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ATE210640T1 - Modifizierte mehrfach ungesättigte fettsäuren - Google Patents

Modifizierte mehrfach ungesättigte fettsäuren

Info

Publication number
ATE210640T1
ATE210640T1 AT95933988T AT95933988T ATE210640T1 AT E210640 T1 ATE210640 T1 AT E210640T1 AT 95933988 T AT95933988 T AT 95933988T AT 95933988 T AT95933988 T AT 95933988T AT E210640 T1 ATE210640 T1 AT E210640T1
Authority
AT
Austria
Prior art keywords
fatty acid
polyunsaturated fatty
oxa
provides
fatty acids
Prior art date
Application number
AT95933988T
Other languages
English (en)
Inventor
Antonio Ferrante
Alfred Poulos
Christopher John Easton
Michael Joseph Pitt
Thomas Alistair Robertson
Deborah Ann Rathjen
Original Assignee
Peptide Technology Ltd
Womens & Childrens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPM8781A external-priority patent/AUPM878194A0/en
Priority claimed from AUPM9066A external-priority patent/AUPM906694A0/en
Application filed by Peptide Technology Ltd, Womens & Childrens Hospital filed Critical Peptide Technology Ltd
Application granted granted Critical
Publication of ATE210640T1 publication Critical patent/ATE210640T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C409/00Peroxy compounds
    • C07C409/02Peroxy compounds the —O—O— group being bound between a carbon atom, not further substituted by oxygen atoms, and hydrogen, i.e. hydroperoxides
    • C07C409/04Peroxy compounds the —O—O— group being bound between a carbon atom, not further substituted by oxygen atoms, and hydrogen, i.e. hydroperoxides the carbon atom being acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C409/00Peroxy compounds
    • C07C409/16Peroxy compounds the —O—O— group being bound between two carbon atoms not further substituted by oxygen atoms, i.e. peroxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C409/00Peroxy compounds
    • C07C409/40Peroxy compounds containing nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C409/00Peroxy compounds
    • C07C409/42Peroxy compounds containing sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/60Unsaturated compounds containing ether groups, groups, groups, or groups the non-carboxylic part of the ether being unsaturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708Ethers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT95933988T 1994-10-13 1995-10-13 Modifizierte mehrfach ungesättigte fettsäuren ATE210640T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPM8781A AUPM878194A0 (en) 1994-10-13 1994-10-13 Modified fatty acids in the treatment of inflammation
AUPM9066A AUPM906694A0 (en) 1994-10-26 1994-10-26 Novel compounds for treating malaria and other diseases
PCT/AU1995/000677 WO1996011908A1 (en) 1994-10-13 1995-10-13 Modified polyunsaturated fatty acids

Publications (1)

Publication Number Publication Date
ATE210640T1 true ATE210640T1 (de) 2001-12-15

Family

ID=25644792

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95933988T ATE210640T1 (de) 1994-10-13 1995-10-13 Modifizierte mehrfach ungesättigte fettsäuren

Country Status (9)

Country Link
US (1) US6376688B1 (de)
EP (1) EP0869941B1 (de)
JP (1) JPH10507179A (de)
KR (1) KR100463709B1 (de)
CN (1) CN1088058C (de)
AT (1) ATE210640T1 (de)
CA (1) CA2202503C (de)
DE (1) DE69524639T2 (de)
WO (1) WO1996011908A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997038688A1 (en) 1996-04-12 1997-10-23 Peptide Technology Pty. Limited Methods of treating immunopathologies using polyunsaturated fattyacids
DE19649869A1 (de) * 1996-12-02 1998-06-04 Biotechnolog Forschung Gmbh Ungesättigte aliphatische Carbonsäuren (Maracenine), Herstellungsverfahren und Mittel
AU784116B2 (en) * 1999-09-17 2006-02-09 Peplin Biolipids Pty Ltd Anti-cancer nitro- and thia-fatty acids
AUPQ291499A0 (en) * 1999-09-17 1999-10-07 Women's And Children's Hospital Adelaide Novel nitro and sulphur containing compounds
NO328803B1 (no) * 2000-03-03 2010-05-18 Thia Medica Nye fettsyreanaloger
NO20006008L (no) * 2000-11-28 2002-05-29 Thia Medica As Fettsyreanaloger for behandling av inflammatoriske og autoimmune sykdommer
AU2002352726A1 (en) 2001-11-15 2003-06-10 Galileo Laboratories, Inc. Formulations and methods for treatment or amelioration of inflammatory conditions
US20040002514A1 (en) * 2002-06-14 2004-01-01 Alcon, Inc. Topical use of hydroxyeicosatetraenoic acid compounds to treat psoriasis
EP1583527A1 (de) 2002-06-14 2005-10-12 Alcon, Inc. Verwendung von hydroxyeicosatetraensäure verbindungen zur behandlung augenentzendungen
WO2004000854A1 (en) 2002-06-20 2003-12-31 Ic Vec Limited Sulfur-containing phospholipid derivatives
EP1718602A4 (de) * 2004-01-30 2007-12-12 Peplin Biolipids Pty Ltd Therapeutische und trägermoleküle
WO2007131959A1 (en) * 2006-05-12 2007-11-22 Nuplex Resins B.V. Aqueous dispersion of an auto-oxidatively drying polyurethane
BRPI0717972A2 (pt) * 2006-11-01 2013-11-12 Pronova Biopharma Norge As Lipídeos de ômega-3 alfa-substituídos que são ativadores ou moduladores do receptor ativado por proliferadores de peroxissoma (ppar)
US20100104546A1 (en) * 2007-02-05 2010-04-29 Children, Youth And Women's Health Service Modulators of antigen-dependent t cell proliferation
WO2009017802A1 (en) 2007-08-01 2009-02-05 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Nitro-fattyacid modulation of type ii diabetes
WO2009134383A2 (en) 2008-05-01 2009-11-05 Complexa Inc. Vinyl substituted fatty acids
GB2460056A (en) * 2008-05-14 2009-11-18 Arab Science & Technology Foun Compositions comprising omega-6 fatty acids for use in treating schistosomiasis
EP2299997A4 (de) 2008-06-19 2012-01-11 Univ Utah Res Found Verwendung von nitrierten lipiden zur behandlung von nebenwirkungen von toxischen medizinischen therapien
US20140024713A1 (en) 2008-06-19 2014-01-23 University Of Utah Research Foundation Use of nitrated lipids for treatment of side effects of toxic medical therapies
EP2147910A1 (de) * 2008-07-15 2010-01-27 Pronova BioPharma Norge AS Neue Lipid-Verbindungen
EP2208720A1 (de) 2009-01-13 2010-07-21 Max-Delbrück-Centrum für Molekulare Medizin (MDC) Neuartige Eicosanoidderivate
EP2427415B1 (de) 2009-05-08 2019-03-20 Basf As Mehrfach ungesättigte fettsäuren zur behandlung von erkrankungen im zusammenhang mit herz-kreislauf-, stoffwechsel- und entzündungspathologie
US9066902B2 (en) 2009-07-31 2015-06-30 University of Pittsburgh—of the Commonwealth System of Higher Education Fatty acids as anti-inflammatory agents
EP2483233A4 (de) * 2009-10-02 2013-08-14 Complexa Inc Heteroatom mit substituierten fettsäuren
MY170076A (en) 2010-11-05 2019-07-03 Pronova Biopharma Norge As Methods of treatment using lipid compounds
EP2744491B1 (de) 2011-08-19 2020-07-29 The University of Utah Research Foundation Kombinationstherapie mit nitrierten lipiden und inhibitoren des renin-angiotensin-aldosteron-systems
JP6537980B2 (ja) 2013-02-28 2019-07-03 プロノヴァ・バイオファーマ・ノルゲ・アーエスPronova BioPharma Norge AS 脂質化合物、トリグリセリドおよび界面活性剤を含む組成物、ならびにその使用方法
WO2015063617A2 (en) * 2013-10-29 2015-05-07 Dignity Sciences Limited Methods of making 15-hydroxy fatty acid derivatives
US20180104201A1 (en) 2015-04-28 2018-04-19 Pronova Biopharma Norge As Use of structurally enhanced fatty acids containing sulphur for preventing and or treating non alcoholic steatohepatitis
EP3303339B1 (de) 2015-07-07 2021-01-13 H. Lundbeck A/S Pde9-inhibitoren mit imidazotriazinon-backbone und imidazopyrazinon-backbone zur behandlung von peripheren erkrankungen
MX2018004043A (es) 2015-10-02 2018-11-09 Complexa Inc Prevencion, tratamiento y reversion de enfermedad usando cantidades terapeuticamente efectivas de acidos grasos activados.
GB201521085D0 (en) * 2015-11-30 2016-01-13 Biozep As Use
US11111222B2 (en) 2016-06-23 2021-09-07 The Regents Of The University Of Michigan Hydroxyeicosatrienoic acid compounds and their use as therapeutic agents
HUE069832T2 (hu) 2017-12-06 2025-04-28 Basf As Zsírsav-származékok a nem alkoholos steatohepatitis kezelésére
WO2019226944A1 (en) 2018-05-25 2019-11-28 Imara Inc. Monohydrate and crystalline forms of 6-[(3s,4s)-4-methyl-1- (pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl- 7h-imid azo [1,5- a] pyrazin-8-one
CN119679736A (zh) 2018-08-31 2025-03-25 卡都瑞恩医药公司 用于治疗镰状细胞病的pde9抑制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6372648A (ja) * 1986-09-16 1988-04-02 Sumitomo Pharmaceut Co Ltd 新規不飽和脂肪酸誘導体
GB8813012D0 (en) * 1988-06-02 1988-07-06 Norsk Hydro As Non-b-oxidizable fatty acid analogues to reduce concentration of cholesterol & triglycerides in blood of mammals
JPH06511479A (ja) * 1991-06-24 1994-12-22 ウィメンズ アンド チルドレンズ ホスピタル マラリアおよびその他の疾患を治療するための方法および組成物
WO1994022848A1 (en) * 1993-03-29 1994-10-13 Pace Asciak Cecil R Hepoxilin analogs useful as anti-inflammatory agents
US5767156A (en) * 1993-10-06 1998-06-16 Peptide Technology Limited Polyunsaturated fatty acids and uses thereof

Also Published As

Publication number Publication date
EP0869941B1 (de) 2001-12-12
DE69524639T2 (de) 2002-08-08
EP0869941A4 (de) 1998-10-14
EP0869941A1 (de) 1998-10-14
WO1996011908A1 (en) 1996-04-25
JPH10507179A (ja) 1998-07-14
CA2202503A1 (en) 1996-04-25
CN1088058C (zh) 2002-07-24
DE69524639D1 (de) 2002-01-24
KR970707088A (ko) 1997-12-01
KR100463709B1 (ko) 2005-08-04
CA2202503C (en) 2008-07-15
CN1163609A (zh) 1997-10-29
US6376688B1 (en) 2002-04-23

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties