ATE373095T1 - Mutierte muskelspezifische enhancer - Google Patents
Mutierte muskelspezifische enhancerInfo
- Publication number
- ATE373095T1 ATE373095T1 AT01984246T AT01984246T ATE373095T1 AT E373095 T1 ATE373095 T1 AT E373095T1 AT 01984246 T AT01984246 T AT 01984246T AT 01984246 T AT01984246 T AT 01984246T AT E373095 T1 ATE373095 T1 AT E373095T1
- Authority
- AT
- Austria
- Prior art keywords
- muscle
- specific enhancers
- expression systems
- present
- specific
- Prior art date
Links
- 239000003623 enhancer Substances 0.000 title abstract 2
- 230000014509 gene expression Effects 0.000 abstract 2
- 210000003205 muscle Anatomy 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- -1 genetic cassettes Substances 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1223—Phosphotransferases with a nitrogenous group as acceptor (2.7.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21843600P | 2000-07-14 | 2000-07-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE373095T1 true ATE373095T1 (de) | 2007-09-15 |
Family
ID=22815112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01984246T ATE373095T1 (de) | 2000-07-14 | 2001-07-13 | Mutierte muskelspezifische enhancer |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20110097761A1 (de) |
| EP (1) | EP1303617B1 (de) |
| AT (1) | ATE373095T1 (de) |
| AU (1) | AU2294102A (de) |
| DE (1) | DE60130465T2 (de) |
| WO (1) | WO2002006495A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9353164B2 (en) * | 2009-10-29 | 2016-05-31 | Vib Vzw | Cardiac-specific nucleic acid regulatory elements and methods and use thereof |
| CN104031919B (zh) * | 2014-03-24 | 2017-04-19 | 内蒙古大学 | 一种能够在哺乳动物肌肉组织中特异启动基因表达的启动子序列及其应用 |
| MA45477A (fr) | 2016-04-15 | 2019-02-20 | Res Inst Nationwide Childrens Hospital | Administration à vecteurs de virus adéno-associé de microarn-29 et micro-dystrophine pour traiter la dystrophie musculaire |
| CA2971303A1 (en) | 2016-06-21 | 2017-12-21 | Bamboo Therapeutics, Inc. | Optimized mini-dystrophin genes and expression cassettes and their use |
| MA47800A (fr) | 2017-03-17 | 2020-01-22 | Univ Newcastle | Délivrance par vecteur viral adéno-associé d'un fragment de micro-dystrophine pour traiter la dystrophie musculaire |
| WO2019078916A1 (en) | 2017-10-18 | 2019-04-25 | Research Institute At Nationwide Children's Hospital | ADENO-ASSOCIATED VIRUS VECTOR ADMINISTRATION OF MUSCLE-SPECIFIC MICRO-DYSTROPHINE TO TREAT MUSCLE DYSTROPHY |
| EP3847261A1 (de) * | 2018-09-05 | 2021-07-14 | Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft | Verfahren zum engineering von synthetischer cis-regulierender dna |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994132A (en) * | 1996-10-23 | 1999-11-30 | University Of Michigan | Adenovirus vectors |
-
2001
- 2001-07-13 WO PCT/US2001/022092 patent/WO2002006495A2/en active IP Right Grant
- 2001-07-13 DE DE60130465T patent/DE60130465T2/de not_active Expired - Lifetime
- 2001-07-13 AT AT01984246T patent/ATE373095T1/de not_active IP Right Cessation
- 2001-07-13 AU AU2294102A patent/AU2294102A/xx active Pending
- 2001-07-13 EP EP01984246A patent/EP1303617B1/de not_active Expired - Lifetime
- 2001-07-13 US US10/332,516 patent/US20110097761A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1303617A2 (de) | 2003-04-23 |
| HK1055444A1 (en) | 2004-01-09 |
| EP1303617B1 (de) | 2007-09-12 |
| DE60130465D1 (de) | 2007-10-25 |
| US20110097761A1 (en) | 2011-04-28 |
| DE60130465T2 (de) | 2008-06-12 |
| WO2002006495A3 (en) | 2002-07-04 |
| AU2294102A (en) | 2002-01-30 |
| WO2002006495A2 (en) | 2002-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |