ATE229072T1 - Für den vorläufer des für die tumorabstossung verantwortlichen antigens mage-3 kodierendes, isoliertes nukleinsäuremolekül und seine verwendung - Google Patents
Für den vorläufer des für die tumorabstossung verantwortlichen antigens mage-3 kodierendes, isoliertes nukleinsäuremolekül und seine verwendungInfo
- Publication number
- ATE229072T1 ATE229072T1 AT94912246T AT94912246T ATE229072T1 AT E229072 T1 ATE229072 T1 AT E229072T1 AT 94912246 T AT94912246 T AT 94912246T AT 94912246 T AT94912246 T AT 94912246T AT E229072 T1 ATE229072 T1 AT E229072T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- acid molecule
- precursor
- responsible
- tumor rejection
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Casings For Electric Apparatus (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/037,230 US6235525B1 (en) | 1991-05-23 | 1993-03-26 | Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-3 and uses thereof |
| PCT/US1994/002877 WO1994023031A1 (en) | 1993-03-26 | 1994-03-17 | Isolated nucleic acid molecules coding for tumor rejection antigen precursor mage-3 and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE229072T1 true ATE229072T1 (de) | 2002-12-15 |
Family
ID=21893179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94912246T ATE229072T1 (de) | 1993-03-26 | 1994-03-17 | Für den vorläufer des für die tumorabstossung verantwortlichen antigens mage-3 kodierendes, isoliertes nukleinsäuremolekül und seine verwendung |
Country Status (15)
| Country | Link |
|---|---|
| US (6) | US6235525B1 (de) |
| EP (1) | EP0690915B1 (de) |
| JP (1) | JP3594307B2 (de) |
| KR (1) | KR100288749B1 (de) |
| CN (1) | CN1110556C (de) |
| AT (1) | ATE229072T1 (de) |
| AU (1) | AU685790B2 (de) |
| CA (1) | CA2159098C (de) |
| DE (1) | DE69431834T2 (de) |
| FI (1) | FI954536A7 (de) |
| NO (1) | NO953699L (de) |
| NZ (1) | NZ263693A (de) |
| TW (1) | TW432111B (de) |
| WO (1) | WO1994023031A1 (de) |
| ZA (1) | ZA941644B (de) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5925729A (en) * | 1991-05-23 | 1999-07-20 | Ludwig Institute For Cancer Research | Tumor rejection antigen precursors, tumor rejection antigens and uses thereof |
| USRE40089E1 (en) * | 1991-05-23 | 2008-02-19 | Ludwig Institute For Cancer Research | Nucleic acid molecules encoding the MAGE-1 tumor rejection antigen precursor |
| US6060257A (en) * | 1994-06-03 | 2000-05-09 | Ludwig Institute For Cancer Research | Tumor rejection antigens presented by HLA-B44 molecules, and uses thereof |
| US5587289A (en) * | 1995-03-14 | 1996-12-24 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules which are members of the MAGE-Xp family and uses thereof |
| AU7440196A (en) * | 1995-10-12 | 1997-04-30 | Chiron Corporation | Baboon mage-3 homologs, dna encoding the homologs, and a process for their use |
| UY24367A1 (es) * | 1995-11-23 | 2000-10-31 | Boehringer Ingelheim Int | Vacunas contra tumores y procedimiento para su produccion |
| CO4600681A1 (es) | 1996-02-24 | 1998-05-08 | Boehringer Ingelheim Pharma | Composicion farmaceutica para la modulacion inmunitaria |
| FR2746110B1 (fr) * | 1996-03-14 | 1998-04-17 | Methode de traitement par therapie genique des tumeurs humaines et virus recombinants correspondants | |
| US6027924A (en) * | 1997-04-25 | 2000-02-22 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecule coding for tumor rejection antigen precursor MAGE-C1 and uses thereof |
| US6291430B1 (en) | 1997-09-12 | 2001-09-18 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
| US6716809B1 (en) | 1997-09-12 | 2004-04-06 | Ludwig Institute For Cancer Research | Mage-A3 peptides presented by HLA class molecules |
| US5965535A (en) | 1997-09-12 | 1999-10-12 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
| SI1659179T1 (sl) | 1998-02-05 | 2011-10-28 | Glaxosmithkline Biolog Sa | S tumorjem povezani antigenski derivati iz MAGE druĹľine in zaporedja nukleinskih kislin, ki jih kodirajo, uporabni za pripravo fuzijskih proteinov in sestavkov za cepljenje |
| US6446109B2 (en) * | 1998-06-29 | 2002-09-03 | Sun Microsystems, Inc. | Application computing environment |
| US20080318889A1 (en) * | 1999-04-08 | 2008-12-25 | Antisoma Research Limited | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
| US7960540B2 (en) * | 1999-04-08 | 2011-06-14 | Advanced Cancer Therapeutics, Llc | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
| EP1181304B1 (de) | 1999-04-08 | 2007-10-10 | Antisoma Research Limited | Antiproliferative aktivität von g-reichen oligonukleotiden und verfahren um sie zur bindung an nukleotin zu verwenden |
| US20080318890A1 (en) * | 1999-04-08 | 2008-12-25 | Antisoma Research Limited | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
| US8114850B2 (en) * | 1999-04-08 | 2012-02-14 | Advanced Cancer Therapeutics, Llc | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
| IT1312568B1 (it) * | 1999-05-21 | 2002-04-22 | Genera Spa | Peptidi immunogenici e loro uso. |
| AU1013701A (en) | 1999-10-22 | 2001-05-08 | Aventis Pasteur Limited | Modified gp100 and uses thereof |
| JP3603138B2 (ja) * | 2000-02-18 | 2004-12-22 | 独立行政法人理化学研究所 | 細胞死抑制タンパク質 |
| AU2001258102B2 (en) | 2000-05-10 | 2007-03-01 | Aventis Pasteur Limited | Immunogenic polypeptides encoded by mage minigenes and uses thereof |
| JP2004501648A (ja) * | 2000-06-26 | 2004-01-22 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | チオレドキシンおよび目的のポリペプチドの間に融合するユビキチンを含む三重融合タンパク質 |
| JP4541645B2 (ja) | 2001-04-12 | 2010-09-08 | インペリアル・イノベイションズ・リミテッド | I型癌の診断および治療 |
| US7049413B2 (en) | 2001-05-18 | 2006-05-23 | Ludwig Institute For Cancer Research | MAGE-A3 peptides presented by HLA class II molecules |
| US20030148973A1 (en) * | 2001-05-23 | 2003-08-07 | Peter Emtage | MAGE-A1 peptides for treating or preventing cancer |
| US20030113919A1 (en) * | 2001-08-17 | 2003-06-19 | Aventis Pasteur, Ltd. | Immunogenic targets for melanoma |
| ATE517122T1 (de) | 2002-04-09 | 2011-08-15 | Sanofi Pasteur Ltd | Modifizierte cea-nukleinsäure und entsprechende expressionsvektoren |
| US20040223949A1 (en) * | 2002-10-22 | 2004-11-11 | Sunnybrook And Women's College Health Sciences Center Aventis Pasteur, Ltd. | Vaccines using high-dose cytokines |
| EP1670926B1 (de) * | 2003-10-08 | 2011-04-20 | Sanofi Pasteur Limited | Modifizierter cea/b7-vektor |
| DE10347710B4 (de) | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
| US20070154889A1 (en) * | 2004-06-25 | 2007-07-05 | Veridex, Llc | Methods and reagents for the detection of melanoma |
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| GB0700284D0 (en) * | 2007-01-08 | 2007-02-14 | Glaxosmithkline Biolog Sa | Combination therapy |
| SG187482A1 (en) | 2007-11-07 | 2013-02-28 | Celldex Therapeutics Inc | Antibodies that bind human dendritic and epithelial cell 205 (dec-205) |
| US20090131351A1 (en) * | 2007-11-16 | 2009-05-21 | Antisoma Research Limited | Methods, compositions, and kits for modulating tumor cell proliferation |
| CN102202687B (zh) | 2008-03-14 | 2015-07-29 | 赛诺菲巴斯德生物制剂有限责任公司 | 复制缺陷型黄病毒疫苗和疫苗载体 |
| EP3165540A1 (de) | 2010-04-13 | 2017-05-10 | Celldex Therapeutics, Inc. | Antikörper zur bindung von humanem cd27 und verwendungen davon |
| PL3892295T3 (pl) | 2011-05-24 | 2023-07-24 | BioNTech SE | Zindywidualizowane szczepionki przeciwnowotworowe |
| GB201120860D0 (en) | 2011-12-05 | 2012-01-18 | Cambridge Entpr Ltd | Cancer immunotherapy |
| WO2013143555A1 (en) | 2012-03-26 | 2013-10-03 | Biontech Ag | Rna formulation for immunotherapy |
| US10155031B2 (en) | 2012-11-28 | 2018-12-18 | Biontech Rna Pharmaceuticals Gmbh | Individualized vaccines for cancer |
| WO2014140938A2 (en) | 2013-03-14 | 2014-09-18 | Centre Hospitalier Universitaire Vaudois | Immunological methods |
| WO2014180490A1 (en) | 2013-05-10 | 2014-11-13 | Biontech Ag | Predicting immunogenicity of t cell epitopes |
| ES2901705T3 (es) | 2014-06-06 | 2022-03-23 | Bristol Myers Squibb Co | Anticuerpos contra el receptor del factor de necrosis tumoral inducido por glucocorticoides (GITR) y usos de los mismos |
| US10564165B2 (en) | 2014-09-10 | 2020-02-18 | Genentech, Inc. | Identification of immunogenic mutant peptides using genomic, transcriptomic and proteomic information |
| WO2016045732A1 (en) | 2014-09-25 | 2016-03-31 | Biontech Rna Pharmaceuticals Gmbh | Stable formulations of lipids and liposomes |
| WO2016094309A1 (en) | 2014-12-10 | 2016-06-16 | Myosotis | Inhibition of tnf signaling in cancer immunotherapy |
| WO2016128060A1 (en) | 2015-02-12 | 2016-08-18 | Biontech Ag | Predicting t cell epitopes useful for vaccination |
| EP3268037B1 (de) | 2015-03-09 | 2022-08-31 | Celldex Therapeutics, Inc. | Cd27 agonists |
| PL3303396T3 (pl) | 2015-05-29 | 2023-03-06 | Bristol-Myers Squibb Company | Przeciwciała przeciwko ox40 i ich zastosowanie |
| AU2016291817A1 (en) | 2015-07-16 | 2018-02-22 | Biolinerx Ltd. | Compositions and methods for treating cancer |
| WO2017059902A1 (en) | 2015-10-07 | 2017-04-13 | Biontech Rna Pharmaceuticals Gmbh | 3' utr sequences for stabilization of rna |
| GB201519340D0 (en) | 2015-11-02 | 2015-12-16 | Cambridge Entpr Ltd | Methods of T-lymphocyte expansion |
| GB201519481D0 (en) | 2015-11-04 | 2015-12-16 | Cancer Rec Tech Ltd | Immunomodulatory antibodies |
| AU2016356780A1 (en) | 2015-11-19 | 2018-06-28 | Bristol-Myers Squibb Company | Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof |
| EP3445783A2 (de) | 2016-04-18 | 2019-02-27 | Celldex Therapeutics, Inc. | Agonistische antikörper zur bindung von humanem cd40 und verwendungen davon |
| GB201616238D0 (en) | 2016-09-23 | 2016-11-09 | Adaptimmune Ltd | Modified T cells |
| WO2018127919A1 (en) | 2017-01-05 | 2018-07-12 | Kahr Medical Ltd. | A SIRP1 alpha-41BBL FUSION PROTEIN AND METHODS OF USE THEREOF |
| DK3565579T3 (da) | 2017-01-05 | 2023-09-04 | Kahr Medical Ltd | Pd1-41bbl-fusionsprotein og fremgangsmåder til anvendelse deraf |
| GB201700345D0 (en) | 2017-01-09 | 2017-02-22 | F-Star Beta Ltd | Conditional agonists of immune responses |
| IL250916A0 (en) | 2017-03-02 | 2017-06-29 | Geiger Benjamin | Methods for growing t cells in culture and their use |
| WO2018224166A1 (en) | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| US20210187023A1 (en) | 2017-06-27 | 2021-06-24 | The Trustees Of Princeton University | Compositions And Methods For Enhancing Immunotherapy |
| GB201713078D0 (en) | 2017-08-15 | 2017-09-27 | Adaptimmune Ltd | T Cell Modification |
| US12397036B2 (en) | 2018-01-26 | 2025-08-26 | Cambridge Enterprise Limited | Peptide exchange protein |
| WO2020012486A1 (en) | 2018-07-11 | 2020-01-16 | Kahr Medical Ltd. | SIRPalpha-4-1BBL VARIANT FUSION PROTEIN AND METHODS OF USE THEREOF |
| GB201811408D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | CD137 Binding Molecules |
| GB201811410D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | OX40 Binding molecules |
| GB201811404D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | Anti-CD137 Antibodies |
| US12329816B2 (en) | 2018-08-24 | 2025-06-17 | The Trustees Of Princeton University | Immunotherapy with metabolic enzyme expression |
| GB201820444D0 (en) | 2018-12-14 | 2019-01-30 | Adaptimmune Ltd | Marker for T cell expansion |
| CA3146248A1 (en) | 2019-07-11 | 2021-01-14 | Kahr Medical Ltd. | Heterodimers and methods of use thereof |
| GB201911954D0 (en) | 2019-08-20 | 2019-10-02 | Adaptimmune Ltd | Lentiviral transduction methods |
| US20230048719A1 (en) | 2019-12-31 | 2023-02-16 | Kahr Medical Ltd. | Methods of culturing t cells with a 4-1bbl fusion polypeptide and uses of same |
| WO2021137230A1 (en) | 2019-12-31 | 2021-07-08 | Kahr Medical Ltd. | Methods of culturing t cells and uses of same |
| CN111647066B (zh) * | 2020-07-01 | 2020-12-18 | 维肽瀛(上海)生物技术有限公司 | Wt1多肽肿瘤抑制剂 |
| IL276599A (en) | 2020-08-09 | 2022-03-01 | Yeda Res & Dev | T cell receptor unique to mage-a1 and its uses |
| KR20230126727A (ko) | 2020-12-30 | 2023-08-30 | 이뮤노믹 쎄라퓨틱스, 인크. | 항-hvem 항체 |
| GB202303250D0 (en) | 2023-03-06 | 2023-04-19 | King S College London | Method and compounds |
| WO2025155971A1 (en) | 2024-01-19 | 2025-07-24 | Immunomic Therapeutics, Inc | Anti-activin receptor 1c (alk-7) receptor antibodies |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61104788A (ja) * | 1984-10-26 | 1986-05-23 | Teijin Ltd | 核酸塩基配列 |
| US5342774A (en) * | 1991-05-23 | 1994-08-30 | Ludwig Institute For Cancer Research | Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1 |
| JPH05246889A (ja) * | 1992-03-05 | 1993-09-24 | Seitai Chiyousetsu Kenkyusho:Kk | 制癌方法および制癌剤 |
| US5405940A (en) * | 1992-08-31 | 1995-04-11 | Ludwig Institute For Cancer Research | Isolated nonapeptides derived from MAGE genes and uses thereof |
-
1993
- 1993-03-26 US US08/037,230 patent/US6235525B1/en not_active Expired - Lifetime
-
1994
- 1994-03-09 ZA ZA941644A patent/ZA941644B/xx unknown
- 1994-03-17 WO PCT/US1994/002877 patent/WO1994023031A1/en active IP Right Grant
- 1994-03-17 AU AU64475/94A patent/AU685790B2/en not_active Expired
- 1994-03-17 EP EP94912246A patent/EP0690915B1/de not_active Expired - Lifetime
- 1994-03-17 FI FI954536A patent/FI954536A7/fi unknown
- 1994-03-17 NZ NZ263693A patent/NZ263693A/en not_active IP Right Cessation
- 1994-03-17 KR KR1019950704143A patent/KR100288749B1/ko not_active Expired - Lifetime
- 1994-03-17 JP JP52211494A patent/JP3594307B2/ja not_active Expired - Lifetime
- 1994-03-17 DE DE69431834T patent/DE69431834T2/de not_active Expired - Lifetime
- 1994-03-17 CA CA002159098A patent/CA2159098C/en not_active Expired - Lifetime
- 1994-03-17 AT AT94912246T patent/ATE229072T1/de active
- 1994-03-26 CN CN94103919A patent/CN1110556C/zh not_active Expired - Lifetime
- 1994-07-18 TW TW083106555A patent/TW432111B/zh not_active IP Right Cessation
-
1995
- 1995-09-20 NO NO953699A patent/NO953699L/no not_active Application Discontinuation
-
1997
- 1997-11-12 US US08/967,727 patent/US6025474A/en not_active Expired - Lifetime
-
1999
- 1999-05-17 US US09/312,464 patent/US6599699B1/en not_active Expired - Lifetime
- 1999-09-23 US US09/404,026 patent/US6565857B1/en not_active Expired - Fee Related
-
2000
- 2000-05-26 US US09/579,197 patent/US6552180B1/en not_active Expired - Fee Related
- 2000-05-31 US US09/583,848 patent/US6946289B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU6447594A (en) | 1994-10-24 |
| NO953699D0 (no) | 1995-09-20 |
| FI954536A0 (fi) | 1995-09-25 |
| AU685790B2 (en) | 1998-01-29 |
| DE69431834T2 (de) | 2003-09-18 |
| EP0690915B1 (de) | 2002-12-04 |
| US6946289B1 (en) | 2005-09-20 |
| NZ263693A (en) | 1996-07-26 |
| EP0690915A1 (de) | 1996-01-10 |
| WO1994023031A1 (en) | 1994-10-13 |
| US6599699B1 (en) | 2003-07-29 |
| US6565857B1 (en) | 2003-05-20 |
| KR100288749B1 (ko) | 2001-05-02 |
| US6025474A (en) | 2000-02-15 |
| DE69431834D1 (de) | 2003-01-16 |
| FI954536L (fi) | 1995-09-25 |
| CA2159098C (en) | 2003-04-29 |
| JP3594307B2 (ja) | 2004-11-24 |
| EP0690915A4 (de) | 1997-11-12 |
| ZA941644B (en) | 1994-10-12 |
| CN1110556C (zh) | 2003-06-04 |
| CN1093751A (zh) | 1994-10-19 |
| JPH08508402A (ja) | 1996-09-10 |
| US6235525B1 (en) | 2001-05-22 |
| TW432111B (en) | 2001-05-01 |
| CA2159098A1 (en) | 1994-10-13 |
| FI954536A7 (fi) | 1995-09-25 |
| NO953699L (no) | 1995-11-20 |
| US6552180B1 (en) | 2003-04-22 |
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