[go: up one dir, main page]

ATE168719T1 - Osteogene peptide - Google Patents

Osteogene peptide

Info

Publication number
ATE168719T1
ATE168719T1 AT91919612T AT91919612T ATE168719T1 AT E168719 T1 ATE168719 T1 AT E168719T1 AT 91919612 T AT91919612 T AT 91919612T AT 91919612 T AT91919612 T AT 91919612T AT E168719 T1 ATE168719 T1 AT E168719T1
Authority
AT
Austria
Prior art keywords
osteogenic
methods
proteins
polypeptide chains
osteogenic devices
Prior art date
Application number
AT91919612T
Other languages
English (en)
Inventor
Hermann Oppermann
Engin Ozkaynak
David C Reuger
Thangavel Kuberasampath
Original Assignee
Stryker Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stryker Corp filed Critical Stryker Corp
Application granted granted Critical
Publication of ATE168719T1 publication Critical patent/ATE168719T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
AT91919612T 1990-10-18 1991-10-18 Osteogene peptide ATE168719T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59954390A 1990-10-18 1990-10-18

Publications (1)

Publication Number Publication Date
ATE168719T1 true ATE168719T1 (de) 1998-08-15

Family

ID=24400058

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91919612T ATE168719T1 (de) 1990-10-18 1991-10-18 Osteogene peptide

Country Status (9)

Country Link
EP (1) EP0643767B1 (de)
JP (2) JPH07500487A (de)
AT (1) ATE168719T1 (de)
AU (1) AU663689B2 (de)
CA (1) CA2094027C (de)
DE (1) DE69129865T2 (de)
DK (1) DK0643767T3 (de)
ES (1) ES2120964T3 (de)
WO (1) WO1992007073A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US5688678A (en) * 1990-05-16 1997-11-18 Genetics Institute, Inc. DNA encoding and methods for producing BMP-8 proteins
US7378392B1 (en) 1990-05-16 2008-05-27 Genetics Institute, Llc Bone and cartilage inductive proteins
JPH06500991A (ja) * 1990-05-16 1994-01-27 ジェネティックス・インスティテュート・インコーポレイテッド 骨および軟骨誘導蛋白質
US6090776A (en) * 1991-03-11 2000-07-18 Creative Bio Molecules, Inc. Morphogen treatment of organ implants
US6194376B1 (en) 1991-03-11 2001-02-27 Creative Biomolecules, Inc. Method for modulating inflammatory response comprising administering morphogen
US5652118A (en) * 1991-03-11 1997-07-29 Creative Biomolecules, Inc. Nucleic acid encoding a novel morphogenic protein, OP-3
US6395883B1 (en) 1991-03-11 2002-05-28 Curis, Inc. Soluble morphogenic protein complex compositions of matter
US5739107A (en) * 1991-03-11 1998-04-14 Creative Biomolecules, Inc. Morphogen treatment of gastrointestinal ulcers
US6077823A (en) * 1991-03-11 2000-06-20 Creative Biomolecules, Inc. Method for reducing tissue damage associated with ischemia-reperfusion or hypoxia injury
WO1993000432A1 (en) * 1991-06-25 1993-01-07 Genetics Institute, Inc. Bmp-9 compositions
US6287816B1 (en) 1991-06-25 2001-09-11 Genetics Institute, Inc. BMP-9 compositions
WO1993004692A1 (en) * 1991-08-30 1993-03-18 Creative Biomolecules, Inc. Morphogen-induced modulation of inflammatory response
ATE287949T1 (de) * 1992-07-31 2005-02-15 Stryker Corp Löslicher komplex morphogener proteine und zusammensetzungen davon
JP3645258B2 (ja) * 1993-01-12 2005-05-11 ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン 増殖分化因子−５
US5986058A (en) 1993-07-09 1999-11-16 The Johns Hopkins University School Of Medicine Polynucleotide encoding growth differentiation factor-7 and protein encoded thereby
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
JP3717930B2 (ja) 1993-12-07 2005-11-16 ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー Ｂｍｐ−１２、ｂｍｐ−１３およびそれらの腱誘導組成物
US6040431A (en) 1995-06-07 2000-03-21 Stryker Corporation Single chain analogs of the TGF-β superfamily (morphons)
US5968752A (en) * 1995-08-14 1999-10-19 Creative Biomolecules, Inc. Method for identifying an OP-1 analog which binds an ALK-1 receptor
WO1997026277A2 (en) * 1996-01-22 1997-07-24 Creative Biomolecules, Inc. Morphogen analogs and methods for producing them
ATE493141T1 (de) 1996-03-22 2011-01-15 Stryker Corp Verfahren zur verbesserten funktionellen erholung der motorischen koordiination, der sprache oder der sinneswahrnehmung nach trauma oder ischämie des zns
US6034062A (en) * 1997-03-13 2000-03-07 Genetics Institute, Inc. Bone morphogenetic protein (BMP)-9 compositions and their uses
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
WO2001028602A1 (en) 1999-10-15 2001-04-26 Genetics Institute, Inc. Formulations of hyaluronic acid for delivery of osteogenic proteins
EP1266961A4 (de) * 2000-03-16 2004-12-08 Kyowa Hakko Kogyo Kk Leberheilender faktor
DK1399023T3 (da) 2001-06-01 2008-08-18 Wyeth Corp Sammensætninger til systemisk indgivelse af sekvenser, der koder for knoglemorfogenese-proteiner
BR0214275A (pt) 2001-11-19 2004-09-21 Scil Technology Gmbh Dispositivo tendo propriedades osteocondutora e osteoindutora
JP4358741B2 (ja) 2002-09-10 2009-11-04 スキール テヒノロギー ゲーエムベーハー 低酸素濃度下において骨誘導性タンパク質で被覆された金属インプラント
ATE478008T1 (de) 2004-03-10 2010-09-15 Scil Technology Gmbh Überzogene implantate, ihre herstellung und verwendung davon
WO2007056614A1 (en) * 2005-11-14 2007-05-18 Merial Limited Gene therapy for renal failure
WO2023272658A1 (zh) * 2021-06-30 2023-01-05 北京泽勤生物医药有限公司 增强成骨细胞活性的多肽及其在治疗骨科疾病中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE243254T1 (de) * 1988-04-08 2003-07-15 Stryker Corp Biosynthetische knochenbildende proteine, und sie enthaltende knochenbildende vorrichtungen
ES2113857T3 (es) * 1989-03-28 1998-05-16 Genetics Inst Composiciones osteoinductoras.

Also Published As

Publication number Publication date
DE69129865D1 (de) 1998-08-27
CA2094027C (en) 2001-12-25
WO1992007073A1 (en) 1992-04-30
CA2094027A1 (en) 1992-04-19
ES2120964T3 (es) 1998-11-16
EP0643767B1 (de) 1998-07-22
JPH07500487A (ja) 1995-01-19
EP0643767A1 (de) 1995-03-22
JPH11262395A (ja) 1999-09-28
AU8900091A (en) 1992-05-20
AU663689B2 (en) 1995-10-19
DK0643767T3 (da) 1999-04-26
DE69129865T2 (de) 1999-03-04

Similar Documents

Publication Publication Date Title
ATE168719T1 (de) Osteogene peptide
ATE134647T1 (de) Osteogene vorrichtungen
ATE167486T1 (de) Osteogene vorrichtungen
DE69016655D1 (de) Biologisch aktive polypeptide, die auf transformierten wachstumsfaktor-beta-sequenzen basieren.
DE3856265D1 (de) Varianten des pankreatischen Rinder-Trypsininhibitors, deren Herstellung und Verwendung
DE69939330D1 (de) Wachstumsfaktor-homologe zvegf-3
NO992158L (no) Nukleinsyre- og aminosyresekvenser forbundet med Heliobacter Pylori og vaksinepreparater av disse.
ATE166231T1 (de) Produktion und verwendung von antihelmintischen substanzen und schützenden immunogenen
ES2044928T3 (es) Enzima alfa-amidante en terminal c y procedimiento para la produccion y el uso del mismo.
DE59109235D1 (de) Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
DE3873273D1 (de) Verfahren zur selektiven spaltung von fusionsproteinen.
DK34590D0 (da) Biologisk aktive molekyler
DE69534738D1 (de) Leukocyten-aktivierender Faktor
DE69613086D1 (de) Antigenen Peptide mit Glycinsubstitution
DK0540560T3 (da) Ancrod-lignende proteiner, fremstilling og anvendelse deraf
DE3876240D1 (de)
DE60138885D1 (de) Polypeptide mit aktivität der stimulierung von neutrophilen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee