ATE335729T1 - 3h-chinazoline -4-on derivaten - Google Patents

3h-chinazoline -4-on derivaten

Info

Publication number: ATE335729T1
Authority: AT; Austria
Prior art keywords: chinazoline; derivatives
Prior art date: 2002-12-13

Application number

AT03789170T

Other languages

English (en)

Inventor

Sarmiento Rosa Maria Rodriguez

Andrew William Thomas

Rene Wyler

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-13

Filing date

2003-12-08

Publication date

2006-09-15

2003-12-08 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2006-09-15 Application granted granted Critical

2006-09-15 Publication of ATE335729T1 publication Critical patent/ATE335729T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT03789170T 2002-12-13 2003-12-08 3h-chinazoline -4-on derivaten ATE335729T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02027700		2002-12-13

Publications (1)

Publication Number	Publication Date
ATE335729T1 true ATE335729T1 (de)	2006-09-15

Family

ID=32524001

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03789170T ATE335729T1 (de)	2002-12-13	2003-12-08	3h-chinazoline -4-on derivaten

Country Status (23)

Country	Link
US (1)	US7087612B2 (de)
EP (1)	EP1572666B1 (de)
JP (1)	JP4384053B2 (de)
KR (1)	KR100707532B1 (de)
CN (1)	CN100418954C (de)
AR (1)	AR042362A1 (de)
AT (1)	ATE335729T1 (de)
AU (1)	AU2003293798B8 (de)
BR (1)	BR0317282A (de)
CA (1)	CA2509633A1 (de)
CL (1)	CL2003002565A1 (de)
DE (1)	DE60307512T2 (de)
ES (1)	ES2270154T3 (de)
GT (1)	GT200300284A (de)
MX (1)	MXPA05006124A (de)
MY (1)	MY141743A (de)
PA (1)	PA8591901A1 (de)
PE (1)	PE20040911A1 (de)
PL (1)	PL377474A1 (de)
RU (1)	RU2340604C2 (de)
TW (1)	TW200424180A (de)
UY (1)	UY28120A1 (de)
WO (1)	WO2004054985A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1838296B1 (de)	2004-10-20	2012-08-08	Resverlogix Corp.	Flavonoide und isoflavonoide zur vorbeugung und behandlung cardiovasculärer erkrankungen
EP2281556A1 (de)	2005-02-25	2011-02-09	F. Hoffmann-La Roche AG	Tablette mit verbesserter Arzneimittelsubstanzdispersibilität
WO2007016525A2 (en)	2005-07-29	2007-02-08	Resverlogix Corp.	Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
GB0525068D0 (en) *	2005-12-08	2006-01-18	Novartis Ag	Organic compounds
JP4876690B2 (ja) *	2006-04-21	2012-02-15	三菱瓦斯化学株式会社	キナゾリン−４−オン誘導体の製造法
EP2123627B1 (de) *	2007-01-19	2013-11-20	Ube Industries, Ltd.	Verfahren zur herstellung eines aromatischen amins mit einer aralkyloxy- oder heteroaralkyloxygruppe
CA2676984C (en)	2007-02-01	2015-03-17	Resverlogix Corp.	Compounds for the prevention and treatment of cardiovascular diseases
WO2009158404A1 (en)	2008-06-26	2009-12-30	Resverlogix Corp.	Methods of preparing quinazolinone derivatives
CA2747417C (en)	2009-01-08	2017-01-03	Resverlogix Corp.	Compounds for the prevention and treatment of cardiovascular disease
JP5795304B2 (ja)	2009-03-18	2015-10-14	レスバーロジックスコーポレイション	新規抗炎症剤
EP3431086B1 (de)	2009-04-22	2020-06-17	Resverlogix Corp.	Neuartige entzündungshemmende mittel
RS58911B1 (sr)	2011-11-01	2019-08-30	Resverlogix Corp	Oralne formulacije sa trenutnim otpuštanjem za supstituisane hinazolinone
WO2014080290A2 (en)	2012-11-21	2014-05-30	Rvx Therapeutics Inc.	Cyclic amines as bromodomain inhibitors
WO2014080291A2 (en)	2012-11-21	2014-05-30	Rvx Therapeutics Inc.	Biaryl derivatives as bromodomain inhibitors
US9271978B2 (en)	2012-12-21	2016-03-01	Zenith Epigenetics Corp.	Heterocyclic compounds as bromodomain inhibitors
CA2977308A1 (en)	2015-03-13	2016-09-22	Resverlogix Corp.	Compositions and therapeutic methods for the treatment of complement-associated diseases
CN106146410B (zh) *	2015-04-03	2018-10-12	中南大学	6-氨基-4(3h)-喹唑啉酮衍生物及其合成方法和用途
CN108191667B (zh) *	2018-01-04	2021-03-26	利尔化学股份有限公司	2-硝基-4-三氟甲基苯甲酸甲酯的制备方法
CN109553534A (zh) *	2018-11-27	2019-04-02	常州大学	一种2-硝基-4-甲氧基苯甲酸的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6136273A (ja) *	1984-07-26	1986-02-20	Mitsubishi Yuka Yakuhin Kk	２−フエニルアルキル−４（３ｈ）−キナゾリノン誘導体
HUP9801828A3 (en) *	1995-03-14	2001-02-28	Novartis Ag	Benzoic acid, quinoline and quinazoline derivatives, pharmaceutical compositions containing them and process for producing them
IL117659A (en) *	1995-04-13	2000-12-06	Dainippon Pharmaceutical Co	Substituted 2-phenyl pyrimidino amino acetamide derivative process for preparing the same and a pharmaceutical composition containing same
US5679715A (en)	1995-06-07	1997-10-21	Harris; Richard Y.	Method for treating multiple sclerosis
US5783577A (en) *	1995-09-15	1998-07-21	Trega Biosciences, Inc.	Synthesis of quinazolinone libraries and derivatives thereof
CA2244253C (en)	1996-03-15	2002-11-12	Somerset Pharmaceuticals, Inc.	Method for preventing and treating peripheral neuropathy by administering selegiline
EP1005470B1 (de) *	1997-08-22	2007-08-01	AstraZeneca AB	Oxindolylchinazolinderivate als angiogenesehemmer
US6890930B1 (en) *	1999-09-28	2005-05-10	3-Dimensional Pharmaceuticals, Inc.	Quinazolinones
WO2001034172A2 (en)	1999-11-05	2001-05-17	Vela Pharmaceuticals Inc.	Methods and compositions for treating reward deficiency syndrome

2003
- 2003-12-08 EP EP03789170A patent/EP1572666B1/de not_active Expired - Lifetime
- 2003-12-08 PL PL377474A patent/PL377474A1/pl not_active Application Discontinuation
- 2003-12-08 DE DE60307512T patent/DE60307512T2/de not_active Expired - Lifetime
- 2003-12-08 CN CNB2003801052982A patent/CN100418954C/zh not_active Expired - Fee Related
- 2003-12-08 RU RU2005121908/04A patent/RU2340604C2/ru not_active IP Right Cessation
- 2003-12-08 AT AT03789170T patent/ATE335729T1/de not_active IP Right Cessation
- 2003-12-08 BR BR0317282-1A patent/BR0317282A/pt not_active IP Right Cessation
- 2003-12-08 KR KR1020057010696A patent/KR100707532B1/ko not_active Expired - Fee Related
- 2003-12-08 WO PCT/EP2003/013888 patent/WO2004054985A1/en active IP Right Grant
- 2003-12-08 JP JP2004559781A patent/JP4384053B2/ja not_active Expired - Lifetime
- 2003-12-08 CA CA002509633A patent/CA2509633A1/en not_active Abandoned
- 2003-12-08 ES ES03789170T patent/ES2270154T3/es not_active Expired - Lifetime
- 2003-12-08 AU AU2003293798A patent/AU2003293798B8/en not_active Ceased
- 2003-12-08 MX MXPA05006124A patent/MXPA05006124A/es active IP Right Grant
- 2003-12-09 TW TW092134699A patent/TW200424180A/zh unknown
- 2003-12-10 CL CL200302565A patent/CL2003002565A1/es unknown
- 2003-12-10 PA PA20038591901A patent/PA8591901A1/es unknown
- 2003-12-10 PE PE2003001256A patent/PE20040911A1/es not_active Application Discontinuation
- 2003-12-11 GT GT200300284A patent/GT200300284A/es unknown
- 2003-12-11 UY UY28120A patent/UY28120A1/es not_active Application Discontinuation
- 2003-12-11 AR ARP030104562A patent/AR042362A1/es unknown
- 2003-12-12 MY MYPI20034764A patent/MY141743A/en unknown
- 2003-12-13 US US10/734,949 patent/US7087612B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP2006513177A (ja)	2006-04-20
MY141743A (en)	2010-06-30
GT200300284A (es)	2004-07-14
KR20050085587A (ko)	2005-08-29
PE20040911A1 (es)	2004-12-11
PA8591901A1 (es)	2004-11-26
CN1720237A (zh)	2006-01-11
MXPA05006124A (es)	2005-08-16
RU2005121908A (ru)	2006-01-27
EP1572666A1 (de)	2005-09-14
TW200424180A (en)	2004-11-16
CN100418954C (zh)	2008-09-17
KR100707532B1 (ko)	2007-04-12
EP1572666B1 (de)	2006-08-09
JP4384053B2 (ja)	2009-12-16
WO2004054985A1 (en)	2004-07-01
UY28120A1 (es)	2004-06-30
AU2003293798A1 (en)	2004-07-09
CA2509633A1 (en)	2004-07-01
PL377474A1 (pl)	2006-02-06
DE60307512D1 (de)	2006-09-21
AR042362A1 (es)	2005-06-15
US20040142951A1 (en)	2004-07-22
AU2003293798B2 (en)	2009-01-15
RU2340604C2 (ru)	2008-12-10
ES2270154T3 (es)	2007-04-01
US7087612B2 (en)	2006-08-08
AU2003293798B8 (en)	2009-02-12
CL2003002565A1 (es)	2005-01-07
BR0317282A (pt)	2005-11-08
DE60307512T2 (de)	2007-02-08

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DE50305973D1 (de)	2007-01-25	Auffangwanne
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ATE395327T1 (de)	2008-05-15	Amidoacetonitrilderivate

Legal Events

Date	Code	Title	Description
2007-06-15	UEP	Publication of translation of european patent specification	Ref document number: 1572666 Country of ref document: EP
2011-09-15	REN	Ceased due to non-payment of the annual fee

Date

Code

Title

Description

2007-06-15

UEP

Publication of translation of european patent specification

Ref document number: 1572666

Country of ref document: EP

2011-09-15

REN

Ceased due to non-payment of the annual fee