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NO20032663L - Kombinatriske biblioteker av proteiner med scaffoldstrukturen til C-type lektinliknende domener - Google Patents

Kombinatriske biblioteker av proteiner med scaffoldstrukturen til C-type lektinliknende domener

Info

Publication number
NO20032663L
NO20032663L NO20032663A NO20032663A NO20032663L NO 20032663 L NO20032663 L NO 20032663L NO 20032663 A NO20032663 A NO 20032663A NO 20032663 A NO20032663 A NO 20032663A NO 20032663 L NO20032663 L NO 20032663L
Authority
NO
Norway
Prior art keywords
ctlds
libraries
tetranectin
domains
type lectin
Prior art date
Application number
NO20032663A
Other languages
English (en)
Norwegian (no)
Other versions
NO20032663D0 (no
Inventor
Hans Christian Thogersen
Michael Etzerodt
Thor Las Holtet
Niels Jonas Heilskov Graversen
Original Assignee
Anaphore Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anaphore Inc filed Critical Anaphore Inc
Publication of NO20032663D0 publication Critical patent/NO20032663D0/no
Publication of NO20032663L publication Critical patent/NO20032663L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20032663A 2000-12-13 2003-06-12 Kombinatriske biblioteker av proteiner med scaffoldstrukturen til C-type lektinliknende domener NO20032663L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200001872 2000-12-13
US27209801P 2001-02-28 2001-02-28
PCT/DK2001/000825 WO2002048189A2 (fr) 2000-12-13 2001-12-13 Échantillothèques combinatoires de protéines présentant la structure en échafaudage des domaines lectonoïdes de type c

Publications (2)

Publication Number Publication Date
NO20032663D0 NO20032663D0 (no) 2003-06-12
NO20032663L true NO20032663L (no) 2003-07-17

Family

ID=26068925

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20032663A NO20032663L (no) 2000-12-13 2003-06-12 Kombinatriske biblioteker av proteiner med scaffoldstrukturen til C-type lektinliknende domener

Country Status (14)

Country Link
US (2) US8017559B2 (fr)
EP (2) EP1341912B1 (fr)
JP (1) JP4493271B2 (fr)
KR (1) KR100865602B1 (fr)
CN (1) CN100580084C (fr)
AT (1) ATE431851T1 (fr)
AU (2) AU2002221568B2 (fr)
BR (1) BR0116138A (fr)
CA (1) CA2430953A1 (fr)
DE (1) DE60138764D1 (fr)
DK (1) DK1341912T3 (fr)
NO (1) NO20032663L (fr)
NZ (1) NZ526312A (fr)
WO (1) WO2002048189A2 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60138764D1 (de) 2000-12-13 2009-07-02 Anaphore Inc Methode zur identifikation und isolation von peptide die andere moleküle binden aus kombinatorische proteinbibliotheken mit einer c-typ lectin-ähnlichen domäne als gerüststruktur
AU2003239777A1 (en) * 2002-07-05 2004-01-23 Borean Pharma A/S Multimerised growth hormone fusion proteins
WO2004018513A1 (fr) 2002-08-20 2004-03-04 Summit Glycoresearch Corporation Utilisation d'une banque de lectines pour distinguer des glycoproteines ou des cellules, analyser le serum ou des cellules ou fractionner des glycoproteines ou des cellules
AU2003277828B2 (en) 2002-10-29 2009-06-04 Anaphore, Inc. Trimeric binding proteins for trimeric cytokines
WO2005047511A2 (fr) * 2003-11-06 2005-05-26 Genencor International, Inc. Expression bacterienne d'inhibiteurs de protease et variants de ceux-ci
US20100028995A1 (en) * 2004-02-23 2010-02-04 Anaphore, Inc. Tetranectin Trimerizing Polypeptides
WO2006053568A1 (fr) 2004-11-22 2006-05-26 Borean Pharma Aps Antagonistes du tnf
US7723477B2 (en) 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
CA2670471A1 (fr) 2006-11-22 2008-06-05 Adnexus, A Bristol-Myers Squibb R&D Company (A Delaware Corporation) Substances therapeutiques a base de proteines modifiees ciblees sur des recepteurs de tyrosine kinases, dont l'igf-ir
WO2009036349A1 (fr) * 2007-09-12 2009-03-19 Anaphore, Inc. Traitement à base de hsp70 pour maladies auto-immunitaires
CA2705160A1 (fr) * 2007-11-09 2009-05-14 Anaphore, Inc. Proteines de fusion de lectines liant le mannose pour un traitement de maladie
PE20091931A1 (es) 2008-05-22 2009-12-31 Bristol Myers Squibb Co Proteinas de dominio de armazon basadas en fibronectina multivalentes
US20130295106A1 (en) * 2008-09-26 2013-11-07 Oncomed Pharmaceuticals, Inc. Frizzled-Binding Agents And Uses Thereof
CN105079805A (zh) 2008-09-26 2015-11-25 昂考梅德药品有限公司 卷曲蛋白结合药剂及其应用
CN102317314A (zh) 2008-10-10 2012-01-11 阿纳福公司 结合trail-r1和trail-r2的多肽
US20110086806A1 (en) * 2009-10-09 2011-04-14 Anaphore, Inc. Polypeptides that Bind IL-23R
WO2011043834A1 (fr) * 2009-10-09 2011-04-14 Anphore, Inc Banques combinatoires basées sur le domaine lectine de type c
CN102686606A (zh) * 2009-10-09 2012-09-19 阿纳福公司 结合il-23r的多肽
WO2011074941A1 (fr) * 2009-12-15 2011-06-23 Universiti Malaya Méthode de criblage à haut débit d'inhibiteurs qui inhibent l'interaction d'une protéine de fixation avec des récepteurs cellulaires au moyen d'un affichage de phages recombinants
TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Ｗｎｔ拮抗劑及治療和篩選方法
NZ602700A (en) 2010-04-01 2014-10-31 Oncomed Pharm Inc Frizzled-binding agents and uses thereof
KR101294982B1 (ko) * 2011-12-09 2013-08-08 경북대학교 산학협력단 단백질 골격모듈을 포함하는 융합 폴리펩타이드 및 이를 이용한 목적 단백질에 특이적인 펩타이드 라이브러리 스크리닝 방법
EP2821489B1 (fr) * 2012-03-02 2017-02-22 Japan Science And Technology Agency Procédé de construction de molécule d'acide nucléique fonctionnelle, et combinaison d'acides nucléiques destinée à être utilisée dans ledit procédé
AU2013334790A1 (en) 2012-10-23 2015-04-30 Oncomed Pharmaceuticals, Inc. Methods of treating neuroendocrine tumors using Wnt pathway-binding agents
JP2016510411A (ja) 2013-02-04 2016-04-07 オンコメッド ファーマシューティカルズ インコーポレイテッド Ｗｎｔ経路インヒビターによる処置の方法およびモニタリング
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
WO2014139182A1 (fr) 2013-03-15 2014-09-18 Shenzhen Hightide Biopharmaceutical, Ltd. Compositions et méthodes d'utilisation de peptides de néogenèse d'îlots et d'analogues de ceux-ci
GB201311031D0 (en) * 2013-06-20 2013-08-07 Queen Mary & Westfield College Method
ES2969960T3 (es) 2014-10-01 2024-05-23 Medimmune Llc Método para conjugar un polipéptido
AR111963A1 (es) 2017-05-26 2019-09-04 Univ California Método y moléculas
CN113372428B (zh) * 2021-05-21 2022-07-08 广东食品药品职业学院 文昌鱼C型凝集素BjCTL4基因及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0639224B1 (fr) 1992-04-30 2000-06-28 Genentech, Inc. Variants du domaine lectine de la selectine
US5679548A (en) * 1993-02-02 1997-10-21 The Scripps Research Institute Methods for producing polypeptide metal binding sites and compositions thereof
KR100310739B1 (ko) * 1993-02-04 2002-05-30 알란 스코브 단백질재생을위한개선된방법
US6025485A (en) * 1997-02-14 2000-02-15 Arcaris, Inc. Methods and compositions for peptide libraries displayed on light-emitting scaffolds
DE69827507T2 (de) * 1997-06-11 2006-03-09 Borean Pharma A/S Trimerisierendes modul
EP0947582A1 (fr) * 1998-03-31 1999-10-06 Innogenetics N.V. Une structure polypeptidique utilisable comme un squelette
US6180343B1 (en) * 1998-10-08 2001-01-30 Rigel Pharmaceuticals, Inc. Green fluorescent protein fusions with random peptides
DE60138764D1 (de) 2000-12-13 2009-07-02 Anaphore Inc Methode zur identifikation und isolation von peptide die andere moleküle binden aus kombinatorische proteinbibliotheken mit einer c-typ lectin-ähnlichen domäne als gerüststruktur

Also Published As

Publication number Publication date
EP2105503B1 (fr) 2012-09-19
EP1341912A2 (fr) 2003-09-10
JP4493271B2 (ja) 2010-06-30
BR0116138A (pt) 2003-09-23
JP2004515245A (ja) 2004-05-27
US20070275393A1 (en) 2007-11-29
DE60138764D1 (de) 2009-07-02
WO2002048189A2 (fr) 2002-06-20
EP2105503A3 (fr) 2011-03-02
NO20032663D0 (no) 2003-06-12
CN100580084C (zh) 2010-01-13
US20120094873A1 (en) 2012-04-19
ATE431851T1 (de) 2009-06-15
CA2430953A1 (fr) 2002-06-20
CN1484698A (zh) 2004-03-24
KR20040018316A (ko) 2004-03-03
AU2002221568B2 (en) 2005-06-02
EP2105503A2 (fr) 2009-09-30
AU2156802A (en) 2002-06-24
NZ526312A (en) 2004-11-26
EP1341912B1 (fr) 2009-05-20
US8017559B2 (en) 2011-09-13
DK1341912T3 (da) 2009-09-21
KR100865602B1 (ko) 2008-10-27
WO2002048189A3 (fr) 2003-01-09

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Legal Events

Date Code Title Description
CREP Change of representative

Representative=s name: ZACCO NORWAY AS, POSTBOKS 2003 VIKA, 0125 OSLO, NO

FC2A Withdrawal, rejection or dismissal of laid open patent application