NO990544L - Substituerte pyrido- eller pyrimido-inneholdende 6,6 eller 6,7-bycykliske derivater - Google Patents

Substituerte pyrido- eller pyrimido-inneholdende 6,6 eller 6,7-bycykliske derivater

Info

Publication number: NO990544L
Authority: NO; Norway
Prior art keywords: pyrimido; cyclic derivatives; substituted pyrido; pyrido; substituted
Prior art date: 1996-08-06

Application number

NO990544A

Other languages

English (en)

Other versions

NO990544D0 (no

NO313293B1 (no

Inventor

Yuhpyng Liang Chen

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-06

Filing date

1999-02-05

Publication date

1999-03-31

1999-02-05 Application filed by Pfizer filed Critical Pfizer

1999-02-05 Publication of NO990544D0 publication Critical patent/NO990544D0/no

1999-03-31 Publication of NO990544L publication Critical patent/NO990544L/no

2002-09-09 Publication of NO313293B1 publication Critical patent/NO313293B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Oncology (AREA)
Virology (AREA)
Obesity (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Other In-Based Heterocyclic Compounds (AREA)

NO19990544A 1996-08-06 1999-02-05 Substituerte pyrido- eller pyrimido-holdige 6,6- eller 6,7- bicykliske derivater, anvendelse derav og farmasöytisk preparat NO313293B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US2345396P	1996-08-06	1996-08-06
PCT/IB1997/000918 WO1998005661A1 (en)	1996-08-06	1997-07-23	Substituted pyrido- or pyrimido-containing 6,6- or 6,7-bicyclic derivatives

Publications (3)

Publication Number	Publication Date
NO990544D0 NO990544D0 (no)	1999-02-05
NO990544L true NO990544L (no)	1999-03-31
NO313293B1 NO313293B1 (no)	2002-09-09

Family

ID=21815208

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19990544A NO313293B1 (no)	1996-08-06	1999-02-05	Substituerte pyrido- eller pyrimido-holdige 6,6- eller 6,7- bicykliske derivater, anvendelse derav og farmasöytisk preparat

Country Status (40)

