺伝子治療
WO1998004290A2 (en)	1996-07-26	1998-02-05	Perrine Susan P	Compositions comprising an inducing agent and an anti-viral agent for the treatment of blood, viral and cellular disorders
CA2306443A1 (en)	1997-10-14	1999-04-22	Darwin Molecular Corporation	Thymidine kinase mutants and fusion proteins having thymidine kinase and guanylate kinase activities
GB0008966D0 (en) *	2000-04-13	2000-05-31	Imp College Innovations Ltd	Vectors for gene therapy
CN1273587C (zh) *	2002-06-05	2006-09-06	上海新世界基因技术开发有限公司	疱疹病毒胸苷激酶突变体及其应用
EP1428886B1 (de)	2002-12-09	2009-08-05	Celltech GmbH Biotechnologie	Verbesserte retrovirale Vektoren für die Gentherapie
GB0413702D0 (en)	2004-06-18	2004-07-21	Molmed Spa	Thymidine kinase

2004
- 2004-06-18 GB GBGB0413702.2A patent/GB0413702D0/en not_active Ceased
2005
- 2005-06-17 WO PCT/IB2005/002358 patent/WO2005123912A2/en active Application Filing
- 2005-06-17 PL PL05766582T patent/PL1781789T3/pl unknown
- 2005-06-17 SI SI200531385T patent/SI1781789T1/sl unknown
- 2005-06-17 EP EP05766582A patent/EP1781789B1/en not_active Expired - Lifetime
- 2005-06-17 JP JP2007516075A patent/JP5091669B2/ja not_active Expired - Fee Related
- 2005-06-17 AU AU2005254807A patent/AU2005254807B2/en not_active Ceased
- 2005-06-17 CN CN2005800286686A patent/CN101010428B/zh not_active Expired - Fee Related
- 2005-06-17 ES ES05766582T patent/ES2372022T3/es not_active Expired - Lifetime
- 2005-06-17 KR KR1020077001055A patent/KR101337210B1/ko not_active Expired - Fee Related
- 2005-06-17 CA CA2569304A patent/CA2569304C/en not_active Expired - Fee Related
- 2005-06-17 US US11/629,962 patent/US8357788B2/en not_active Expired - Fee Related
- 2005-06-17 PT PT05766582T patent/PT1781789E/pt unknown
- 2005-06-17 AT AT05766582T patent/ATE520779T1/de active
- 2005-06-17 DK DK05766582.0T patent/DK1781789T3/da active
2006
- 2006-11-28 IL IL179660A patent/IL179660A/en active IP Right Grant
2011
- 2011-05-24 IL IL213084A patent/IL213084A0/en unknown
- 2011-10-10 CY CY20111100964T patent/CY1111925T1/el unknown
2012
- 2012-08-31 US US13/601,174 patent/US8642311B2/en not_active Expired - Lifetime
2013
- 2013-12-10 US US14/101,704 patent/US9005945B2/en not_active Expired - Fee Related
2015
- 2015-04-01 US US14/676,696 patent/US10155052B2/en not_active Expired - Fee Related
2016
- 2016-12-28 LT LTPA2016047C patent/LTC1781789I2/lt unknown
- 2016-12-28 CY CY2016054C patent/CY2016054I2/el unknown
- 2016-12-29 NL NL300856C patent/NL300856I2/nl unknown
- 2016-12-30 HU HUS1600064C patent/HUS1600064I1/hu unknown
2018
- 2018-11-15 US US16/192,224 patent/US10314925B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO2005123912A2 (en)	2005-12-29
DK1781789T3 (da)	2011-11-28
US10155052B2 (en)	2018-12-18
IL179660A (en)	2012-12-31
KR20070032786A (ko)	2007-03-22
CN101010428A (zh)	2007-08-01
ES2372022T3 (es)	2012-01-13
CA2569304C (en)	2014-08-12
CA2569304A1 (en)	2005-12-29
US8357788B2 (en)	2013-01-22
HUS1600064I1 (hu)	2017-02-28
US20130028876A1 (en)	2013-01-31
EP1781789A2 (en)	2007-05-09
US20140178345A1 (en)	2014-06-26
IL213084A0 (en)	2011-07-31
WO2005123912A3 (en)	2006-05-04
SI1781789T1 (sl)	2012-03-30
CY2016054I1 (el)	2017-07-12
PL1781789T3 (pl)	2011-12-30
US20150231275A1 (en)	2015-08-20
PT1781789E (pt)	2011-10-20
US9005945B2 (en)	2015-04-14
US20190070312A1 (en)	2019-03-07
AU2005254807B2 (en)	2011-08-18
AU2005254807A1 (en)	2005-12-29
US8642311B2 (en)	2014-02-04
US20090130069A1 (en)	2009-05-21
CN101010428B (zh)	2013-10-02
EP1781789B1 (en)	2011-08-17
IL179660A0 (en)	2007-05-15
LTC1781789I2 (lt)	2018-10-10
KR101337210B1 (ko)	2013-12-06
CY2016054I2 (el)	2017-07-12
GB0413702D0 (en)	2004-07-21
JP5091669B2 (ja)	2012-12-05
HK1097881A1 (en)	2007-07-06
CY1111925T1 (el)	2015-11-04
LTPA2016047I1 (lt)	2017-01-25
ATE520779T1 (de)	2011-09-15
JP2008502342A (ja)	2008-01-31
US10314925B2 (en)	2019-06-11

Publication	Publication Date	Title
HUS1600064I1 (hu)	2017-02-28	Timidin kináz
DE112007002932T8 (de)	2009-11-26	Vierfarben DNA-Sequenzierung mittels Synthese unter Verwendung von abspaltbaren, reversiblen, fluoreszierenden Nucleotidterminatoren
WO2007119148A3 (en)	2008-02-28	Method providing efficient and flexible control signal for resource allocation
AU2003262906A8 (en)	2004-03-19	Bioreactors with multiple chambers
ATE538127T1 (de)	2012-01-15	6-disubstituierte bicyclische nukleinsäureanaloga
TW200630362A (en)	2006-09-01	(2-carboxamido)(3-amino)thiophene compounds
GT200500272A (es)	2006-06-06	2-anilinopirimidinas sustituidas como inhibidores de la quinasa del ciclo celular o del receptor de la tirosina quinasa, su preparacion y su uso como medicamentos
WO2008146745A1 (ja)	2008-12-04	新規なリゾホスファチジン酸アシル基転移酵素遺伝子
ATE542782T1 (de)	2012-02-15	Bauplatte
TW200510510A (en)	2005-03-16	Polyquinoline copolymer and organic electroluminescence element using the same
WO2006026238A3 (en)	2006-06-01	Rna interference in avians
DE602005015868D1 (de)	2009-09-17	Modulation der anzahl von pflanzenzellen
ATE497991T1 (de)	2011-02-15	Phosphitester enthaltende stabilisatorzusammensetzung
DE50300919D1 (de)	2005-09-08	Verwendung eines magnesiazirkoniasteins
SG136817A1 (en)	2007-11-29	Keyboard for use in computer system
TW200834278A (en)	2008-08-16	Multiplier-divider with error compensation function
DE602007013084D1 (de)	2011-04-21	Neues markiertes oligonukleotid
ATE361081T1 (de)	2007-05-15	Verwendung von 5-substituierten nukleosiden zur verstärkung der apoptotischen wirkung von zytostatika
DK1478664T3 (da)	2011-01-31	Vævsspecifik ekspression
FR2853906B1 (fr)	2006-04-14	N-desoxyribosyltransferases de lactobacilles, sequences nucleotidiques correspondantes et leurs applications
ATE443929T1 (de)	2009-10-15	Enzymatische brennstoffzelle
AU302895S (en)	2005-08-26	A jacket
ITCR20030012A1 (it)	2005-04-03	Digestore anaerobico.
TR200606198U (tr)	2006-12-21	Küçük parçalı görünümlü seramik karo
TW568145U (en)	2003-12-21	Lock able to change keys thereof