ATE448794T1 - Aluminiumadjuvans und histidin enthaltende impstoffe - Google Patents
Aluminiumadjuvans und histidin enthaltende impstoffeInfo
- Publication number
- ATE448794T1 ATE448794T1 AT02767756T AT02767756T ATE448794T1 AT E448794 T1 ATE448794 T1 AT E448794T1 AT 02767756 T AT02767756 T AT 02767756T AT 02767756 T AT02767756 T AT 02767756T AT E448794 T1 ATE448794 T1 AT E448794T1
- Authority
- AT
- Austria
- Prior art keywords
- histidine
- adjuvans
- containing aluminum
- vaccines containing
- stability
- Prior art date
Links
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 239000002671 adjuvant Substances 0.000 title abstract 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 title 1
- 229910052782 aluminium Inorganic materials 0.000 title 1
- 159000000013 aluminium salts Chemical class 0.000 abstract 2
- 229910000329 aluminium sulfate Inorganic materials 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 238000001179 sorption measurement Methods 0.000 abstract 2
- 241000588650 Neisseria meningitidis Species 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Lubricants (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0118249.2A GB0118249D0 (en) | 2001-07-26 | 2001-07-26 | Histidine vaccines |
| PCT/IB2002/003191 WO2003007985A2 (en) | 2001-06-20 | 2002-06-20 | Capsular polysaccharide solubilisation and combination vaccines |
| PCT/IB2002/003495 WO2003009869A1 (en) | 2001-07-26 | 2002-07-26 | Vaccines comprising aluminium adjuvants and histidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE448794T1 true ATE448794T1 (de) | 2009-12-15 |
Family
ID=9919246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02767756T ATE448794T1 (de) | 2001-07-26 | 2002-07-26 | Aluminiumadjuvans und histidin enthaltende impstoffe |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US7348006B2 (de) |
| EP (3) | EP2255827A1 (de) |
| JP (2) | JP4509554B2 (de) |
| AT (1) | ATE448794T1 (de) |
| BR (1) | BR0211437A (de) |
| CY (1) | CY1109791T1 (de) |
| DE (1) | DE60234448D1 (de) |
| DK (1) | DK1409013T3 (de) |
| ES (1) | ES2334495T3 (de) |
| GB (1) | GB0118249D0 (de) |
| MX (1) | MXPA04000753A (de) |
| PT (1) | PT1409013E (de) |
| RU (1) | RU2432173C2 (de) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030072774A1 (en) * | 1994-06-10 | 2003-04-17 | Diane M. Gajewczyk | Proteinaceous adjuvants |
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| JP4812942B2 (ja) * | 1999-02-26 | 2011-11-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | CGモチーフを含むオリゴヌクレオチドを用いるNeisseria抗原殺菌活性の増強 |
| BR0010130A (pt) | 1999-04-30 | 2002-06-04 | Chiron Spa | Antìgenos de neisseria conservados |
| AU783894B2 (en) | 1999-05-19 | 2005-12-22 | Novartis Vaccines And Diagnostics S.R.L. | Combination neisserial compositions |
| MXPA02004283A (es) | 1999-10-29 | 2002-10-17 | Chiron Spa | Peptidos antigenicos neisseriales. |
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| CN100473663C (zh) | 2000-02-28 | 2009-04-01 | 启龙股份公司 | 奈瑟球菌蛋白质的异源表达 |
| EP2189473A3 (de) * | 2000-10-27 | 2010-08-11 | Novartis Vaccines and Diagnostics S.r.l. | Nukleinsäure und Proteine von Gruppen A und B Streptokokken |
| GB0108079D0 (en) * | 2001-03-30 | 2001-05-23 | Microbial Technics Ltd | Protein |
| GB0118249D0 (en) * | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| ES2615362T3 (es) | 2001-07-27 | 2017-06-06 | Glaxosmithkline Biologicals Sa | Adhesinas de meningococos |
| GB0210128D0 (en) * | 2002-05-02 | 2002-06-12 | Chiron Spa | Nucleic acids and proteins from streptococcus groups A & B |
| US20060057160A1 (en) * | 2002-08-02 | 2006-03-16 | Ralph Biemans | Vaccine composition |
| EP1597348A4 (de) * | 2002-08-26 | 2010-03-31 | Novartis Vaccines & Diagnostic | Konservierte und spezifische streptokokkengenome |