Country	Link
US (1)	US6492520B1 (no)
EP (1)	EP0920429B1 (no)
JP (1)	JP3345021B2 (no)
KR (1)	KR20000029843A (no)
CN (1)	CN1093130C (no)
AP (1)	AP1096A (no)
AR (1)	AR008829A1 (no)
AT (1)	ATE232863T1 (no)
AU (1)	AU709203B2 (no)
BG (1)	BG103143A (no)
BR (1)	BR9710808A (no)
CA (1)	CA2262692C (no)
CO (1)	CO4900060A1 (no)
CZ (1)	CZ292806B6 (no)
DE (1)	DE69719193T2 (no)
DK (1)	DK0920429T3 (no)
DZ (1)	DZ2289A1 (no)
EA (1)	EA003188B1 (no)
ES (1)	ES2191183T3 (no)
GT (1)	GT199700089A (no)
HR (1)	HRP970432B1 (no)
ID (1)	ID17980A (no)
IL (1)	IL128188A0 (no)
IS (1)	IS4948A (no)
MA (1)	MA24296A1 (no)
NO (1)	NO313293B1 (no)
NZ (1)	NZ333727A (no)
OA (1)	OA10970A (no)
PA (1)	PA8435201A1 (no)
PE (1)	PE97098A1 (no)
PL (1)	PL331602A1 (no)
SA (1)	SA97180334A (no)
SK (1)	SK14099A3 (no)
TN (1)	TNSN97135A1 (no)
TR (1)	TR199900228T2 (no)
TW (1)	TW550265B (no)
UY (1)	UY24655A1 (no)
WO (1)	WO1998005661A1 (no)
YU (1)	YU5399A (no)
ZA (1)	ZA976954B (no)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6187777B1 (en)	1998-02-06	2001-02-13	Amgen Inc.	Compounds and methods which modulate feeding behavior and related diseases
ATE266399T1 (de)	1998-08-20	2004-05-15	Smithkline Beecham Corp	Neue substituierte triazolverbindungen
CN1178941C (zh)	1998-11-12	2004-12-08	纽罗克里恩生物科学有限公司	Crf受体拮抗剂以及与其有关的方法
NZ510955A (en)	1998-11-12	2003-01-31	Neurocrine Biosciences Inc	Tricyclic nitrogen containing ring system useful as CRF receptor antagonists
US6432989B1 (en)	1999-08-27	2002-08-13	Pfizer Inc	Use of CRF antagonists to treat circadian rhythm disorders
IL139197A0 (en) *	1999-10-29	2001-11-25	Pfizer Prod Inc	Use of corticotropin releasing factor antagonists and related compositions
AU2001232271A1 (en) *	2000-02-14	2001-08-20	Japan Tobacco Inc.	Preventives/remedies for postoperative stress
AU2001234180A1 (en) *	2000-02-25	2001-09-03	Japan Tobacco Inc.	Benzamide derivative and use thereof
AR030053A1 (es) *	2000-03-02	2003-08-13	Smithkline Beecham Corp	1h-pirimido [4,5-d] pirimidin-2-onas y sales, composiciones farmaceuticas, uso para la fabricacion de un medicamento y procedimiento para producirlas
US7235551B2 (en) *	2000-03-02	2007-06-26	Smithkline Beecham Corporation	1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
GB0011964D0 (en)	2000-05-18	2000-07-05	Suyal N	Thick glass films with controlled refractive indices and their applications
NZ524806A (en)	2000-10-23	2006-03-31	Smithkline Beecham Corp	Tri-substituted 8H-pyrido[2,3-d]pyrimidin-7-one compounds
GB0117396D0 (en)	2001-07-17	2001-09-05	Glaxo Group Ltd	Chemical compounds
BR0212864A (pt)	2001-09-26	2004-08-17	Bayer Pharmaceuticals Corp	Derivados de 1,6-naftiridina como antidiabéticos
EP1499320B1 (en)	2002-04-19	2007-08-22	Smithkline Beecham Corporation	Novel compounds
FR2846657B1 (fr)	2002-11-05	2004-12-24	Servier Lab	Nouveaux composes pyridopyrimidinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ES2338545T3 (es)	2002-12-20	2010-05-10	Pfizer Products Inc.	Derivados de pirimidina para el tratamiento del crecimiento celular anormal.
US7109337B2 (en)	2002-12-20	2006-09-19	Pfizer Inc	Pyrimidine derivatives for the treatment of abnormal cell growth
GB0308208D0 (en) *	2003-04-09	2003-05-14	Glaxo Group Ltd	Chemical compounds
US8309562B2 (en)	2003-07-03	2012-11-13	Myrexis, Inc.	Compounds and therapeutical use thereof
AU2004253967B2 (en)	2003-07-03	2010-02-18	Cytovia, Inc.	4-arylamino-quinazolines as activators of caspases and inducers of apoptosis
WO2006074147A2 (en)	2005-01-03	2006-07-13	Myriad Genetics, Inc.	Nitrogen containing bicyclic compounds and therapeutical use thereof
US20050085479A1 (en) *	2003-08-27	2005-04-21	Pharmacia Corporation	Mediated central nervous system compositions of a cyclooxygenase-2 selective inhibitor and a corticotropin releasing factor antagonist for the treatment of ischemic disorders or injury
WO2005099688A2 (en) *	2004-04-07	2005-10-27	Takeda Pharmaceutical Company Limited	Cyclic compounds
BRPI0510980A (pt)	2004-05-14	2007-11-27	Pfizer Prod Inc	derivados de pirimidina para o tratamento do crescimento anormal de células
CA2564199A1 (en)	2004-05-14	2005-11-24	Pfizer Products Inc.	Pyrimidine derivatives for the treatment of abnormal cell growth
BRPI0511132A (pt)	2004-05-14	2007-11-27	Pfizer Prod Inc	derivados de pirimidina e composição farmacêutica compreendendo os mesmos
US8258145B2 (en)	2005-01-03	2012-09-04	Myrexis, Inc.	Method of treating brain cancer
US7423042B2 (en) *	2005-03-25	2008-09-09	Glaxo Group Limited	Compounds
CN101495475A (zh)	2005-03-25	2009-07-29	葛兰素集团有限公司	制备吡啶并[2,3-d]嘧啶-7-酮和3,4-二氢嘧啶并[4,5-d]嘧啶-2(1H)-酮衍生物的方法
AR053450A1 (es)	2005-03-25	2007-05-09	Glaxo Group Ltd	Derivados de 3,4-dihidro-pirimido(4,5-d)pirimidin-2-(1h)-ona 1,5,7 trisustituidos como inhibidores de la quinasa p38
MY145343A (en) *	2005-03-25	2012-01-31	Glaxo Group Ltd	Novel compounds
US8940764B2 (en)	2005-05-26	2015-01-27	Aldexa Therapeutics, Inc.	Compositions and methods of treating retinal disease
WO2007081517A2 (en)	2005-12-21	2007-07-19	Abbott Laboratories	Anti-viral compounds
AU2006330924B2 (en)	2005-12-21	2012-03-15	Abbvie Inc.	Anti-viral compounds
EP2345652A1 (en)	2005-12-21	2011-07-20	Abbott Laboratories	Antiviral compounds
WO2007076035A2 (en)	2005-12-21	2007-07-05	Abbott Laboratories	Anti-viral compounds
CN101384591A (zh) *	2005-12-21	2009-03-11	艾博特公司	抗病毒化合物
TWI399380B (zh)	2006-12-20	2013-06-21	Abbott Lab	抗病毒化合物
TWI557117B (zh)	2008-12-09	2016-11-11	吉李德科學股份有限公司	用於製備可用作類鐸受體調節劑之化合物的中間體化合物
WO2010096426A2 (en) *	2009-02-20	2010-08-26	Emory University	Compounds, compositions, methods of synthesis, and methods of treatment
WO2011031965A1 (en)	2009-09-14	2011-03-17	Gilead Sciences, Inc.	Modulators of toll-like receptors
US9814701B2 (en)	2009-12-11	2017-11-14	Aldeyra Therapeutics, Inc.	Compositions and methods for the treatment of macular degeneration
WO2012088266A2 (en)	2010-12-22	2012-06-28	Incyte Corporation	Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
ES2618003T3 (es)	2012-06-13	2017-06-20	Incyte Holdings Corporation	Compuestos tricíclicos sustituidos como inhibidores de FGFR
WO2014026125A1 (en)	2012-08-10	2014-02-13	Incyte Corporation	Pyrazine derivatives as fgfr inhibitors
US9266892B2 (en)	2012-12-19	2016-02-23	Incyte Holdings Corporation	Fused pyrazoles as FGFR inhibitors
HK1217439A1 (zh)	2013-01-23	2017-01-13	Aldeyra Therapeutics, Inc.	與毒性醛相關的疾病和治療
PT2986610T (pt)	2013-04-19	2018-03-09	Incyte Holdings Corp	Heterociclos bicíclicos como inibidores de fgfr
US10882868B2 (en)	2014-05-15	2021-01-05	Hoffmann-La Roche Inc.	Compounds for treating spinal muscular atrophy
PT3143025T (pt) *	2014-05-15	2019-12-03	Hoffmann La Roche	Compostos para tratamento da atrofia muscular espinhal
TW202412806A (zh)	2014-07-11	2024-04-01	美商基利科學股份有限公司	用於治療HIV之toll樣受體調節劑
CN110305133A (zh)	2014-09-16	2019-10-08	吉利德科学公司	Toll样受体调节剂的固体形式
NZ729526A (en)	2014-09-16	2018-05-25	Gilead Sciences Inc	Methods of preparing toll-like receptor modulators
US10851105B2 (en)	2014-10-22	2020-12-01	Incyte Corporation	Bicyclic heterocycles as FGFR4 inhibitors
MA41551A (fr)	2015-02-20	2017-12-26	Incyte Corp	Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
US9580423B2 (en)	2015-02-20	2017-02-28	Incyte Corporation	Bicyclic heterocycles as FGFR4 inhibitors
KR102632018B1 (ko)	2015-02-20	2024-02-02	인사이트 홀딩스 코포레이션	Fgfr 저해제로서의 이환식 복소환
EP3317278B1 (en)	2015-07-01	2021-04-14	Crinetics Pharmaceuticals, Inc.	Somatostatin modulators and uses thereof
US10550085B2 (en)	2015-08-21	2020-02-04	Aldeyra Therapeutics, Inc.	Deuterated compounds and uses thereof
PL3413892T3 (pl)	2016-02-12	2022-06-13	Cytokinetics, Incorporated	Pochodne tetrahydroizochinoliny
AR111960A1 (es)	2017-05-26	2019-09-04	Incyte Corp	Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
WO2019023278A1 (en)	2017-07-25	2019-01-31	Crinetics Pharmaceuticals, Inc.	MODULATORS OF SOMATOSTATIN AND USES THEREOF
EP3694500A4 (en) *	2017-10-10	2021-06-30	Aldeyra Therapeutics, Inc.	TREATMENT OF INFLAMMATORY DISORDERS
SG11202010882XA (en)	2018-05-04	2020-11-27	Incyte Corp	Salts of an fgfr inhibitor
BR112020022392A2 (pt)	2018-05-04	2021-02-02	Incyte Corporation	formas sólidas de um inibidor de fgfr e processos para preparação das mesmas
US12006298B2 (en)	2018-08-06	2024-06-11	Aldeyra Therapeutics, Inc.	Polymorphic compounds and uses thereof
CA3113462A1 (en)	2018-09-25	2020-04-02	Aldeyra Therapeutics, Inc.	Formulations of reproxalap for the treatment of dry eye disease
US11628162B2 (en)	2019-03-08	2023-04-18	Incyte Corporation	Methods of treating cancer with an FGFR inhibitor
JP7706758B2 (ja)	2019-03-26	2025-07-14	アルデイラセラピューティクス，インコーポレイテッド	眼科用製剤およびその使用
CN113784954A (zh)	2019-05-02	2021-12-10	奥尔德拉医疗公司	多晶型化合物和其用途
US12098132B2 (en)	2019-05-02	2024-09-24	Aldeyra Therapeutics, Inc.	Process for preparation of aldehyde scavenger and intermediates
WO2021007269A1 (en)	2019-07-09	2021-01-14	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
US12122767B2 (en)	2019-10-01	2024-10-22	Incyte Corporation	Bicyclic heterocycles as FGFR inhibitors
PH12022550892A1 (en)	2019-10-14	2023-05-03	Incyte Corp	Bicyclic heterocycles as fgfr inhibitors
WO2021076728A1 (en)	2019-10-16	2021-04-22	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
CA3162010A1 (en)	2019-12-04	2021-06-10	Incyte Corporation	Derivatives of an fgfr inhibitor
JP7720840B2 (ja)	2019-12-04	2025-08-08	インサイト・コーポレイション	Ｆｇｆｒ阻害剤としての三環式複素環
WO2021146424A1 (en)	2020-01-15	2021-07-22	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
EP4149470A4 (en)	2020-05-13	2024-04-24	Aldeyra Therapeutics, Inc.	Pharmaceutical formulations and uses thereof
US12065494B2 (en)	2021-04-12	2024-08-20	Incyte Corporation	Combination therapy comprising an FGFR inhibitor and a Nectin-4 targeting agent
WO2022261160A1 (en)	2021-06-09	2022-12-15	Incyte Corporation	Tricyclic heterocycles as fgfr inhibitors
JP2024522188A (ja)	2021-06-09	2024-06-11	インサイト・コーポレイション	Ｆｇｆｒ阻害剤としての三環式ヘテロ環

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4605642A (en)	1984-02-23	1986-08-12	The Salk Institute For Biological Studies	CRF antagonists
US5063245A (en)	1990-03-28	1991-11-05	Nova Pharmaceutical Corporation	Corticotropin-releasing factor antagonism compounds
GB9300059D0 (en) *	1992-01-20	1993-03-03	Zeneca Ltd	Quinazoline derivatives
TW370529B (en) *	1992-12-17	1999-09-21	Pfizer	Pyrazolopyrimidines
EP0674641B1 (en) *	1992-12-17	1999-03-03	Pfizer Inc.	Pyrrolopyrimidines as crf antagonists
IL112249A (en)	1994-01-25	2001-11-25	Warner Lambert Co	Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
TW530047B (en) *	1994-06-08	2003-05-01	Pfizer	Corticotropin releasing factor antagonists
DE69510940T2 (de) *	1994-06-16	1999-11-11	Pfizer Inc., New York	Pyrazolo und pyrrolopyridine
JP2898887B2 (ja) *	1994-08-31	1999-06-02	沖電気工業株式会社	Ｉｃカードの読み取り装置
EP0729758A3 (en) *	1995-03-02	1997-10-29	Pfizer	Pyrazolopyrimidines and pyrrolopyrimidines for the treatment of neuronal and other diseases
ATE182148T1 (de) *	1995-05-12	1999-07-15	Neurogen Corp	Neue deazapurinderivate; eine neue klasse von crf1-spezifischen liganden
US6403599B1 (en) *	1995-11-08	2002-06-11	Pfizer Inc	Corticotropin releasing factor antagonists
ES2200039T3 (es) *	1995-12-08	2004-03-01	Pfizer Inc.	Derivados heterociclicos sustituidos como antagonistas de crf.
BR9707391A (pt)	1996-02-07	1999-07-20	Janssen Pharmaceutica Nv	Pirazolpirimidinas como antagonistas de receptor de crf
TW477787B (en)	1996-08-27	2002-03-01	Pfizer	Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same

1997
- 1997-07-23 KR KR1019997001005A patent/KR20000029843A/ko not_active Abandoned
- 1997-07-23 TR TR1999/00228T patent/TR199900228T2/xx unknown
- 1997-07-23 CA CA002262692A patent/CA2262692C/en not_active Expired - Fee Related
- 1997-07-23 WO PCT/IB1997/000918 patent/WO1998005661A1/en active IP Right Grant
- 1997-07-23 YU YU5399A patent/YU5399A/sh unknown
- 1997-07-23 ES ES97929472T patent/ES2191183T3/es not_active Expired - Lifetime
- 1997-07-23 US US09/242,076 patent/US6492520B1/en not_active Expired - Fee Related
- 1997-07-23 AU AU33563/97A patent/AU709203B2/en not_active Ceased
- 1997-07-23 CZ CZ1999411A patent/CZ292806B6/cs not_active IP Right Cessation
- 1997-07-23 JP JP50775498A patent/JP3345021B2/ja not_active Expired - Fee Related
- 1997-07-23 PL PL97331602A patent/PL331602A1/xx unknown
- 1997-07-23 IL IL12818897A patent/IL128188A0/xx unknown
- 1997-07-23 DE DE69719193T patent/DE69719193T2/de not_active Expired - Fee Related
- 1997-07-23 BR BR9710808A patent/BR9710808A/pt not_active Application Discontinuation
- 1997-07-23 AT AT97929472T patent/ATE232863T1/de not_active IP Right Cessation
- 1997-07-23 SK SK140-99A patent/SK14099A3/sk unknown
- 1997-07-23 EA EA199900083A patent/EA003188B1/ru not_active IP Right Cessation
- 1997-07-23 NZ NZ333727A patent/NZ333727A/xx unknown
- 1997-07-23 EP EP97929472A patent/EP0920429B1/en not_active Expired - Lifetime
- 1997-07-23 DK DK97929472T patent/DK0920429T3/da active
- 1997-07-23 CN CN97197079A patent/CN1093130C/zh not_active Expired - Fee Related
- 1997-07-31 AP APAP/P/1997/001052A patent/AP1096A/en active
- 1997-08-04 TW TW086111115A patent/TW550265B/zh active
- 1997-08-04 GT GT199700089A patent/GT199700089A/es unknown
- 1997-08-05 PA PA19978435201A patent/PA8435201A1/es unknown
- 1997-08-05 CO CO97044966A patent/CO4900060A1/es unknown
- 1997-08-05 PE PE1997000679A patent/PE97098A1/es not_active Application Discontinuation
- 1997-08-05 UY UY24655A patent/UY24655A1/es not_active IP Right Cessation
- 1997-08-05 ID IDP972708A patent/ID17980A/id unknown
- 1997-08-05 ZA ZA976954A patent/ZA976954B/xx unknown
- 1997-08-05 AR ARP970103560A patent/AR008829A1/es not_active Application Discontinuation
- 1997-08-06 DZ DZ970139A patent/DZ2289A1/fr active
- 1997-08-06 TN TNTNSN97135A patent/TNSN97135A1/fr unknown
- 1997-08-06 HR HR970432A patent/HRP970432B1/xx not_active IP Right Cessation
- 1997-08-06 MA MA24755A patent/MA24296A1/fr unknown
- 1997-08-25 SA SA97180334A patent/SA97180334A/ar unknown
1999
- 1999-01-19 IS IS4948A patent/IS4948A/is unknown
- 1999-02-03 BG BG103143A patent/BG103143A/xx unknown
- 1999-02-03 OA OA9900024A patent/OA10970A/en unknown
- 1999-02-05 NO NO19990544A patent/NO313293B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20000029843A (ko)	2000-05-25
EA199900083A1 (ru)	1999-08-26
IS4948A (is)	1999-01-19
HRP970432A2 (en)	1998-08-31
NO990544D0 (no)	1999-02-05
GT199700089A (es)	1999-01-26
CN1227552A (zh)	1999-09-01
DE69719193D1 (de)	2003-03-27
ZA976954B (en)	1999-02-05
CZ41199A3 (cs)	2000-01-12
OA10970A (en)	2001-11-05
ATE232863T1 (de)	2003-03-15
NO313293B1 (no)	2002-09-09
YU5399A (sh)	2002-03-18
PE97098A1 (es)	1999-01-12
AP1096A (en)	2002-08-26
ID17980A (id)	1998-02-12
TR199900228T2 (xx)	1999-03-22
CA2262692C (en)	2002-06-11
EP0920429B1 (en)	2003-02-19
CO4900060A1 (es)	2000-03-27
WO1998005661A1 (en)	1998-02-12
JP3345021B2 (ja)	2002-11-18
SA97180334A (ar)	2005-12-03
CN1093130C (zh)	2002-10-23
HK1021734A1 (en)	2000-06-30
CZ292806B6 (cs)	2003-12-17
UY24655A1 (es)	2000-09-29
AU3356397A (en)	1998-02-25
BG103143A (en)	1999-09-30
TNSN97135A1 (fr)	2005-03-15
CA2262692A1 (en)	1998-02-12
AP9701052A0 (en)	1997-10-31
US6492520B1 (en)	2002-12-10
JP2000501116A (ja)	2000-02-02
AU709203B2 (en)	1999-08-26
NZ333727A (en)	2000-09-29
IL128188A0 (en)	1999-11-30
HRP970432B1 (en)	2002-10-31
DK0920429T3 (da)	2003-05-12
AR008829A1 (es)	2000-02-23
EP0920429A1 (en)	1999-06-09
ES2191183T3 (es)	2003-09-01
SK14099A3 (en)	2000-05-16
TW550265B (en)	2003-09-01
DE69719193T2 (de)	2003-09-25
PA8435201A1 (es)	1999-12-27
EA003188B1 (ru)	2003-02-27
PL331602A1 (en)	1999-08-02
DZ2289A1 (fr)	2002-12-25
MA24296A1 (fr)	1998-04-01
BR9710808A (pt)	1999-08-17

Publication	Publication Date	Title
NO990544D0 (no)	1999-02-05	Substituerte pyrido- eller pyrimido-inneholdende 6,6 eller 6,7-bycykliske derivater
IS4963A (is)	1999-01-29	Setnar 6,5-heteró-bísýklískar afleiður
DK0925298T3 (da)	2004-08-09	Substituerede 6,6-heterobicykliske derivater
PT901474E (pt)	2006-07-31	Derivados de aril-pirimidina.
DK1000048T3 (da)	2003-03-03	Substituerede 1,2,3,4-tetrahydronapthalenderivater
TR28098A (tr)	1996-01-08	1,2,4-okzadiazol türevleri.
ATE231847T1 (de)	2003-02-15	Substituierte 1,2,3,4- tetrahydronaphthalinderivate
FI952424L (fi)	1995-11-20	11,21-bisfenyyli-19-norpregaanijohdannaisia
TR27961A (tr)	1995-11-06	Sübstitüe edilmis 1,2,3,4 -tetrahidro-5-nitro-pirimidinler.
DK1015467T3 (da)	2004-05-03	6,9-brobundne erythromycinderivater
DE69814441D1 (de)	2003-06-12	6,11-verbrückte erythromycinderivate
DK0922050T3 (da)	2003-11-24	3-Descladinose-2,3-anhydroerythromycin-derivater
ATE227282T1 (de)	2002-11-15	2,4-diaminopyrimidin-derivate
TR199700354A3 (tr)	1997-11-21	Karbohidrat türevleri.
DE69714358D1 (de)	2002-09-05	9,10-disubstituierte campothecinderivate mit antitumoraktivität
DE69906149D1 (de)	2003-04-24	4,5-azolo-oxindole
TR28915A (tr)	1997-08-06	Naftokinon türevleri.
TR199700219A3 (tr)	1997-10-21	1,25-Dihidroksi-16, 22, 23-Trisdihidro-kolkalsiferol türevleri.
ES1034273Y (es)	1997-05-01	Maleta-expositor transformable, perfeccionada.
TR199700927A3 (tr)	1999-03-22	N-Benzilazolyum türevleri.
FI924324A0 (fi)	1992-09-25	Behaollare foer kornformigt, pulverformigt eller annat dylikt massgods.
ITRC960004A0 (it)	1996-05-20	Vergafa m.c.
FI941011A0 (fi)	1994-03-03	Balningspress, saerskilt foer balning av avfallspapplaodor o.d. returavfall
DZ2644A1 (fr)	2003-03-15	Triazolo-Ä3,4-aÜ-pyridazine substituées en 1,2,4.
FI911327A0 (fi)	1991-03-19	Behaollare foer pulverformigt, kornformigt eller annat dylikt massagods.

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