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NO20081934L - Diaryleterderivater som antitumor midler - Google Patents

Diaryleterderivater som antitumor midler

Info

Publication number
NO20081934L
NO20081934L NO20081934A NO20081934A NO20081934L NO 20081934 L NO20081934 L NO 20081934L NO 20081934 A NO20081934 A NO 20081934A NO 20081934 A NO20081934 A NO 20081934A NO 20081934 L NO20081934 L NO 20081934L
Authority
NO
Norway
Prior art keywords
group
formula
antitumor agents
ether derivatives
hydrogen atom
Prior art date
Application number
NO20081934A
Other languages
English (en)
Norwegian (no)
Inventor
Takashi Nakagawa
Hironori Matsuyama
Kenji Ohnishi
Hideki Takasu
Makoto Sakamoto
Kumi Higuchi
Keisuke Miyajima
Satoshi Yamada
Masaaki Motoyama
Yutaka Kojima
Koichi Yasumura
Takeshi Kodama
Shun Otsuji
Keizo Kan
Takumi Sumida
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NO20081934L publication Critical patent/NO20081934L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20081934A 2005-12-05 2008-04-23 Diaryleterderivater som antitumor midler NO20081934L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005351255 2005-12-05
PCT/JP2006/324610 WO2007066784A2 (fr) 2005-12-05 2006-12-04 Substance medicamenteuse

Publications (1)

Publication Number Publication Date
NO20081934L true NO20081934L (no) 2008-08-13

Family

ID=38051953

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081934A NO20081934L (no) 2005-12-05 2008-04-23 Diaryleterderivater som antitumor midler

Country Status (21)

Country Link
US (1) US8236826B2 (fr)
EP (1) EP1957073B1 (fr)
KR (1) KR101157004B1 (fr)
CN (1) CN101321529B (fr)
AR (1) AR056885A1 (fr)
AU (1) AU2006323700B2 (fr)
BR (1) BRPI0619349A2 (fr)
CA (1) CA2630468C (fr)
CY (1) CY1115171T1 (fr)
DK (1) DK1957073T3 (fr)
ES (1) ES2463450T3 (fr)
IL (1) IL191544A0 (fr)
MY (1) MY146514A (fr)
NO (1) NO20081934L (fr)
PL (1) PL1957073T3 (fr)
PT (1) PT1957073E (fr)
RU (1) RU2444362C2 (fr)
SI (1) SI1957073T1 (fr)
TW (1) TWI332838B (fr)
WO (1) WO2007066784A2 (fr)
ZA (1) ZA200804445B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100927563B1 (ko) 2004-08-06 2009-11-23 오쓰까 세이야꾸 가부시키가이샤 방향족 화합물
UA95978C2 (ru) * 2006-10-02 2011-09-26 Оцука Фармас'Ютікел Ко., Лтд. Ингибитор активации stat3/5
CN101597278B (zh) 2008-06-04 2013-04-17 中国中化股份有限公司 酰胺类化合物及其制备与应用
CN102223797A (zh) 2008-11-21 2011-10-19 高点制药有限责任公司 金刚烷基苯甲酰胺化合物
EP2423194B1 (fr) 2009-04-20 2014-04-16 Mitsubishi Tanabe Pharma Corporation Nouvel agoniste du récepteur béta de l'hormone thyroïdienne
AU2010306750B2 (en) 2009-10-15 2014-11-13 Children's Medical Center Corporation Sepiapterin reductase inhibitors for the treatment of pain
US8722663B2 (en) 2010-01-29 2014-05-13 Otsuka Pharmaceutical Co., Ltd. Di-substituted pyridine derivatives as anticancers
WO2012015715A1 (fr) 2010-07-27 2012-02-02 High Point Pharmaceuticals, Llc Dérivés de thiazol-2-ylamine substitués, compositions pharmaceutiques et procédés d'utilisation en tant que modulateurs de 11-bêta-hsd1
SI2624833T1 (sl) * 2010-10-04 2015-03-31 Otsuka Pharmaceutical Co., Ltd. Derivati 4-(metilaminofenoksi)piridin-3-il-benzamida za zdravljenje raka
WO2012090177A2 (fr) * 2010-12-30 2012-07-05 Lupin Limited Modulateurs des récepteurs cannabinoïdes
WO2013005168A2 (fr) * 2011-07-05 2013-01-10 Lupin Limited Modulateurs des récepteurs de cannabinoïdes
TW201329025A (zh) 2011-11-01 2013-07-16 Astex Therapeutics Ltd 醫藥化合物
CA2859842C (fr) 2012-03-14 2016-11-08 Sinochem Corporation Composes de diphenylamine substitues et leur utilisation en tant qu'agents antitumoraux
JP6066806B2 (ja) * 2012-04-03 2017-01-25 大塚製薬株式会社 医薬
EP3800183A1 (fr) 2013-02-19 2021-04-07 ONO Pharmaceutical Co., Ltd. Derives de l'uree comme composés inhibant trk
EP3043784B9 (fr) * 2013-09-09 2019-11-20 Peloton Therapeutics, Inc. Aryléthers et utilisations de ceux-ci
JP6616786B2 (ja) * 2014-05-19 2019-12-04 メリアル インコーポレイテッド 駆虫性化合物
TW201617314A (zh) * 2014-09-10 2016-05-16 第一三共股份有限公司 羧酸衍生物
CN107098884A (zh) * 2016-02-19 2017-08-29 中国科学院上海药物研究所 一类取代的氨基吡啶类化合物及其制备和用途
JP7444458B2 (ja) * 2018-09-21 2024-03-06 学校法人福岡大学 プリオン病治療薬
WO2023160638A1 (fr) * 2022-02-28 2023-08-31 Sironax Ltd. Modulateurs de rip1, préparations et utilisations associées

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629102A (fr) * 1961-03-29
US3715375A (en) * 1970-09-17 1973-02-06 Merck & Co Inc New diphenyl sulfones
NL7111711A (fr) 1970-09-17 1972-03-21
GB1494117A (en) 1974-11-02 1977-12-07 Bayer Ag Process for the preparation of acid amides
DE2707660C2 (de) * 1977-02-23 1985-12-19 Bayer Ag, 5090 Leverkusen Abspalter- und Diolrest enthaltende Diisocyanat-Addukte, ihre Herstellung und Verwendung
DE2707659A1 (de) * 1977-02-23 1978-08-24 Bayer Ag Selbstvernetzbare polyurethane
DE2812252A1 (de) * 1978-03-21 1979-10-04 Bayer Ag 1,2,4-triazol-blockierte polyisocyanate als vernetzer fuer lackbindemittel
US4978672A (en) * 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
EP0500495A3 (en) * 1991-02-21 1993-04-07 Ciba-Geigy Ag Thermosetting composition
ES2108855T3 (es) * 1992-07-21 1998-01-01 Ciba Geigy Ag Derivados de acido oxamico como agentes hipocolesteremicos.
EP0706508A1 (fr) 1993-06-30 1996-04-17 The Wellcome Foundation Limited Composes de diaryle contre l'atherosclerose
CA2223948A1 (fr) 1995-06-07 1996-12-19 Rui Han Retinoides de chalcone et leurs procedes d'utilisation
US6022884A (en) * 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
AU2723099A (en) 1998-02-06 1999-08-23 Byk Gulden Lomberg Chemische Fabrik Gmbh Tryptase inhibitors
ATE282607T1 (de) 1998-02-06 2004-12-15 Max Planck Gesellschaft Tryptase-inhibitoren
AR015733A1 (es) 1998-03-25 2001-05-16 Otsuka Pharma Co Ltd DERIVADO DE PIRIDINA, EL PRODUCTO Y LA COMPOSICIoN FARMACEUTICA QUE CONTIENE DICHO DERIVADO.
TWI245035B (en) 1998-06-26 2005-12-11 Ono Pharmaceutical Co Amino acid derivatives and a pharmaceutical composition comprising the derivatives
KR100682276B1 (ko) * 1998-07-24 2007-02-28 데이진 가부시키가이샤 안트라닐산 유도체
EP1140840B1 (fr) * 1999-01-13 2006-03-22 Bayer Pharmaceuticals Corp. Diphenylurees a substituants -g(v)-carboxyaryles, inhibitrices de kinase raf
US20020065296A1 (en) * 1999-01-13 2002-05-30 Bayer Corporation Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors
AU2871900A (en) 1999-02-04 2000-08-25 Millennium Pharmaceuticals, Inc. G-protein coupled heptahelical receptor binding compounds and methods of use thereof
CO5160290A1 (es) 1999-03-29 2002-05-30 Novartis Ag Derivados de acido fenoxifeniloxamico sustituido .
US6159694A (en) * 1999-04-08 2000-12-12 Isis Pharmaceuticals Inc. Antisense modulation of stat3 expression
CA2377771A1 (fr) 1999-07-01 2001-01-11 Ajinomoto Co., Inc. Composes heterocycliques et leurs applications en medecine
JP2001089412A (ja) 1999-09-22 2001-04-03 Otsuka Pharmaceut Co Ltd ベンゼン誘導体またはその医薬的に許容される塩
JP2001089450A (ja) 1999-09-22 2001-04-03 Otsuka Pharmaceut Co Ltd ピリジン誘導体含有医薬製剤
WO2001060354A1 (fr) * 2000-02-15 2001-08-23 Teijin Limited Medicament anticancereux comprenant un derive d'acide anthranilique en tant qu'ingredient actif
MXPA02011400A (es) 2000-05-22 2003-05-23 Aventis Pharm Prod Inc Derivados de arimetilamina para uso como inhibidores de triptasa.
GB0015205D0 (en) 2000-06-21 2000-08-09 Karobio Ab Bioisosteric thyroid receptor ligands and method
US6479510B2 (en) 2000-08-18 2002-11-12 Pharmacia & Upjohn Company Quinuclidine-substituted aryl compounds for treatment of disease
EP1379127B1 (fr) 2000-09-28 2013-04-17 Nanocyte Inc. Procedes, compositions et dispositifs utilisant des cellules/capsules urticantes pour administrer un agent therapeutique ou cosmetique dans un tissu
WO2002032408A2 (fr) 2000-10-20 2002-04-25 Novartis Ag Compositions
EP1211235A3 (fr) 2000-11-30 2004-01-02 JFE Chemical Corporation Procédé de préparation d'éthers d'acide diphényldicarboxylique et ses dérivés
JP2004269356A (ja) 2000-12-27 2004-09-30 Ajinomoto Co Inc 創傷部癒着防止剤
GB2374009A (en) 2001-02-12 2002-10-09 Novartis Ag Method of treating hair loss
EA006447B1 (ru) 2001-06-20 2005-12-29 Пфайзер Продактс Инк. Новые производные сульфоновых кислот
MXPA04000779A (es) 2001-08-24 2004-04-20 Pharmacia & Up John Company 7-aza[2.2.1]bicicloheptanos sustituidos con arilo para el tratamiento de enfermedades.
BR0213452A (pt) 2001-10-22 2004-11-09 Pfizer Prod Inc Derivados de piperazina com atividade antagonista receptora de ccr1
WO2003035602A1 (fr) 2001-10-25 2003-05-01 Sankyo Company, Limited Modulateurs lipidiques
CA2476417A1 (fr) 2002-02-15 2003-08-28 Pharmacia & Upjohn Company Composes aryle substitues permettant de traiter une maladie
FR2836917B1 (fr) 2002-03-11 2006-02-24 Lipha Derives nitroso de la diphenylamine, compositions pharmaceutiques les contenant en tant que medicaments utilisables dans le traitement des pathologies caracterisees par une situation de stress oxydatif
JP2004035475A (ja) 2002-07-03 2004-02-05 Ajinomoto Co Inc ＴＧＦβ作用抑制剤
TW201018661A (en) 2003-03-14 2010-05-16 Ono Pharmaceutical Co Heterocyclic rinf having nitrogen atom derivatives and medicament containing the derivatives as active ingredient
WO2005007621A2 (fr) * 2003-05-30 2005-01-27 Rigel Pharmaceuticals, Inc. Inhibiteurs de ligase d'ubiquitine
ATE469878T1 (de) * 2003-07-24 2010-06-15 Leo Pharma As Aminobenzophenonverbindungen
KR100927563B1 (ko) * 2004-08-06 2009-11-23 오쓰까 세이야꾸 가부시키가이샤 방향족 화합물
UA95978C2 (ru) * 2006-10-02 2011-09-26 Оцука Фармас'Ютікел Ко., Лтд. Ингибитор активации stat3/5
TWI440638B (zh) * 2007-10-30 2014-06-11 Otsuka Pharma Co Ltd 雜環化合物及其藥學組成物

Also Published As

Publication number Publication date
TW200800200A (en) 2008-01-01
EP1957073B1 (fr) 2014-04-23
EP1957073A2 (fr) 2008-08-20
RU2008127325A (ru) 2010-01-20
BRPI0619349A2 (pt) 2011-11-08
ES2463450T3 (es) 2014-05-28
WO2007066784A3 (fr) 2007-10-25
US8236826B2 (en) 2012-08-07
TWI332838B (en) 2010-11-11
PL1957073T3 (pl) 2014-09-30
DK1957073T3 (da) 2014-05-12
AU2006323700A1 (en) 2007-06-14
CN101321529A (zh) 2008-12-10
CN101321529B (zh) 2012-09-05
CA2630468C (fr) 2015-01-20
PT1957073E (pt) 2014-05-12
SI1957073T1 (sl) 2014-08-29
WO2007066784A2 (fr) 2007-06-14
CY1115171T1 (el) 2016-12-14
KR20080070054A (ko) 2008-07-29
US20100004438A1 (en) 2010-01-07
AR056885A1 (es) 2007-10-31
KR101157004B1 (ko) 2012-07-09
HK1123219A1 (en) 2009-06-12
MY146514A (en) 2012-08-15
RU2444362C2 (ru) 2012-03-10
ZA200804445B (en) 2009-11-25
IL191544A0 (en) 2008-12-29
CA2630468A1 (fr) 2007-06-14
AU2006323700B2 (en) 2011-02-17

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