NO323296B1 - Stabil vandig formulering av en peptidbeslektet forbindelse, fremgangsmate for fremstilling av denne og anvendelse derav for fremstillingen av medikamenter. - Google Patents
Stabil vandig formulering av en peptidbeslektet forbindelse, fremgangsmate for fremstilling av denne og anvendelse derav for fremstillingen av medikamenter. Download PDFInfo
- Publication number
- NO323296B1 NO323296B1 NO19986208A NO986208A NO323296B1 NO 323296 B1 NO323296 B1 NO 323296B1 NO 19986208 A NO19986208 A NO 19986208A NO 986208 A NO986208 A NO 986208A NO 323296 B1 NO323296 B1 NO 323296B1
- Authority
- NO
- Norway
- Prior art keywords
- peptide
- leuprolide
- lhrh
- formulation according
- stable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2119996P | 1996-07-03 | 1996-07-03 | |
| PCT/US1997/010816 WO1998000157A1 (fr) | 1996-07-03 | 1997-07-01 | Preparations aqueuses de peptides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO986208D0 NO986208D0 (no) | 1998-12-30 |
| NO986208L NO986208L (no) | 1998-12-30 |
| NO323296B1 true NO323296B1 (no) | 2007-03-05 |
Family
ID=21802912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19986208A NO323296B1 (no) | 1996-07-03 | 1998-12-30 | Stabil vandig formulering av en peptidbeslektet forbindelse, fremgangsmate for fremstilling av denne og anvendelse derav for fremstillingen av medikamenter. |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US5916582A (fr) |
| EP (1) | EP0909177B1 (fr) |
| JP (2) | JP2001504442A (fr) |
| CN (1) | CN1256146C (fr) |
| AR (1) | AR007715A1 (fr) |
| AT (1) | ATE259241T1 (fr) |
| AU (1) | AU3574897A (fr) |
| BR (1) | BR9710131A (fr) |
| CA (1) | CA2259505A1 (fr) |
| CO (1) | CO4890855A1 (fr) |
| CZ (1) | CZ298464B6 (fr) |
| DE (1) | DE69727572T2 (fr) |
| ES (1) | ES2213828T3 (fr) |
| HU (1) | HU225691B1 (fr) |
| ID (1) | ID19305A (fr) |
| IL (1) | IL127770A (fr) |
| MY (1) | MY125556A (fr) |
| NO (1) | NO323296B1 (fr) |
| NZ (1) | NZ333579A (fr) |
| PL (1) | PL189403B1 (fr) |
| RO (1) | RO120611B1 (fr) |
| RU (1) | RU2201248C2 (fr) |
| SK (1) | SK284283B6 (fr) |
| TW (1) | TW586932B (fr) |
| WO (1) | WO1998000157A1 (fr) |
| ZA (1) | ZA975943B (fr) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020173748A1 (en) | 1998-10-29 | 2002-11-21 | Mcconnell Susan | Reservoir connector |
| US6800071B1 (en) | 1998-10-29 | 2004-10-05 | Medtronic Minimed, Inc. | Fluid reservoir piston |
| JP3546015B2 (ja) | 1998-10-29 | 2004-07-21 | メドトロニック ミニメド インコーポレイテッド | 小型で経済的なポンプ駆動システム |
| US7193521B2 (en) | 1998-10-29 | 2007-03-20 | Medtronic Minimed, Inc. | Method and apparatus for detecting errors, fluid pressure, and occlusions in an ambulatory infusion pump |
| US6248093B1 (en) | 1998-10-29 | 2001-06-19 | Minimed Inc. | Compact pump drive system |
| US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
| US20070148228A1 (en) * | 1999-02-22 | 2007-06-28 | Merrion Research I Limited | Solid oral dosage form containing an enhancer |
| US8119159B2 (en) * | 1999-02-22 | 2012-02-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
| US7658938B2 (en) * | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
| US7063684B2 (en) | 1999-10-28 | 2006-06-20 | Medtronic Minimed, Inc. | Drive system seal |
| US7884071B2 (en) * | 2002-09-27 | 2011-02-08 | Zentaris Gmbh | Administration form for pharmaceutically active peptides with sustained release and method for the production thereof |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US6984403B2 (en) * | 2003-12-04 | 2006-01-10 | Pfizer Inc. | Azithromycin dosage forms with reduced side effects |
| US20060039949A1 (en) * | 2004-08-20 | 2006-02-23 | Nycz Jeffrey H | Acetabular cup with controlled release of an osteoinductive formulation |