| GB0220194D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| PT2351579T (pt) * | 2002-10-11 | 2016-12-22 | Novartis Vaccines And Diagnostics S R L | Vacinas polipeptídicas para proteção ampla contra linhagens meningocócicas hipervirulentas |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| EP1648500B1 (de) | 2003-07-31 | 2014-07-09 | Novartis Vaccines and Diagnostics, Inc. | Immunogene zusammensetzungen für streptococcus pyogenes |
| US8945589B2 (en) * | 2003-09-15 | 2015-02-03 | Novartis Vaccines And Diagnostics, Srl | Immunogenic compositions for Streptococcus agalactiae |
| GB0408977D0 (en) * | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| WO2006078318A2 (en) * | 2004-07-29 | 2006-07-27 | Novartis Vaccines And Diagnostics Inc. | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
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| AP2436A (en) | 2005-06-27 | 2012-08-31 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| CA2632434A1 (en) * | 2005-12-06 | 2007-06-14 | Universita Degli Studi Di Padova | Methods and compositions relating to adhesins as adjuvants |
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| US20100015168A1 (en) * | 2006-06-09 | 2010-01-21 | Novartis Ag | Immunogenic compositions for streptococcus agalactiae |
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| ES2561483T3 (es) | 2007-09-12 | 2016-02-26 | Glaxosmithkline Biologicals Sa | Antígenos mutantes de GAS57 y anticuerpos de GAS57 |
| CN104740624B (zh) | 2007-09-18 | 2018-04-24 | 武田疫苗股份有限公司 | 赋予针对诺如病毒的保护性免疫应答的疫苗 |
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| RU2475496C2 (ru) * | 2008-02-21 | 2013-02-20 | Новартис Аг | МЕНИНГОКОККОВЫЕ ПОЛИПЕПТИДЫ fHBP |
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| EP2411048B1 (de) * | 2009-03-24 | 2020-05-06 | GlaxoSmithKline Biologicals SA | Adjuvantierendes meningokokken-faktor-h-bindungsprotein |
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-
2001
- 2001-07-26 GB GBGB0118249.2A patent/GB0118249D0/en not_active Ceased
-
2002
- 2002-07-26 PT PT02767756T patent/PT1409013E/pt unknown
- 2002-07-26 EP EP10179756A patent/EP2255827A1/de not_active Withdrawn
- 2002-07-26 JP JP2003515261A patent/JP4509554B2/ja not_active Expired - Lifetime
- 2002-07-26 EP EP10179753A patent/EP2266605A1/de not_active Withdrawn
- 2002-07-26 DE DE60234448T patent/DE60234448D1/de not_active Expired - Lifetime
- 2002-07-26 BR BR0211437-2A patent/BR0211437A/pt not_active Application Discontinuation
- 2002-07-26 DK DK02767756.6T patent/DK1409013T3/da active
- 2002-07-26 US US10/484,702 patent/US7348006B2/en not_active Expired - Lifetime
- 2002-07-26 ES ES02767756T patent/ES2334495T3/es not_active Expired - Lifetime
- 2002-07-26 AT AT02767756T patent/ATE448794T1/de active
- 2002-07-26 EP EP09014171A patent/EP2168597A1/de not_active Withdrawn
- 2002-07-26 MX MXPA04000753A patent/MXPA04000753A/es active IP Right Grant
-
2007
- 2007-10-29 RU RU2007139924/15A patent/RU2432173C2/ru active
-
2008
- 2008-01-03 US US11/968,920 patent/US7754218B2/en not_active Expired - Lifetime
-
2009
- 2009-05-11 JP JP2009115050A patent/JP2009173681A/ja active Pending
-
2010
- 2010-02-05 CY CY20101100116T patent/CY1109791T1/el unknown
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- 2012-02-02 US US13/365,202 patent/USRE45587E1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB0118249D0 (en) | 2001-09-19 |
| CY1109791T1 (el) | 2014-09-10 |
| US20050158334A1 (en) | 2005-07-21 |
| EP2168597A1 (de) | 2010-03-31 |
| RU2007139924A (ru) | 2009-05-10 |
| EP2255827A1 (de) | 2010-12-01 |
| RU2432173C2 (ru) | 2011-10-27 |
| DE60234448D1 (de) | 2009-12-31 |
| USRE45587E1 (en) | 2015-06-30 |
| US7348006B2 (en) | 2008-03-25 |
| BR0211437A (pt) | 2004-07-13 |
| US20080160045A1 (en) | 2008-07-03 |
| ES2334495T3 (es) | 2010-03-11 |
| JP2009173681A (ja) | 2009-08-06 |
| JP2004538291A (ja) | 2004-12-24 |
| US7754218B2 (en) | 2010-07-13 |
| DK1409013T3 (da) | 2010-01-18 |
| PT1409013E (pt) | 2010-02-26 |
| MXPA04000753A (es) | 2005-02-17 |
| EP2266605A1 (de) | 2010-12-29 |
| JP4509554B2 (ja) | 2010-07-21 |
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