[go: up one dir, main page]

NO20016341L - Inhibitorer for integrinet <alfa>v<beta>6 - Google Patents

Inhibitorer for integrinet <alfa>v<beta>6

Info

Publication number
NO20016341L
NO20016341L NO20016341A NO20016341A NO20016341L NO 20016341 L NO20016341 L NO 20016341L NO 20016341 A NO20016341 A NO 20016341A NO 20016341 A NO20016341 A NO 20016341A NO 20016341 L NO20016341 L NO 20016341L
Authority
NO
Norway
Prior art keywords
asp
leu
arg
xer
phe
Prior art date
Application number
NO20016341A
Other languages
English (en)
Norwegian (no)
Other versions
NO20016341D0 (no
Inventor
Alfred Jonczyk
Beate Diefenbach
Ulrich Groth
Gunther Zischinsky
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20016341D0 publication Critical patent/NO20016341D0/no
Publication of NO20016341L publication Critical patent/NO20016341L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02Linear peptides containing at least one abnormal peptide link
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO20016341A 1999-06-26 2001-12-21 Inhibitorer for integrinet <alfa>v<beta>6 NO20016341L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19929410A DE19929410A1 (de) 1999-06-26 1999-06-26 Inhibitoren des Integrins avß6
PCT/EP2000/005404 WO2001000660A1 (fr) 1999-06-26 2000-06-13 INHIBITEURS DE L'INTEGRINE αVβ¿6?

Publications (2)

Publication Number Publication Date
NO20016341D0 NO20016341D0 (no) 2001-12-21
NO20016341L true NO20016341L (no) 2002-02-25

Family

ID=7912712

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20016341A NO20016341L (no) 1999-06-26 2001-12-21 Inhibitorer for integrinet <alfa>v<beta>6

Country Status (17)

Country Link
EP (1) EP1189930A1 (fr)
JP (1) JP2003503422A (fr)
KR (1) KR20020015704A (fr)
CN (1) CN1358195A (fr)
AR (1) AR024472A1 (fr)
AU (1) AU771099B2 (fr)
BR (1) BR0011954A (fr)
CA (1) CA2377224A1 (fr)
CZ (1) CZ20014484A3 (fr)
DE (1) DE19929410A1 (fr)
HU (1) HUP0201729A3 (fr)
MX (1) MXPA01013247A (fr)
NO (1) NO20016341L (fr)
PL (1) PL352374A1 (fr)
SK (1) SK18722001A3 (fr)
WO (1) WO2001000660A1 (fr)
ZA (1) ZA200200673B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6972296B2 (en) 1999-05-07 2005-12-06 Encysive Pharmaceuticals Inc. Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
CA2515127A1 (fr) 2003-02-06 2004-08-19 Alfred Jonczyk Sulfonamides peptidiques
GB0520068D0 (en) 2005-10-03 2005-11-09 Cancer Res Technology av peptide ligand
WO2008112004A2 (fr) 2006-08-03 2008-09-18 Astrazeneca Ab ANTICORPS DIRIGÉS CONTRE αVβ6 ET LEURS UTILISATIONS
EA201991102A1 (ru) * 2016-11-01 2019-09-30 Эрроухед Фармасьютикалс, Инк. Альфа-v бета-6 лиганды интегрина и варианты их применения
SG11202002967SA (en) 2017-11-01 2020-05-28 Arrowhead Pharmaceuticals Inc Integrin ligands and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2103139A1 (fr) * 1991-05-14 1992-11-15 George A. Heavner Inhibiteurs peptidiques de l'inflammation
DK1504764T3 (da) * 1997-08-08 2008-11-17 Univ California Behandling af leverfibrose med antistoffer mod alfa-V-beta-6-integrin
JP2002533064A (ja) * 1998-12-19 2002-10-08 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング インテグリンαvβ6阻害剤

Also Published As

Publication number Publication date
JP2003503422A (ja) 2003-01-28
HUP0201729A3 (en) 2005-01-28
SK18722001A3 (sk) 2002-05-09
HUP0201729A2 (en) 2002-08-28
ZA200200673B (en) 2003-04-24
CA2377224A1 (fr) 2001-01-04
AR024472A1 (es) 2002-10-02
AU6263000A (en) 2001-01-31
DE19929410A1 (de) 2000-12-28
WO2001000660A1 (fr) 2001-01-04
NO20016341D0 (no) 2001-12-21
AU771099B2 (en) 2004-03-11
CZ20014484A3 (cs) 2002-04-17
KR20020015704A (ko) 2002-02-28
MXPA01013247A (es) 2002-07-02
BR0011954A (pt) 2002-05-07
EP1189930A1 (fr) 2002-03-27
PL352374A1 (en) 2003-08-25
CN1358195A (zh) 2002-07-10

Similar Documents

Publication Publication Date Title
ES2680022T3 (es) Fragmentos peptídicos para inducir la síntesis de proteínas de la matriz extracelular
US5192746A (en) Cyclic cell adhesion modulation compounds
DE10075019I2 (de) Neue Proteine mit TNF-Hemmender Wirkung und ihre Herstellung.
CN101855235B (zh) 保护性皮肤护理四肽
CA2370289A1 (fr) Peptides inhibiteurs de l&#39;exocytose neuronale, compositions cosmetiques et pharmaceutiques les contenant
JP2006028195A (ja) フィブロネクチン及び関連コラーゲン−結合性タンパク質のペプチド阻害剤
KR940703854A (ko) 사람 쿠니즈형 프로테아제 저해제 변이체(a human kunitz-type protease inhibitor variant)
DK165988B (da) Modificerede egliner b og c, deres anvendelse som proteaseinhibitorer, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende de modificerede egliner b og c
WO2001005810A3 (fr) DERIVES PEPTIDIQUES CYCLIQUES SERVANT D&#39;INHIBITEURS DE L&#39;INTEGRINE αVβ¿6?
AR006517A1 (es) Polipeptido que alcanza un total de alrededor de 30 aminoacidos; sustancia, peptidomimetico y composicion farmaceutica resultantes; usos del polipeptidoy proceso para la sintesis del polipeptido.
ATE106449T1 (de) Hemmung des reaktionswegs für die n-ende-regel in lebenden zellen.
Ramage et al. Solid phase peptide synthesis of ubiquitin
NO20016341L (no) Inhibitorer for integrinet &lt;alfa&gt;v&lt;beta&gt;6
CA2026376C (fr) Peptides anticoagulants
DE68916850T2 (de) Antikoagulierende Peptid-Alkohole.
AU641215B2 (en) Stabilized sulfonate, sulfate, phosphonate and phosphate derivatives of hirudin
US5192747A (en) Anticoagulant peptides
US5039790A (en) Bioactive fragment of interleukin-1-B that has antagonistic activity
RU99116976A (ru) Миелопептиды и их терапевтическое использование
MXPA04007170A (es) Peptidos sinteticos y usos de los mismos para la prevencion y la terapia de metastasis e invasion de cancer.
AU2676399A (en) Novel cystine knot protein and materials and methods for making it
RU95120588A (ru) Циклогексапептиды, их смеси, способ их получения и применения
JPH08269090A (ja) 新規ぺプチド
Seyer et al. Covalent structure of collagen: Amino acid sequence of three cyanogen bromide-derived peptides from human α1 (V) collagen chain
Sheh et al. Studies of the synthesis, immunology, and cytotoxicity of a cyclic octapeptide corresponding to TNF-. alpha.-(59-66)

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application