| US20060045902A1 (en) * | 2004-09-01 | 2006-03-02 | Serbousek Jon C | Polymeric wrap for in vivo delivery of osteoinductive formulations |
| US20060057184A1 (en) * | 2004-09-16 | 2006-03-16 | Nycz Jeffrey H | Process to treat avascular necrosis (AVN) with osteoinductive materials |
| CN101106979A (zh) * | 2005-01-21 | 2008-01-16 | 阿尔扎公司 | 具有改善的稳定性的含有至少一种反离子的用于涂覆微针的治疗性的肽试剂 |
| US8137664B2 (en) * | 2005-02-02 | 2012-03-20 | Sdgi Holdings, Inc. | Method and kit for repairing a defect in bone |
| WO2006083761A2 (fr) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solutions de solvant/polymere utilisees comme vehicules de suspension |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| CA2602249C (fr) * | 2005-04-08 | 2012-07-10 | Amylin Pharmaceuticals, Inc. | Formulations de peptides et de proteines ayant une meilleure stabilite |
| CN100336557C (zh) * | 2005-05-11 | 2007-09-12 | 北京双鹭药业股份有限公司 | 一种生长抑素的水溶液制剂、其制备方法及应用 |
| US20060293243A1 (en) * | 2005-06-17 | 2006-12-28 | Navneet Puri | Stable, buffered, pharmaceutical compositions including motilin-like peptides |
| US20060287243A1 (en) * | 2005-06-17 | 2006-12-21 | Navneet Puri | Stable pharmaceutical compositions including motilin-like peptides |
| ES2426445T3 (es) * | 2006-04-07 | 2013-10-23 | Merrion Research Iii Limited | Forma de dosificación oral sólida que contiene un potenciador |
| ATE481963T1 (de) | 2006-05-30 | 2010-10-15 | Intarcia Therapeutics Inc | Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem |
| US7682356B2 (en) | 2006-08-09 | 2010-03-23 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies for use therein |
| CA2683610C (fr) | 2007-04-23 | 2013-01-08 | Intarcia Therapeutics, Inc. | Formulations en suspension de peptides insulinotropes et leurs utilisations |
| WO2009002874A1 (fr) | 2007-06-22 | 2008-12-31 | Board Of Regents, The University Of Texas System | Formation de particules de peptide ou de protéine submicroniques stables par congélation de film mince |
| RU2010113968A (ru) * | 2007-09-11 | 2011-10-20 | Мондобайотек Лабораториз Аг (Li) | Применение пептида в качестве терапевтического средства |
| WO2009102467A2 (fr) | 2008-02-13 | 2009-08-20 | Intarcia Therapeutics, Inc. | Dispositifs, formulations et méthodes d’administration de plusieurs agents bénéfiques |
| BRPI0912384A2 (pt) * | 2008-05-07 | 2015-10-13 | Merrion Res Iii Ltd | composição, e, método para preparar uma composição |
| NZ591713A (en) | 2008-08-15 | 2013-07-26 | Ironwood Pharmaceuticals Inc | Solid stable formulations of linaclotide for oral administration |
| JP5711138B2 (ja) | 2008-11-16 | 2015-04-30 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 高濃度の低粘度懸濁液 |
| JP2012518686A (ja) * | 2009-02-25 | 2012-08-16 | メリオン・リサーチ・Iii・リミテッド | ビスホスホネート類の組成物および薬物送達 |
| EP2246063A1 (fr) * | 2009-04-29 | 2010-11-03 | Ipsen Pharma S.A.S. | Formulations à libération prolongée contenant des analogues de GnRH |
| CA2770077A1 (fr) | 2009-08-06 | 2011-02-10 | Ironwood Pharmaceuticals, Inc. | Formulations comprenant du linaclotide |
| ES2650667T3 (es) | 2009-09-28 | 2018-01-19 | Intarcia Therapeutics, Inc | Rápido establecimiento y/o terminación de la administración sustancial de fármaco en estado estacionario |
| US20110182985A1 (en) * | 2010-01-28 | 2011-07-28 | Coughlan David C | Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof |
| CA2790213A1 (fr) | 2010-02-17 | 2011-08-25 | Ironwood Pharmaceuticals, Inc. | Traitements de troubles gastro-intestinaux |
| WO2011120033A1 (fr) * | 2010-03-26 | 2011-09-29 | Merrion Research Iii Limited | Compositions pharmaceutiques d'inhibiteurs de facteur xa sélectifs destinées à une administration orale |
| PT2603232T (pt) | 2010-08-11 | 2020-01-09 | Ironwood Pharmaceuticals Inc | Formulações estáveis de linaclotida |
| US8802114B2 (en) | 2011-01-07 | 2014-08-12 | Merrion Research Iii Limited | Pharmaceutical compositions of iron for oral administration |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| ES2614864T3 (es) | 2011-08-17 | 2017-06-02 | Ironwood Pharmaceuticals, Inc. | Tratamientos para trastornos gastrointestinales |
| US10112987B2 (en) | 2012-01-09 | 2018-10-30 | Icb International, Inc. | Blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an amyloid-beta peptide |
| US20140271923A1 (en) | 2013-03-14 | 2014-09-18 | Christopher Brian Reid | Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions |
| EP2832361A1 (fr) * | 2013-07-29 | 2015-02-04 | Ipsen Pharma S.A.S. | Compositions à libération prolongée aqueuse d'analogues de LHRH |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| US10265384B2 (en) | 2015-01-29 | 2019-04-23 | Novo Nordisk A/S | Tablets comprising GLP-1 agonist and enteric coating |
| ES2968262T3 (es) | 2015-06-03 | 2024-05-08 | I2O Therapeutics Inc | Sistemas de colocación de implantes |
| CN105749245A (zh) * | 2016-03-02 | 2016-07-13 | 张光泉 | 抗癌药醋酸地加瑞克注射液及其制备方法 |
| EP3458084B1 (fr) | 2016-05-16 | 2020-04-01 | Intarcia Therapeutics, Inc | Polypeptides sélectifs pour le récepteur du glucagon et méthodes pour leur utilisation |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| MX2019008006A (es) | 2017-01-03 | 2019-08-29 | Intarcia Therapeutics Inc | Metodos que comprenden la administracion continua de un agonista del receptor de glp-1 y la co-administracion de un farmaco. |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3914412A (en) * | 1973-10-11 | 1975-10-21 | Abbott Lab | {8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity |
| US4234571A (en) * | 1979-06-11 | 1980-11-18 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone |
| US4248864A (en) * | 1979-08-30 | 1981-02-03 | American Home Products Corporation | Reproduction control |
| EP0111841B1 (fr) * | 1982-12-10 | 1987-05-06 | Syntex (U.S.A.) Inc. | Préparations de LHRH pour l'administration nasale |
| US4547370A (en) * | 1983-11-29 | 1985-10-15 | The Salk Institute For Biological Studies | GnRH Antagonists |
| US4661472A (en) * | 1985-05-09 | 1987-04-28 | The Salk Institute For Biological Studies | GnRH antagonists IX |
| US4851385A (en) * | 1987-07-15 | 1989-07-25 | Indiana University Foundation | LHRH antagonist analogs having low histamine-release activity |
| US4800191A (en) * | 1987-07-17 | 1989-01-24 | Schally Andrew Victor | LHRH antagonists |
| DD273980B5 (de) * | 1988-07-12 | 1994-04-14 | Berlin Chemie Ag | Verfahren zur Herstellung von Insulin-Pr{paraten zur rektalen Anwendung |
| US5034229A (en) * | 1988-12-13 | 1991-07-23 | Alza Corporation | Dispenser for increasing feed conversion of hog |
| US5057318A (en) * | 1988-12-13 | 1991-10-15 | Alza Corporation | Delivery system for beneficial agent over a broad range of rates |
| US5110596A (en) * | 1988-12-13 | 1992-05-05 | Alza Corporation | Delivery system comprising means for delivering agent to livestock |
| US4980163A (en) * | 1989-03-01 | 1990-12-25 | Public Health Research Institute Of The City Of New York | Novel bacteriocin compositions for use as enhanced broad range bactericides and methods of preventing and treating microbial infection |
| SU1680198A1 (ru) * | 1990-08-09 | 1991-09-30 | Центральный институт усовершенствования врачей | Способ лечени реактивных артритов |
| DE4117507A1 (de) * | 1991-05-24 | 1992-11-26 | Schering Ag | Verfahren zur herstellung von n(pfeil hoch)6(pfeil hoch)-substituierten lysin-derivaten |
| US5446025A (en) * | 1992-06-12 | 1995-08-29 | Abbott Laboratories | Formulations and method of the percutaneous administration of leuprolide |
| TW333456B (en) * | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
| NZ262634A (en) * | 1993-02-23 | 1997-02-24 | Genentech Inc | Stabilizing polypeptides against degradation by organic solvents by admixing the peptide with trehalose or mannitol |
| DE4320201A1 (de) * | 1993-06-18 | 1995-01-12 | Asta Medica Ag | Verwendung von Cetrorelix und weiteren Nona- und Dekapeptiden zur Herstellung eines Arzneimittels zur Bekämpfung von Aids und zur Wachstumsstimulation |
| US5482931A (en) * | 1993-06-29 | 1996-01-09 | Ferring Ab | Stabilized pharmaceutical peptide compositions |
| DE69427820T2 (de) * | 1993-06-29 | 2001-11-08 | Ferring B.V., Hoofdorp | Zusammensetzungen zur nasalen verabreichung von desmopressin |
| US5413990A (en) * | 1993-08-06 | 1995-05-09 | Tap Pharmaceuticals Inc. | N-terminus modified analogs of LHRH |
| US5595760A (en) * | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
| RO119929B1 (ro) * | 1996-02-02 | 2005-06-30 | Alza Corporation | Dispozitiv pentru administrarea unui agent activ, într-un mediu lichid |
-
1997
- 1997-06-13 US US08/874,694 patent/US5916582A/en not_active Expired - Lifetime
- 1997-06-28 MY MYPI97002941A patent/MY125556A/en unknown
- 1997-07-01 AU AU35748/97A patent/AU3574897A/en not_active Abandoned
- 1997-07-01 SK SK1798-98A patent/SK284283B6/sk not_active IP Right Cessation
- 1997-07-01 CA CA002259505A patent/CA2259505A1/fr not_active Abandoned
- 1997-07-01 WO PCT/US1997/010816 patent/WO1998000157A1/fr active IP Right Grant
- 1997-07-01 RU RU99102246/14A patent/RU2201248C2/ru not_active IP Right Cessation
- 1997-07-01 CN CNB971960526A patent/CN1256146C/zh not_active Expired - Fee Related
- 1997-07-01 AT AT97932237T patent/ATE259241T1/de not_active IP Right Cessation
- 1997-07-01 IL IL127770A patent/IL127770A/en not_active IP Right Cessation
- 1997-07-01 RO RO98-01770A patent/RO120611B1/ro unknown
- 1997-07-01 CZ CZ0433998A patent/CZ298464B6/cs not_active IP Right Cessation
- 1997-07-01 EP EP97932237A patent/EP0909177B1/fr not_active Expired - Lifetime
- 1997-07-01 ES ES97932237T patent/ES2213828T3/es not_active Expired - Lifetime
- 1997-07-01 NZ NZ333579A patent/NZ333579A/en not_active IP Right Cessation
- 1997-07-01 PL PL97330903A patent/PL189403B1/pl not_active IP Right Cessation
- 1997-07-01 DE DE69727572T patent/DE69727572T2/de not_active Expired - Lifetime
- 1997-07-01 JP JP50421998A patent/JP2001504442A/ja not_active Ceased
- 1997-07-01 BR BR9710131A patent/BR9710131A/pt not_active Application Discontinuation
- 1997-07-01 HU HU0000589A patent/HU225691B1/hu not_active IP Right Cessation
- 1997-07-02 AR ARP970102966A patent/AR007715A1/es unknown
- 1997-07-03 ZA ZA9705943A patent/ZA975943B/xx unknown
- 1997-07-03 CO CO97037100A patent/CO4890855A1/es unknown
- 1997-07-03 ID IDP972313A patent/ID19305A/id unknown
- 1997-08-22 TW TW086109391A patent/TW586932B/zh active
-
1998
- 1998-12-30 NO NO19986208A patent/NO323296B1/no not_active IP Right Cessation
-
1999
- 1999-02-11 US US09/248,286 patent/US6068850A/en not_active Expired - Lifetime
-
2008
- 2008-06-25 JP JP2008165927A patent/JP2008291037A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO323296B1 (no) | Stabil vandig formulering av en peptidbeslektet forbindelse, fremgangsmate for fremstilling av denne og anvendelse derav for fremstillingen av medikamenter. | |
| EP0909175B1 (fr) | Formulations protiques non aqueuses de peptides | |
| NO322514B1 (no) | Stabile, ikke-vandige formuleringer av en LHRH-beslektet peptidforbindelse og fremgangsmater for fremstilling av disse. | |
| US5981489A (en) | Non-aqueous protic peptide formulations | |
| AU2004242540B2 (en) | Aqueous formulations of peptides | |
| KR100594519B1 (ko) | 비수성양성자성펩티드제제 | |
| KR100517091B1 (ko) | 펩티드의수성제제 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |