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NO954762L - Nye tiazolindindioner og legemiddel inneholdende slike - Google Patents

Nye tiazolindindioner og legemiddel inneholdende slike

Info

Publication number
NO954762L
NO954762L NO954762A NO954762A NO954762L NO 954762 L NO954762 L NO 954762L NO 954762 A NO954762 A NO 954762A NO 954762 A NO954762 A NO 954762A NO 954762 L NO954762 L NO 954762L
Authority
NO
Norway
Prior art keywords
denotes
pct
alkyl
heteroatoms
sec
Prior art date
Application number
NO954762A
Other languages
English (en)
Other versions
NO307832B1 (no
NO954762D0 (no
Inventor
Alfred Mertens
Hans-Peter Wolff
Peter Freund
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of NO954762D0 publication Critical patent/NO954762D0/no
Publication of NO954762L publication Critical patent/NO954762L/no
Publication of NO307832B1 publication Critical patent/NO307832B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO954762A 1993-05-25 1995-11-24 Nye tiazolidindioner og legemiddel inneholdende slike NO307832B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4317320A DE4317320A1 (de) 1993-05-25 1993-05-25 Neue Thiazolidindione und diese enthaltende Arzneimittel
PCT/EP1994/001619 WO1994027995A1 (de) 1993-05-25 1994-05-19 Neue thiazolidindione und diese enthaltende arzneimittel

Publications (3)

Publication Number Publication Date
NO954762D0 NO954762D0 (no) 1995-11-24
NO954762L true NO954762L (no) 1995-11-24
NO307832B1 NO307832B1 (no) 2000-06-05

Family

ID=6488833

Family Applications (1)

Application Number Title Priority Date Filing Date
NO954762A NO307832B1 (no) 1993-05-25 1995-11-24 Nye tiazolidindioner og legemiddel inneholdende slike

Country Status (25)

Country Link
US (1) US5599826A (no)
EP (1) EP0700397B1 (no)
JP (1) JP3162721B2 (no)
KR (1) KR100243783B1 (no)
CN (1) CN1040324C (no)
AT (1) ATE223409T1 (no)
AU (1) AU682699B2 (no)
CA (1) CA2163028C (no)
CL (1) CL2004001167A1 (no)
CY (1) CY2415B1 (no)
CZ (1) CZ285927B6 (no)
DE (2) DE4317320A1 (no)
DK (1) DK0700397T3 (no)
ES (1) ES2180581T3 (no)
FI (1) FI955685L (no)
HU (1) HU217065B (no)
NO (1) NO307832B1 (no)
NZ (1) NZ267410A (no)
PL (1) PL180046B1 (no)
PT (1) PT700397E (no)
RO (1) RO114328B1 (no)
RU (1) RU2122002C1 (no)
SK (1) SK282618B6 (no)
UA (1) UA41362C2 (no)
WO (1) WO1994027995A1 (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07138258A (ja) * 1993-11-16 1995-05-30 Taiho Yakuhin Kogyo Kk チアゾリジンジオン誘導体又はその塩
DE69627164T2 (de) * 1995-07-31 2004-01-29 Shionogi & Co Pyrrolydin-derivate mit einer phospholipase a2 inhibierenden wirkung
JPH09176162A (ja) * 1995-12-22 1997-07-08 Toubishi Yakuhin Kogyo Kk チアゾリジンジオン誘導体及びその製造法並びにそれを含む医薬組成物
DE19619819A1 (de) * 1996-05-16 1997-11-20 Boehringer Mannheim Gmbh Neue Thiazolidindione, Verfahren zu ihrer Herstellung und diese enthaltenden Arzneimittel
DE19711617A1 (de) * 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Neue Thiazolidindione, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE19711616A1 (de) * 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
US6028088A (en) * 1998-10-30 2000-02-22 The University Of Mississippi Flavonoid derivatives
GB9824893D0 (en) * 1998-11-12 1999-01-06 Smithkline Beckman Corp Novel method of treatment
CA2350599A1 (en) * 1998-11-20 2000-06-02 Genentech, Inc. Method of inhibiting angiogenesis
PT1078923E (pt) 1999-08-02 2006-07-31 Hoffmann La Roche Processo para a preparacao de derivados de benzotiofeno
US6531609B2 (en) 2000-04-14 2003-03-11 Hoffmann-La Roche Inc. Process for the preparation of thiazolidinedione derivatives
EP1283830B1 (en) * 2000-05-08 2008-06-18 F. Hoffmann-La Roche Ag Para-amine substituted phenylamide glucokinase activators
ATE334662T1 (de) 2000-06-27 2006-08-15 Hoffmann La Roche Herstellungsverfahren von arzneizubereitungen
CZ20031772A3 (cs) * 2000-12-25 2003-11-12 Ono Pharmaceutical Co., Ltd. Derivát dihydronaftalenu a činidlo obsahující tento derivát jako účinnou složku
JP2004525168A (ja) 2001-04-06 2004-08-19 エフ．ホフマン−ラ　ロシュ　アーゲー 腫瘍の成長を抑制もしくは減少するための単独または他の治療薬との組合わせでのチアゾリジンジオン
MXPA03010435A (es) * 2001-05-15 2004-03-09 Hoffmann La Roche Derivados de oxazol acido carboxilico sustituidos para uso como activadores de proliferacion del peroximosa(ppar-alfa y gama) en el tratamiento de diabetes.
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd ５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法
US7102000B2 (en) * 2002-03-08 2006-09-05 Incyte San Diego Inc. Heterocyclic amide derivatives for the treatment of diabetes and other diseases
WO2004005266A1 (en) * 2002-07-03 2004-01-15 F. Hoffmann-La Roche Ag Oxazole derivatives and their use as insulin sensitizers
EP1537091B1 (en) * 2002-08-30 2010-10-06 F. Hoffmann-La Roche AG Novel 2-arylthiazole compounds as pparalpha and ppargamma agonists
PT1539746E (pt) * 2002-09-12 2007-02-28 Hoffmann La Roche Compostos de ácido 1h-indol-5-propiónico, substituído em n, como agonistas de ppar (receptores activados dos proliferadores de peroxissoma), úteis para o tratamento de diabetes
ATE405560T1 (de) * 2002-11-25 2008-09-15 Hoffmann La Roche Indolderivaten
JP2007506671A (ja) 2003-06-26 2007-03-22 エフ．ホフマン−ラ　ロシュ　アーゲー インスリン抵抗性改善薬を製造する方法およびその中間体化合物
CN101693202B (zh) * 2009-10-21 2011-04-20 沧州那瑞化学科技有限公司 盐酸吡咯列酮关键中间体加氢反应催化剂及加氢反应方法
US20150004144A1 (en) 2011-12-02 2015-01-01 The General Hospital Corporation Differentiation into brown adipocytes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1003445B (zh) * 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
HU210339B (en) * 1985-05-21 1995-03-28 Pfizer Process for preparing thiazolidinediones and their pharmaceutical compositions haring hypoglycemic effect
GB8713861D0 (en) * 1987-06-13 1987-07-15 Beecham Group Plc Compounds
US4912909A (en) * 1988-03-04 1990-04-03 Kurt H. Volk, Inc. Direct mail article with mailable reply card
WO1989008652A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Thiazolidinedione derivatives as hypoglycemic agents
HUT65619A (en) * 1990-07-03 1994-07-28 Yamanouchi Pharma Co Ltd Process for producing bisheterocyclic compounds and pharmaceutical preparations containing them
FR2688220A1 (fr) * 1992-03-06 1993-09-10 Adir Nouveaux derives de thiazolidine-2,4-dione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
CA2163028C (en) 2003-11-25
ATE223409T1 (de) 2002-09-15
AU6970494A (en) 1994-12-20
CA2163028A1 (en) 1994-12-08
HU217065B (hu) 1999-11-29
WO1994027995A1 (de) 1994-12-08
NO307832B1 (no) 2000-06-05
JP3162721B2 (ja) 2001-05-08
CZ299995A3 (en) 1996-03-13
KR960702460A (ko) 1996-04-27
NO954762D0 (no) 1995-11-24
RU2122002C1 (ru) 1998-11-20
SK146195A3 (en) 1996-06-05
AU682699B2 (en) 1997-10-16
SK282618B6 (sk) 2002-10-08
PL180046B1 (en) 2000-12-29
CZ285927B6 (cs) 1999-11-17
PL311752A1 (en) 1996-03-18
CL2004001167A1 (es) 2005-05-20
FI955685A7 (fi) 1995-11-24
PT700397E (pt) 2002-12-31
CY2415B1 (en) 2004-11-12
CN1040324C (zh) 1998-10-21
HUT75099A (en) 1997-04-28
DK0700397T3 (da) 2003-01-06
RO114328B1 (ro) 1999-03-30
EP0700397B1 (de) 2002-09-04
DE4317320A1 (de) 1994-12-01
KR100243783B1 (ko) 2000-03-02
CN1124488A (zh) 1996-06-12
DE59410181D1 (de) 2002-10-10
JPH08510456A (ja) 1996-11-05
FI955685A0 (fi) 1995-11-24
EP0700397A1 (de) 1996-03-13
ES2180581T3 (es) 2003-02-16
US5599826A (en) 1997-02-04
UA41362C2 (uk) 2001-09-17
FI955685L (fi) 1995-11-24
HU9503376D0 (en) 1996-01-29
NZ267410A (en) 1996-12-20

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