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ATE146081T1 - Konjugatimpfstoff für gruppe b-streptococcus - Google Patents

Konjugatimpfstoff für gruppe b-streptococcus

Info

Publication number
ATE146081T1
ATE146081T1 AT90915038T AT90915038T ATE146081T1 AT E146081 T1 ATE146081 T1 AT E146081T1 AT 90915038 T AT90915038 T AT 90915038T AT 90915038 T AT90915038 T AT 90915038T AT E146081 T1 ATE146081 T1 AT E146081T1
Authority
AT
Austria
Prior art keywords
streptococcus
group
conjugate vaccine
vaccine
protein
Prior art date
Application number
AT90915038T
Other languages
English (en)
Inventor
James L Michel
Dennis L Kasper
Frederick M Ausubel
Original Assignee
Gen Hospital Corp
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp, Brigham & Womens Hospital filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of ATE146081T1 publication Critical patent/ATE146081T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT90915038T 1989-09-15 1990-09-14 Konjugatimpfstoff für gruppe b-streptococcus ATE146081T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40803689A 1989-09-15 1989-09-15

Publications (1)

Publication Number Publication Date
ATE146081T1 true ATE146081T1 (de) 1996-12-15

Family

ID=23614587

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90915038T ATE146081T1 (de) 1989-09-15 1990-09-14 Konjugatimpfstoff für gruppe b-streptococcus

Country Status (22)

Country Link
EP (1) EP0491865B1 (de)
JP (2) JPH05500455A (de)
KR (1) KR0180559B1 (de)
AT (1) ATE146081T1 (de)
AU (1) AU641439B2 (de)
CA (2) CA2066221C (de)
DE (1) DE69029396T2 (de)
DK (1) DK0491865T3 (de)
ES (1) ES2097154T3 (de)
FI (1) FI105154B (de)
GR (1) GR1002294B (de)
HU (1) HU219327B (de)
IE (1) IE903349A1 (de)
IL (1) IL95578A (de)
NO (1) NO313908B1 (de)
NZ (1) NZ235316A (de)
PL (3) PL167882B1 (de)
PT (1) PT95316A (de)
RU (1) RU2113234C1 (de)
WO (1) WO1991004049A1 (de)
YU (1) YU176490A (de)
ZA (1) ZA907297B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648241A (en) * 1989-09-15 1997-07-15 The General Hospital Corporation Conjugate vaccine against group B streptococcus
DE69330464T2 (de) * 1992-09-24 2001-11-08 Brigham And Women's Hospital, Boston Gruppe b streptococcus typ ii und typ v polysaccharid-protein konjugate als impfstoffe
ZA937034B (en) * 1992-09-24 1995-06-23 Brigham & Womens Hospital Group B streptococcus type II and type V polysaccharide-protein conjugate vaccines
AU722078B2 (en) * 1992-11-02 2000-07-20 Brigham And Women's Hospital Conjugate vaccine against group B Streptococcus
IL107458A0 (en) * 1992-11-02 1994-02-27 Gen Hospital Corp Conjugate vaccine against group b streptococcus
US6015889A (en) * 1993-03-19 2000-01-18 Gunnar Lindahl Protein rib, a cell surface protein that confers immunity to many strains of the group B streptococcus: process for purification of the protein, reagent kit and pharmaceutical composition
CN1046291C (zh) * 1993-03-19 1999-11-10 G·林达尔 Rib蛋白、其纯化方法、检测试剂盒及药物组合物
US5439808A (en) * 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US5565204A (en) * 1994-08-24 1996-10-15 American Cyanamid Company Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
US5747287A (en) * 1995-04-28 1998-05-05 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US6284884B1 (en) 1995-06-07 2001-09-04 North American Vaccine, Inc. Antigenic group B streptococcus type II and type III polysaccharide fragments having a 2,5-anhydro-D-mannose terminal structure and conjugate vaccine thereof
CA2317029A1 (en) * 1997-12-31 1999-07-08 Seth H. Pincus A method of isolating a peptide which immunologically mimics microbial carbohydrates including group b streptococcal carbohydrates and the use thereof in a vaccine
RU2186389C1 (ru) * 2001-01-09 2002-07-27 Государственное федеральное учреждение науки Уральский научно-исследовательский институт травматологии и ортопедии Способ культивирования h. influenzae из носоглоточной слизи (варианты)
RU2261109C1 (ru) * 2004-01-05 2005-09-27 ГНУ Научно-исследовательский институт пушного звероводства и кролиководства им. В.А. Афанасьева Штамм бактерий streptococcus agalactiae №71 для изготовления вакцин против стрептококкоза пушных зверей
CA2591510A1 (en) * 2004-12-22 2006-06-29 Novartis Vaccines And Diagnostics, Inc. Group b streptococcus
RU2378374C2 (ru) * 2008-03-21 2010-01-10 Учреждение Российской академии медицинских наук Научно-исследовательский институт экспериментальной медицины Северо-Западного отделения РАМН Рекомбинантная днк, обеспечивающая получение рекомбинантного белка pb1, обладающего протективными свойствами в отношении streptococcus pyogenes и streptococcus agalactiae
RU2387715C2 (ru) * 2008-06-18 2010-04-27 Учреждение Российской Академии Медицинских Наук Научно-исследовательский институт экспериментальной медицины Северо-западного отделения РАМН (НИИЭМ СЗО РАМН) РЕКОМБИНАНТНЫЕ ДНК, ОБЕСПЕЧИВАЮЩИЕ ПОЛУЧЕНИЕ ПОЛИПЕПТИДОВ Р6, Р7, Р8, ОБЛАДАЮЩИХ ПРОТЕКТИВНЫМИ СВОЙСТВАМИ В ОТНОШЕНИИ STREPTOCOCCUS AGALACTIAE И СЕЛЕКТИВНО-СВЯЗЫВАЮЩИХ IgA

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4367222A (en) * 1980-06-09 1983-01-04 President And Fellows Of Harvard College Immune globulin specific to Group B streptococci
US4367223A (en) * 1980-06-09 1983-01-04 President And Fellows Of Harvard College Vaccine against Group B streptococci
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
NZ214503A (en) * 1984-12-20 1990-02-26 Merck & Co Inc Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates
DE3750139T2 (de) * 1986-04-16 1994-10-06 Brigham & Womens Hospital Bakterielle antigene, antikörper, impfstoffe und deren herstellung.
WO1989000583A1 (en) * 1987-07-17 1989-01-26 Xoma Corporation Improved immunotoxin therapies utilizing purified ricin a-chain species

Also Published As

Publication number Publication date
RU2113234C1 (ru) 1998-06-20
PL167444B1 (pl) 1995-09-30
NO313908B1 (no) 2002-12-23
PT95316A (pt) 1991-06-25
NO920942D0 (no) 1992-03-11
CA2066221A1 (en) 1991-03-16
EP0491865B1 (de) 1996-12-11
IE903349A1 (en) 1991-04-10
DE69029396D1 (de) 1997-01-23
GR900100692A (el) 1992-01-20
DK0491865T3 (da) 1997-06-02
EP0491865A4 (en) 1993-05-05
FI105154B (fi) 2000-06-30
CA2383393A1 (en) 1991-04-04
PL167882B1 (pl) 1995-11-30
AU6519090A (en) 1991-04-18
ES2097154T3 (es) 1997-04-01
KR0180559B1 (ko) 1999-03-20
ZA907297B (en) 1993-06-01
YU176490A (sh) 1992-12-21
EP0491865A1 (de) 1992-07-01
JP3447713B2 (ja) 2003-09-16
CA2066221C (en) 2002-07-23
DE69029396T2 (de) 1997-06-05
JP2001309795A (ja) 2001-11-06
PL168587B1 (pl) 1996-03-29
PL286898A1 (en) 1991-06-03
AU641439B2 (en) 1993-09-23
KR920703097A (ko) 1992-12-17
FI921111A0 (fi) 1992-03-13
GR1002294B (el) 1996-05-03
NZ235316A (en) 1992-11-25
JPH05500455A (ja) 1993-02-04
IL95578A (en) 1998-08-16
IL95578A0 (en) 1991-06-30
HUT63770A (en) 1993-10-28
WO1991004049A1 (en) 1991-04-04
HU219327B (en) 2001-03-28
NO920942L (no) 1992-05-12

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee