ATE476960T1 - System zur kontrollierten freisetzung eines bioaktiven wirkstoffs im hinteren bereich des auges - Google Patents
System zur kontrollierten freisetzung eines bioaktiven wirkstoffs im hinteren bereich des augesInfo
- Publication number
- ATE476960T1 ATE476960T1 AT05025475T AT05025475T ATE476960T1 AT E476960 T1 ATE476960 T1 AT E476960T1 AT 05025475 T AT05025475 T AT 05025475T AT 05025475 T AT05025475 T AT 05025475T AT E476960 T1 ATE476960 T1 AT E476960T1
- Authority
- AT
- Austria
- Prior art keywords
- eye
- polymer
- body member
- extension
- bioactive agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00353—Bone cement, e.g. polymethylmethacrylate or PMMA
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Prostheses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46741903P | 2003-05-02 | 2003-05-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE476960T1 true ATE476960T1 (de) | 2010-08-15 |
Family
ID=33435072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05025475T ATE476960T1 (de) | 2003-05-02 | 2004-04-29 | System zur kontrollierten freisetzung eines bioaktiven wirkstoffs im hinteren bereich des auges |
Country Status (8)
| Country | Link |
|---|---|
| US (7) | US8021680B2 (de) |
| EP (1) | EP1633320A2 (de) |
| JP (3) | JP4824549B2 (de) |
| AT (1) | ATE476960T1 (de) |
| AU (1) | AU2004237774B2 (de) |
| CA (1) | CA2524271C (de) |
| DE (1) | DE602004028638D1 (de) |
| WO (1) | WO2004098565A2 (de) |
Families Citing this family (240)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7713297B2 (en) * | 1998-04-11 | 2010-05-11 | Boston Scientific Scimed, Inc. | Drug-releasing stent with ceramic-containing layer |
| EP1174157B1 (de) | 1998-04-27 | 2005-06-29 | Surmodics Inc. | Bioaktive Wirkstoffe freisetzende Beschichtungen |
| US20020188037A1 (en) * | 1999-04-15 | 2002-12-12 | Chudzik Stephen J. | Method and system for providing bioactive agent release coating |
| US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
| US7727221B2 (en) | 2001-06-27 | 2010-06-01 | Cardiac Pacemakers Inc. | Method and device for electrochemical formation of therapeutic species in vivo |
| US7097850B2 (en) * | 2002-06-18 | 2006-08-29 | Surmodics, Inc. | Bioactive agent release coating and controlled humidity method |
| US20030232087A1 (en) * | 2002-06-18 | 2003-12-18 | Lawin Laurie R. | Bioactive agent release coating with aromatic poly(meth)acrylates |
| ATE476960T1 (de) * | 2003-05-02 | 2010-08-15 | Surmodics Inc | System zur kontrollierten freisetzung eines bioaktiven wirkstoffs im hinteren bereich des auges |
| US8246974B2 (en) * | 2003-05-02 | 2012-08-21 | Surmodics, Inc. | Medical devices and methods for producing the same |
| AU2004266484B2 (en) * | 2003-08-19 | 2011-04-14 | Bayer Materialscience Ag | Polymeric drug release system for medical devices |
| ATE416223T1 (de) * | 2003-08-29 | 2008-12-15 | Mayo Foundation | Hydrogel-porenbildner zur herstellung von biologisch abbaubaren gerüsten |
| EP1663469A4 (de) * | 2003-09-05 | 2009-01-07 | Univ Massachusetts | Kapseln aus amphiphilem polymer und zugehörige verfahren zum grenzflächenfügen |
| US7976520B2 (en) * | 2004-01-12 | 2011-07-12 | Nulens Ltd. | Eye wall anchored fixtures |
| US20050222613A1 (en) * | 2004-02-05 | 2005-10-06 | Edwin Ryan | Wound closure device and method for vitrectomy |
| US20060083772A1 (en) * | 2004-04-06 | 2006-04-20 | Dewitt David M | Coating compositions for bioactive agents |
| WO2005099787A1 (en) * | 2004-04-06 | 2005-10-27 | Surmodics, Inc. | Coating compositions for bioactive agents |
| US20050232972A1 (en) * | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
| US7758892B1 (en) * | 2004-05-20 | 2010-07-20 | Boston Scientific Scimed, Inc. | Medical devices having multiple layers |
| WO2006002366A2 (en) * | 2004-06-24 | 2006-01-05 | Surmodics, Inc. | Biodegradable ocular devices, methods and systems |
| EP1765454B1 (de) | 2004-07-02 | 2016-04-13 | Mati Therapeutics Inc. | Behandlungsmittelabgabevorrichtung für das auge |
| WO2006014484A2 (en) | 2004-07-02 | 2006-02-09 | Surmodics, Inc. | Methods and devices for the treatment of ocular conditions |
| WO2006078320A2 (en) | 2004-08-04 | 2006-07-27 | Brookwood Pharmaceuticals, Inc. | Methods for manufacturing delivery devices and devices thereof |
| WO2006023130A2 (en) * | 2004-08-12 | 2006-03-02 | Surmodics, Inc. | Biodegradable controlled release bioactive agent delivery device |
| AU2005304567B2 (en) | 2004-11-12 | 2011-10-27 | Mayo Foundation For Medical Education And Research | Photocrosslinkable poly(caprolactone fumarate) |
| WO2006063021A2 (en) * | 2004-12-07 | 2006-06-15 | Surmodics, Inc. | Coatngs with crystallized active agents (s) |
| US20060127443A1 (en) * | 2004-12-09 | 2006-06-15 | Helmus Michael N | Medical devices having vapor deposited nanoporous coatings for controlled therapeutic agent delivery |
| US20060147491A1 (en) * | 2005-01-05 | 2006-07-06 | Dewitt David M | Biodegradable coating compositions including multiple layers |
| US20060198868A1 (en) * | 2005-01-05 | 2006-09-07 | Dewitt David M | Biodegradable coating compositions comprising blends |
| US8878146B2 (en) * | 2005-03-07 | 2014-11-04 | The Regents Of The University Of California | Medical implants |
| JP2008535563A (ja) * | 2005-04-06 | 2008-09-04 | サーモディクス,インコーポレイティド | 生物活性剤のためのコーティング組成物 |
| US20060228390A1 (en) * | 2005-04-07 | 2006-10-12 | Williams David F | Intravitreal implant |
| US8003124B2 (en) * | 2005-04-08 | 2011-08-23 | Surmodics, Inc. | Sustained release implants and methods for subretinal delivery of bioactive agents to treat or prevent retinal disease |
| CA2606396A1 (en) * | 2005-04-29 | 2006-11-09 | Mayo Foundation For Medical Education And Research | Hydrophilic/hydrophobic polymer networks based on poly(caprolactone fumarate), poly(ethylene glycol fumarate), and copolymers thereof |
| CN101198301A (zh) * | 2005-05-18 | 2008-06-11 | 苏尔莫迪克斯公司 | 用于非线性医用装置的插入器械 |
| US20070038176A1 (en) * | 2005-07-05 | 2007-02-15 | Jan Weber | Medical devices with machined layers for controlled communications with underlying regions |
| US7833463B1 (en) * | 2005-07-18 | 2010-11-16 | Advanced Neuromodulation Systems, Inc. | System and method for removing an organic film from a selected portion of an implantable medical device using an infrared laser |
| US8663673B2 (en) | 2005-07-29 | 2014-03-04 | Surmodics, Inc. | Devices, articles, coatings, and methods for controlled active agent release or hemocompatibility |
| ES2441608T3 (es) * | 2005-08-18 | 2014-02-05 | Zimmer Gmbh | Artículos de polietileno de peso molecular ultra-alto y métodos para formar artículos de polietileno de peso molecular ulra-alto |
| WO2007028005A2 (en) * | 2005-09-01 | 2007-03-08 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to vascular endothelial growth factor receptor-2 modulators |
| US20070212397A1 (en) * | 2005-09-15 | 2007-09-13 | Roth Daniel B | Pharmaceutical delivery device and method for providing ocular treatment |
| ATE454908T1 (de) * | 2005-09-21 | 2010-01-15 | Surmodics Inc | In situ okklusionszusammensetzungen mit natürlichen biologisch abbaubaren polysacchariden |
| ATE540705T1 (de) | 2005-09-21 | 2012-01-15 | Surmodics Inc | Überzüge und artikel mit natürlichen biologisch abbaubaren polysacchariden |
| WO2007059144A1 (en) * | 2005-11-15 | 2007-05-24 | Surmodics, Inc. | Ultrasonic nozzles for applying two-component coatings |
| US8840660B2 (en) * | 2006-01-05 | 2014-09-23 | Boston Scientific Scimed, Inc. | Bioerodible endoprostheses and methods of making the same |
| JP5819579B2 (ja) * | 2006-01-13 | 2015-11-24 | サーモディクス,インコーポレイティド | 薬物送達のためのマトリックスを含む微粒子 |
| CA2637602C (en) * | 2006-01-17 | 2014-09-16 | Forsight Labs, Llc | Drug delivery treatment device |
| EP3632385B1 (de) | 2006-01-17 | 2024-08-07 | Alcon Inc. | Glaukombehandlungsvorrichtung |
| US8089029B2 (en) * | 2006-02-01 | 2012-01-03 | Boston Scientific Scimed, Inc. | Bioabsorbable metal medical device and method of manufacture |
| EP2004252A2 (de) * | 2006-03-15 | 2008-12-24 | SurModics, Inc. | Hydrophobe derivate natürlicher biologisch abbaubarer polysaccharide und ihre verwendung |
| US20070224244A1 (en) * | 2006-03-22 | 2007-09-27 | Jan Weber | Corrosion resistant coatings for biodegradable metallic implants |
| US20070224235A1 (en) * | 2006-03-24 | 2007-09-27 | Barron Tenney | Medical devices having nanoporous coatings for controlled therapeutic agent delivery |
| US8187620B2 (en) * | 2006-03-27 | 2012-05-29 | Boston Scientific Scimed, Inc. | Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents |
| BRPI0709663A2 (pt) | 2006-03-31 | 2011-07-26 | Qlt Plug Delivery Inc | mÉtodos de liberaÇço de drogas, estruturas e composiÇÕes para um sistema nasolacrimal |
| US8048150B2 (en) * | 2006-04-12 | 2011-11-01 | Boston Scientific Scimed, Inc. | Endoprosthesis having a fiber meshwork disposed thereon |
| US20070264303A1 (en) * | 2006-05-12 | 2007-11-15 | Liliana Atanasoska | Coating for medical devices comprising an inorganic or ceramic oxide and a therapeutic agent |
| US9474645B2 (en) * | 2006-06-21 | 2016-10-25 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
| US8815275B2 (en) | 2006-06-28 | 2014-08-26 | Boston Scientific Scimed, Inc. | Coatings for medical devices comprising a therapeutic agent and a metallic material |
| US8968782B2 (en) * | 2006-06-28 | 2015-03-03 | Surmodics, Inc. | Combination degradable and non-degradable matrices for active agent delivery |
| JP2009542671A (ja) * | 2006-06-28 | 2009-12-03 | サーモディクス,インコーポレイティド | 微粒子を含む活性剤溶出マトリックス |
| WO2008002778A2 (en) * | 2006-06-29 | 2008-01-03 | Boston Scientific Limited | Medical devices with selective coating |
| US8052743B2 (en) | 2006-08-02 | 2011-11-08 | Boston Scientific Scimed, Inc. | Endoprosthesis with three-dimensional disintegration control |
| US20080171087A1 (en) * | 2006-08-16 | 2008-07-17 | Chappa Ralph A | Methods and materials for increasing the adhesion of elution control matrices to substrates |
| JP2010503469A (ja) | 2006-09-14 | 2010-02-04 | ボストン サイエンティフィック リミテッド | 薬物溶出性皮膜を有する医療デバイス |
| JP2010503485A (ja) * | 2006-09-15 | 2010-02-04 | ボストン サイエンティフィック リミテッド | 医療用デバイスおよび同デバイスの製造方法 |
| US8808726B2 (en) * | 2006-09-15 | 2014-08-19 | Boston Scientific Scimed. Inc. | Bioerodible endoprostheses and methods of making the same |
| US8128689B2 (en) | 2006-09-15 | 2012-03-06 | Boston Scientific Scimed, Inc. | Bioerodible endoprosthesis with biostable inorganic layers |
| US8057534B2 (en) | 2006-09-15 | 2011-11-15 | Boston Scientific Scimed, Inc. | Bioerodible endoprostheses and methods of making the same |
| CA2663762A1 (en) * | 2006-09-18 | 2008-03-27 | Boston Scientific Limited | Endoprostheses |
| JP2010503463A (ja) * | 2006-09-18 | 2010-02-04 | ボストン サイエンティフィック リミテッド | 医療機器の生分解の制御 |
| WO2008039749A2 (en) * | 2006-09-25 | 2008-04-03 | Surmodics, Inc. | Multi-layered coatings and methods for controlling elution of active agents |
| WO2008088593A2 (en) * | 2006-09-27 | 2008-07-24 | Surmodics, Inc. | Additives and methods for enhancing active agent elution kinetics |
| EP2068828A2 (de) * | 2006-09-29 | 2009-06-17 | SurModics, Inc. | Biologisch abbaubare augenimplantate und verfahren zur behandlung von augenleiden |
| WO2008045184A1 (en) * | 2006-10-05 | 2008-04-17 | Boston Scientific Limited | Polymer-free coatings for medical devices formed by plasma electrolytic deposition |
| US7981150B2 (en) | 2006-11-09 | 2011-07-19 | Boston Scientific Scimed, Inc. | Endoprosthesis with coatings |
| DE602007010669D1 (de) * | 2006-12-28 | 2010-12-30 | Boston Scient Ltd | Hren dafür |
| UY30883A1 (es) * | 2007-01-31 | 2008-05-31 | Alcon Res | Tapones punctales y metodos de liberacion de agentes terapeuticos |
| US8070797B2 (en) | 2007-03-01 | 2011-12-06 | Boston Scientific Scimed, Inc. | Medical device with a porous surface for delivery of a therapeutic agent |
| US8431149B2 (en) | 2007-03-01 | 2013-04-30 | Boston Scientific Scimed, Inc. | Coated medical devices for abluminal drug delivery |
| US8067054B2 (en) | 2007-04-05 | 2011-11-29 | Boston Scientific Scimed, Inc. | Stents with ceramic drug reservoir layer and methods of making and using the same |
| US8664290B2 (en) | 2007-04-10 | 2014-03-04 | Zimmer, Inc. | Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications |
| FR2915087B1 (fr) | 2007-04-20 | 2021-11-26 | Corevalve Inc | Implant de traitement d'une valve cardiaque, en particulier d'une valve mitrale, materiel inculant cet implant et materiel de mise en place de cet implant. |
| US7976915B2 (en) * | 2007-05-23 | 2011-07-12 | Boston Scientific Scimed, Inc. | Endoprosthesis with select ceramic morphology |
| US7942926B2 (en) | 2007-07-11 | 2011-05-17 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
| US8002823B2 (en) * | 2007-07-11 | 2011-08-23 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
| WO2009012406A1 (en) | 2007-07-17 | 2009-01-22 | Transcend Medical, Inc. | Ocular implant with hydrogel expansion capabilities reference to priority document |
| US9284409B2 (en) | 2007-07-19 | 2016-03-15 | Boston Scientific Scimed, Inc. | Endoprosthesis having a non-fouling surface |
| US8815273B2 (en) * | 2007-07-27 | 2014-08-26 | Boston Scientific Scimed, Inc. | Drug eluting medical devices having porous layers |
| US7931683B2 (en) | 2007-07-27 | 2011-04-26 | Boston Scientific Scimed, Inc. | Articles having ceramic coated surfaces |
| WO2009018340A2 (en) * | 2007-07-31 | 2009-02-05 | Boston Scientific Scimed, Inc. | Medical device coating by laser cladding |
| WO2009020520A1 (en) * | 2007-08-03 | 2009-02-12 | Boston Scientific Scimed, Inc. | Coating for medical device having increased surface area |
| KR20100058620A (ko) * | 2007-09-07 | 2010-06-03 | 큐엘티 플러그 딜리버리, 인코포레이티드 | 눈물 임플랜트용 삽입 및 적출 기구 |
| CA2698573C (en) * | 2007-09-07 | 2017-12-05 | Qlt Plug Delivery, Inc. | Drug cores for sustained release of therapeutic agents |
| US9011361B2 (en) | 2007-09-07 | 2015-04-21 | Mati Therapeutics Inc. | Lacrimal implant detection |
| NZ583861A (en) | 2007-09-07 | 2012-08-31 | Quadra Logic Tech Inc | Lacrimal implants with an angled intersection between its sections so as to bias a portion of the body against the tissue surface |
| US8052745B2 (en) | 2007-09-13 | 2011-11-08 | Boston Scientific Scimed, Inc. | Endoprosthesis |
| US20090214601A1 (en) * | 2007-09-28 | 2009-08-27 | Chappa Ralph A | Porous Drug Delivery Devices and Related Methods |
| US7938855B2 (en) | 2007-11-02 | 2011-05-10 | Boston Scientific Scimed, Inc. | Deformable underlayer for stent |
| US8029554B2 (en) * | 2007-11-02 | 2011-10-04 | Boston Scientific Scimed, Inc. | Stent with embedded material |
| US20090118809A1 (en) * | 2007-11-02 | 2009-05-07 | Torsten Scheuermann | Endoprosthesis with porous reservoir and non-polymer diffusion layer |
| US8216632B2 (en) | 2007-11-02 | 2012-07-10 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
| US8124601B2 (en) * | 2007-11-21 | 2012-02-28 | Bristol-Myers Squibb Company | Compounds for the treatment of Hepatitis C |
| US20090143855A1 (en) * | 2007-11-29 | 2009-06-04 | Boston Scientific Scimed, Inc. | Medical Device Including Drug-Loaded Fibers |
| WO2009079389A2 (en) * | 2007-12-14 | 2009-06-25 | Boston Scientific Limited | Drug-eluting endoprosthesis |
| EP2222281B1 (de) | 2007-12-20 | 2018-12-05 | Evonik Corporation | Verfahren zur herstellung von mikropartikeln mit geringer restlösemittelmenge |
| US8167787B2 (en) * | 2008-01-03 | 2012-05-01 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
| WO2009091812A2 (en) * | 2008-01-14 | 2009-07-23 | Surmodics, Inc. | Devices and methods for elution of nucleic acid delivery complexes |
| WO2009097468A2 (en) | 2008-01-29 | 2009-08-06 | Kliman Gilbert H | Drug delivery devices, kits and methods therefor |
| JP5528356B2 (ja) * | 2008-02-18 | 2014-06-25 | キュー エル ティー インク. | 涙管インプラントおよび関連する方法 |
| WO2009126830A2 (en) * | 2008-04-09 | 2009-10-15 | Surmodics, Inc. | Delivery of nucleic acid complexes from materials including negatively charged groups |
| EP2265293B1 (de) * | 2008-04-18 | 2015-11-04 | SurModics, Inc. | Beschichtungssysteme zur gesteuerten freisetzung hydrophiler biowirkstoffe |
| JP5581311B2 (ja) | 2008-04-22 | 2014-08-27 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 無機材料のコーティングを有する医療デバイス及びその製造方法 |
| US8932346B2 (en) | 2008-04-24 | 2015-01-13 | Boston Scientific Scimed, Inc. | Medical devices having inorganic particle layers |
| EP2276471B1 (de) | 2008-04-30 | 2018-08-08 | Mati Therapeutics Inc. | Träneneinsatz aus verbundstoff und zugehöriges verfahren |
| EP2296630A2 (de) * | 2008-05-07 | 2011-03-23 | SurModics, Inc. | Abgabe von nukleinsäurekomplexen aus teilchen |
| WO2009137085A2 (en) * | 2008-05-09 | 2009-11-12 | Qlt Plug Delivery, Inc. | Sustained release delivery of active agents to treat glaucoma and ocular hypertension |
| US7998192B2 (en) * | 2008-05-09 | 2011-08-16 | Boston Scientific Scimed, Inc. | Endoprostheses |
| WO2009140197A1 (en) | 2008-05-12 | 2009-11-19 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
| US9439801B2 (en) | 2012-06-29 | 2016-09-13 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US9707122B2 (en) | 2010-07-26 | 2017-07-18 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US8236046B2 (en) | 2008-06-10 | 2012-08-07 | Boston Scientific Scimed, Inc. | Bioerodible endoprosthesis |
| US8449603B2 (en) | 2008-06-18 | 2013-05-28 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
| US20100004733A1 (en) * | 2008-07-02 | 2010-01-07 | Boston Scientific Scimed, Inc. | Implants Including Fractal Structures |
| US8459310B2 (en) * | 2008-07-24 | 2013-06-11 | Surmodics, Inc. | Systems and methods for filling medical device lumen |
| US7985252B2 (en) * | 2008-07-30 | 2011-07-26 | Boston Scientific Scimed, Inc. | Bioerodible endoprosthesis |
| US8382824B2 (en) * | 2008-10-03 | 2013-02-26 | Boston Scientific Scimed, Inc. | Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides |
| EP2352494B1 (de) | 2008-10-30 | 2019-10-09 | Grünenthal GmbH | Neue und potente dosierungsformen von tapentadol |
| US20110125090A1 (en) | 2008-11-13 | 2011-05-26 | Peyman Gholam A | Ophthalmic drug delivery system and method |
| US10842669B2 (en) | 2008-11-13 | 2020-11-24 | Gholam A. Peyman | Ophthalmic drug delivery method |
| US10272035B2 (en) | 2008-11-13 | 2019-04-30 | Gholam A. Peyman | Ophthalmic drug delivery method |
| US20100189765A1 (en) * | 2008-11-26 | 2010-07-29 | Erickson Signe R | Implantable ocular drug delivery device and methods |
| US8231980B2 (en) * | 2008-12-03 | 2012-07-31 | Boston Scientific Scimed, Inc. | Medical implants including iridium oxide |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| CN102365109B (zh) | 2009-01-29 | 2015-06-03 | 弗赛特影像4股份有限公司 | 后段给药 |
| US20100191168A1 (en) | 2009-01-29 | 2010-07-29 | Trustees Of Tufts College | Endovascular cerebrospinal fluid shunt |
| CA2752645C (en) * | 2009-02-23 | 2017-10-03 | Qlt Inc. | Lacrimal implants and related methods |
| WO2010101901A2 (en) * | 2009-03-02 | 2010-09-10 | Boston Scientific Scimed, Inc. | Self-buffering medical implants |
| US8071156B2 (en) * | 2009-03-04 | 2011-12-06 | Boston Scientific Scimed, Inc. | Endoprostheses |
| US20100274352A1 (en) * | 2009-04-24 | 2010-10-28 | Boston Scientific Scrimed, Inc. | Endoprosthesis with Selective Drug Coatings |
| US8287937B2 (en) * | 2009-04-24 | 2012-10-16 | Boston Scientific Scimed, Inc. | Endoprosthese |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| JP5937004B2 (ja) | 2009-05-18 | 2016-06-22 | ドーズ メディカル コーポレーションDose Medical Corporation | 薬剤溶出眼内インプラント |
| WO2012071476A2 (en) | 2010-11-24 | 2012-05-31 | David Haffner | Drug eluting ocular implant |
| US8802121B2 (en) | 2009-06-02 | 2014-08-12 | Surmodics, Inc. | Silane-functionalized hydrophobic α(1→4)glucopyranose polymers and polymeric matrices for implantation or injection |
| CN102596097B (zh) | 2009-06-03 | 2015-05-20 | 弗赛特实验室有限责任公司 | 一种眼插入件 |
| US8586731B2 (en) * | 2009-06-11 | 2013-11-19 | Surmodics, Inc. | Hydrophobic polysaccharides with diester- or carbonate ester-containing linkages having enhanced degradation |
| US20110022158A1 (en) * | 2009-07-22 | 2011-01-27 | Boston Scientific Scimed, Inc. | Bioerodible Medical Implants |
| US9211377B2 (en) | 2009-07-30 | 2015-12-15 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
| RU2545865C2 (ru) * | 2009-09-22 | 2015-04-10 | Евоник Корпорейшн | Имплантируемые устройства с различными вариантами загрузки биологически активного компонента |
| US8932616B2 (en) * | 2009-09-30 | 2015-01-13 | Surmodics, Inc. | Hydrophobic polysaccharides with silyl ether linkages having enhanced degradation and medical articles made therefrom |
| US20110166555A1 (en) * | 2009-09-30 | 2011-07-07 | Jianbo Zhou | Carrier for an insertable medical device, insertion tools, methods of use, and kits |
| US9549842B2 (en) | 2011-02-04 | 2017-01-24 | Joseph E. Kovarik | Buccal bioadhesive strip and method of treating snoring and sleep apnea |
| US8701671B2 (en) | 2011-02-04 | 2014-04-22 | Joseph E. Kovarik | Non-surgical method and system for reducing snoring |
| US8529492B2 (en) | 2009-12-23 | 2013-09-10 | Trascend Medical, Inc. | Drug delivery devices and methods |
| US8568760B2 (en) * | 2009-12-30 | 2013-10-29 | Surmodics, Inc. | Hydrophobic polysaccharides with pendent groups having terminal reactive functionalities and medical uses thereof |
| WO2013022801A1 (en) | 2011-08-05 | 2013-02-14 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
| JP2013521952A (ja) | 2010-03-19 | 2013-06-13 | レベント メディカル インコーポレイテッド | 睡眠時無呼吸の治療システム及び方法 |
| WO2011116382A2 (en) | 2010-03-19 | 2011-09-22 | Revent Medical Inc. | Systems and methods for treatment of sleep apnea |
| US8668732B2 (en) * | 2010-03-23 | 2014-03-11 | Boston Scientific Scimed, Inc. | Surface treated bioerodible metal endoprostheses |
| EP2571464A4 (de) | 2010-05-21 | 2014-08-06 | Revent Medical Inc | Systeme und verfahren zur behandlung von schlafapnoe |
| AU2011285548B2 (en) | 2010-08-05 | 2014-02-06 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
| AU2011285501B2 (en) | 2010-08-05 | 2014-02-27 | Forsight Vision4, Inc. | Implantable therapeutic device |
| LT2600930T (lt) | 2010-08-05 | 2021-04-12 | Forsight Vision4, Inc. | Injekcinis aparatas, skirtas vaisto tiekimui |
| WO2012058274A2 (en) | 2010-10-26 | 2012-05-03 | Surmodics, Inc. | Coatings and methods for controlled elution of hydrophilic active agents |
| EP2640360A2 (de) | 2010-11-19 | 2013-09-25 | Forsight Vision4, Inc. | Therapeutische wirkstoffformulierungen für implantierte vorrichtungen |
| US8901092B2 (en) | 2010-12-29 | 2014-12-02 | Surmodics, Inc. | Functionalized polysaccharides for active agent delivery |
| US12279989B2 (en) | 2011-02-04 | 2025-04-22 | Seed Health, Inc. | Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity |
| US11951140B2 (en) | 2011-02-04 | 2024-04-09 | Seed Health, Inc. | Modulation of an individual's gut microbiome to address osteoporosis and bone disease |
| US12257272B2 (en) | 2015-12-24 | 2025-03-25 | Seed Health, Inc. | Method and system for reducing the likelihood of developing depression in an individual |
| US11844720B2 (en) | 2011-02-04 | 2023-12-19 | Seed Health, Inc. | Method and system to reduce the likelihood of dental caries and halitosis |
| US11951139B2 (en) | 2015-11-30 | 2024-04-09 | Seed Health, Inc. | Method and system for reducing the likelihood of osteoporosis |
| US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
| US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
| EP2726016B1 (de) | 2011-06-28 | 2023-07-19 | ForSight Vision4, Inc. | Vorrichtung zum sammeln einer flüssigkeitsprobe aus einer reservoirkammer einer therapeutischen vorrichtung für das auge |
| CN103889401B (zh) | 2011-08-29 | 2017-10-13 | Qlt公司 | 持续释放递送活性剂以治疗青光眼和高眼压 |
| US9974685B2 (en) | 2011-08-29 | 2018-05-22 | Mati Therapeutics | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
| RU2618194C2 (ru) | 2011-09-14 | 2017-05-02 | Форсайт Вижн5, Инк. | Глазное вкладочное устройство и способы |
| CA2848730A1 (en) * | 2011-09-15 | 2013-03-21 | Yoseph Yaacobi | Systems and methods for treating ear disorders |
| ES2864203T3 (es) | 2011-09-16 | 2021-10-13 | Forsight Vision4 Inc | Aparato de intercambio de fluido |
| US10010448B2 (en) | 2012-02-03 | 2018-07-03 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
| US20150031772A1 (en) * | 2012-02-17 | 2015-01-29 | Bacterin International, Inc. | Adjustable bioactive agent dispersion within a polymeric coating |
| US10085633B2 (en) | 2012-04-19 | 2018-10-02 | Novartis Ag | Direct visualization system for glaucoma treatment |
| US9241832B2 (en) | 2012-04-24 | 2016-01-26 | Transcend Medical, Inc. | Delivery system for ocular implant |
| US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
| MX351261B (es) | 2012-06-01 | 2017-10-06 | Surmodics Inc | Aparato y método para recubrir catéteres con globo. |
| US9827401B2 (en) | 2012-06-01 | 2017-11-28 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
| CN104582635B (zh) * | 2012-08-22 | 2017-06-20 | 加州理工学院 | 用于眼植入体的3线圈的无线功率传输系统 |
| US11090468B2 (en) | 2012-10-25 | 2021-08-17 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
| CN104884006B (zh) | 2012-10-26 | 2017-12-15 | 弗赛特影像5股份有限公司 | 用于持续释放药物到眼睛的眼科系统 |
| WO2014078288A1 (en) | 2012-11-14 | 2014-05-22 | Transcend Medical, Inc. | Flow promoting ocular implant |
| US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
| EP2968113B8 (de) | 2013-03-14 | 2020-10-28 | Forsight Vision4, Inc. | Systeme zur verzögerten intraokularen abgabe schwerlöslicher verbindungen aus einem implantat mit einem portabgabesystem |
| US9526654B2 (en) | 2013-03-28 | 2016-12-27 | Forsight Vision4, Inc. | Ophthalmic implant for delivering therapeutic substances |
| AU2014256955B2 (en) | 2013-04-25 | 2018-02-22 | Innovative Surface Technologies, Inc. | Coatings for controlled release of highly water soluble drugs |
| US12005085B2 (en) | 2013-12-20 | 2024-06-11 | Seed Health, Inc. | Probiotic method and composition for maintaining a healthy vaginal microbiome |
| US11839632B2 (en) | 2013-12-20 | 2023-12-12 | Seed Health, Inc. | Topical application of CRISPR-modified bacteria to treat acne vulgaris |
| US11833177B2 (en) | 2013-12-20 | 2023-12-05 | Seed Health, Inc. | Probiotic to enhance an individual's skin microbiome |
| US11969445B2 (en) | 2013-12-20 | 2024-04-30 | Seed Health, Inc. | Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH |
| US11980643B2 (en) | 2013-12-20 | 2024-05-14 | Seed Health, Inc. | Method and system to modify an individual's gut-brain axis to provide neurocognitive protection |
| US12246043B2 (en) | 2013-12-20 | 2025-03-11 | Seed Health, Inc. | Topical application to treat acne vulgaris |
| US12329783B2 (en) | 2013-12-20 | 2025-06-17 | Seed Health, Inc. | Method and system to improve the health of a person's skin microbiome |
| US11998574B2 (en) | 2013-12-20 | 2024-06-04 | Seed Health, Inc. | Method and system for modulating an individual's skin microbiome |
| US11826388B2 (en) | 2013-12-20 | 2023-11-28 | Seed Health, Inc. | Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation |
| US9737696B2 (en) | 2014-01-15 | 2017-08-22 | Tufts Medical Center, Inc. | Endovascular cerebrospinal fluid shunt |
| JP6637430B2 (ja) | 2014-01-15 | 2020-01-29 | タフツ メディカル センター, インク.Tufts Medical Center, Inc. | 血管内脳脊髄液シャント |
| EP3116941A1 (de) | 2014-03-12 | 2017-01-18 | Zimmer, Inc. | Schmelzstabilisiertes polyethylen mit ultrahohem molekulargewicht und verfahren zu seiner herstellung |
| EP3677229A1 (de) | 2014-05-29 | 2020-07-08 | Glaukos Corporation | Implantate mit funktionen der kontrollierten arzneimittelfreisetzung |
| US10213107B2 (en) * | 2014-07-01 | 2019-02-26 | Injectsense, Inc. | Methods and devices for implantation of intraocular pressure sensors |
| EP3164059B1 (de) | 2014-07-01 | 2023-04-19 | Injectsense, Inc. | Hermetisch abgedichtete implantatsensoren mit senkrechter stapelarchitektur |
| ES2803102T3 (es) | 2014-07-15 | 2021-01-22 | Forsight Vision4 Inc | Dispositivo de administración de implante ocular |
| BR112017002466A2 (pt) | 2014-08-08 | 2017-12-05 | Forsight Vision4 Inc | formulações estáveis e solúveis de inibidores da tirosina cinase do receptor, e métodos para a sua preparação |
| CN114587774B (zh) | 2014-11-10 | 2024-07-19 | 弗赛特影像4股份有限公司 | 治疗眼睛的系统 |
| CN107207741B (zh) | 2014-12-03 | 2021-05-11 | 捷迈有限公司 | 注入抗氧剂的超高分子量聚乙烯 |
| US20160296532A1 (en) | 2015-04-13 | 2016-10-13 | Forsight Vision5, Inc. | Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent |
| JP6812968B2 (ja) * | 2015-05-21 | 2021-01-13 | 東洋製罐グループホールディングス株式会社 | 表面処理金属板及び有機樹脂被覆表面処理金属板 |
| CN108348324B (zh) * | 2015-08-14 | 2020-02-28 | 蒂莫西·R·威利斯 | 人工晶体及相关组件 |
| WO2017040853A1 (en) | 2015-09-02 | 2017-03-09 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
| US11564833B2 (en) | 2015-09-25 | 2023-01-31 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
| CA3005238A1 (en) | 2015-11-20 | 2017-05-26 | Forsight Vision4, Inc. | Porous structures for extended release drug delivery devices |
| WO2017147521A1 (en) | 2016-02-24 | 2017-08-31 | Innovative Surface Technologies, Inc. | Crystallization inhibitor compositions for implantable urological devices |
| US10610669B2 (en) | 2016-03-16 | 2020-04-07 | Krishna Rocha-Singh, M.D. | Apparatus and method for promoting angiogenesis in ischemic tissue |
| US10065018B2 (en) | 2016-03-16 | 2018-09-04 | Krishna Rocha-Singh | Apparatus and method for promoting angiogenesis in ischemic tissue |
| BR112018070383A2 (pt) | 2016-04-05 | 2019-02-05 | Forsight Vision4 Inc | dispositivos para aplicação de fármaco oculares implantáveis |
| EP3442479A1 (de) | 2016-04-20 | 2019-02-20 | Harold Alexander Heitzmann | Vorrichtung zur verabreichung eines bioresorbierbaren okularen medikaments |
| US10543006B2 (en) | 2016-06-09 | 2020-01-28 | Boston Scientific Scimed, Inc. | Infusion catheter |
| EP3522850B1 (de) | 2016-10-05 | 2023-12-27 | Arizona Board of Regents on behalf of the University of Arizona | Verfahren und systeme zur verbesserung der immunsystemreaktionen |
| CA3042709A1 (en) | 2016-11-03 | 2018-08-09 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Stacked tissue encapsulation device systems with or without oxygen delivery |
| AU2017355528B2 (en) | 2016-11-03 | 2021-04-01 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Encapsulation device systems with oxygen sensors with or without exogenous oxygen delivery |
| WO2018144099A1 (en) | 2016-11-03 | 2018-08-09 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods and systems for real-time assessment of cells in encapsulation devices pre-and post-transplantation |
| AU2018372806B2 (en) | 2017-11-21 | 2024-05-30 | Forsight Vision4, Inc. | Fluid exchange apparatus for expandable port delivery system and methods of use |
| KR20210013088A (ko) | 2018-05-24 | 2021-02-03 | 셀라니즈 이브이에이 퍼포먼스 폴리머스 엘엘씨 | 거대 분자 약물 화합물의 지속적인 방출을 위한 이식가능 장치 |
| EP3801378A4 (de) | 2018-05-24 | 2022-02-23 | Celanese EVA Performance Polymers LLC | Implantierbare vorrichtung zur verzögerten freisetzung einer makromolekularen wirkstoffverbindung |
| US11689849B2 (en) | 2018-05-24 | 2023-06-27 | Nureva, Inc. | Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones |
| WO2020112816A1 (en) | 2018-11-29 | 2020-06-04 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
| US11819590B2 (en) | 2019-05-13 | 2023-11-21 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
| US11344526B2 (en) | 2020-03-20 | 2022-05-31 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| US11173291B2 (en) | 2020-03-20 | 2021-11-16 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| US11338119B2 (en) * | 2020-03-20 | 2022-05-24 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| US12115332B2 (en) | 2020-10-30 | 2024-10-15 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods and systems for encapsulation devices for housing cells and agents |
| US11246682B1 (en) * | 2020-11-09 | 2022-02-15 | Elliott Jolley | Systems and methods for providing an orthodontic spring |
| USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
Family Cites Families (225)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US168394A (en) * | 1875-10-05 | Improvement in children s carriages | ||
| US26176A (en) * | 1859-11-22 | Sawmill | ||
| US120174A (en) * | 1871-10-24 | Improvement in feather-renovators | ||
| US21828A (en) * | 1858-10-19 | Perry g | ||
| US47911A (en) * | 1865-05-30 | Improvement in waxed-thread sewing-machines | ||
| US198511A (en) * | 1877-12-25 | Improvement in harness-saddles | ||
| US14036A (en) * | 1856-01-01 | Improvement in grain-binders for harvesters | ||
| US165265A (en) * | 1875-07-06 | Improvement in table-leaf lifters and supporters | ||
| US158598A (en) * | 1875-01-12 | Improvement in culinary vessels | ||
| US32434A (en) * | 1861-05-28 | Improvement in animal-traps | ||
| US114823A (en) * | 1871-05-16 | Improvement in presser-feet for sewing-machines | ||
| US273410A (en) * | 1883-03-06 | Gelatine eye-disk | ||
| US31780A (en) * | 1861-03-26 | Device for forming horseshoes | ||
| US188037A (en) * | 1877-03-06 | Improvement in suspension hooks and clasps | ||
| US22853A (en) * | 1859-02-08 | John l | ||
| US3416530A (en) * | 1966-03-02 | 1968-12-17 | Richard A. Ness | Eyeball medication dispensing tablet |
| US4000745A (en) | 1968-08-05 | 1977-01-04 | Goldberg Edward M | Electrical leads for cardiac stimulators and related methods and means |
| US3625214A (en) | 1970-05-18 | 1971-12-07 | Alza Corp | Drug-delivery device |
| US4069307A (en) * | 1970-10-01 | 1978-01-17 | Alza Corporation | Drug-delivery device comprising certain polymeric materials for controlled release of drug |
| US4144317A (en) * | 1975-05-30 | 1979-03-13 | Alza Corporation | Device consisting of copolymer having acetoxy groups for delivering drugs |
| US4206756A (en) | 1977-03-23 | 1980-06-10 | Murray Grossan | Jet ear irrigation system |
| US4146036A (en) | 1977-10-06 | 1979-03-27 | Medtronic, Inc. | Body-implantable lead with protector for tissue securing means |
| US4292965A (en) | 1978-12-29 | 1981-10-06 | The Population Council, Inc. | Intravaginal ring |
| US4209019A (en) | 1979-01-05 | 1980-06-24 | Medtronic, Inc. | Stylet insertion guide and rotation control device for use with body implantable lead |
| US4300557A (en) | 1980-01-07 | 1981-11-17 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method for treating intraocular malignancies |
| US4304765A (en) * | 1980-10-14 | 1981-12-08 | Alza Corporation | Ocular insert housing steroid in two different therapeutic forms |
| US4678466A (en) | 1981-06-25 | 1987-07-07 | Rosenwald Peter L | Internal medication delivery method and vehicle |
| US5310559A (en) | 1982-09-01 | 1994-05-10 | Hercon Laboratories Corporation | Device for controlled release and delivery to mammalian tissue of pharmacologically active agents incorporating a rate controlling member which comprises an alkylene-alkyl acrylate copolymer |
| US4892736A (en) * | 1983-10-07 | 1990-01-09 | The Forsyth Dental Infirmary For Children | Intra-pocket drug delivery devices for treatment of periodontal diseases |
| US4764377A (en) * | 1983-10-07 | 1988-08-16 | The Forsyth Dental Infirmary For Children | Intra-pocket drug delivery devices for treatment of periodontal diseases |
| GB8527071D0 (en) | 1985-11-04 | 1985-12-11 | Biocompatibles Ltd | Plastics |
| US4959217A (en) | 1986-05-22 | 1990-09-25 | Syntex (U.S.A.) Inc. | Delayed/sustained release of macromolecules |
| US5229128A (en) | 1986-06-11 | 1993-07-20 | Haddad Heskel M | Drug delivery ophthalmic insert and method of preparing same |
| US5322691A (en) * | 1986-10-02 | 1994-06-21 | Sohrab Darougar | Ocular insert with anchoring protrusions |
| US5989579A (en) * | 1986-10-02 | 1999-11-23 | Escalon Medical Corp. | Ocular insert with anchoring protrusions |
| US4863457A (en) | 1986-11-24 | 1989-09-05 | Lee David A | Drug delivery device |
| US5114719A (en) | 1987-04-29 | 1992-05-19 | Sabel Bernhard A | Extended drug delivery of small, water-soluble molecules |
| US4819661A (en) | 1987-10-26 | 1989-04-11 | Cardiac Pacemakers, Inc. | Positive fixation cardiac electrode with drug elution capabilities |
| US4853224A (en) * | 1987-12-22 | 1989-08-01 | Visionex | Biodegradable ocular implants |
| US4997652A (en) | 1987-12-22 | 1991-03-05 | Visionex | Biodegradable ocular implants |
| US4936825A (en) | 1988-04-11 | 1990-06-26 | Ungerleider Bruce A | Method for reducing intraocular pressure caused by glaucoma |
| US5098443A (en) | 1989-03-23 | 1992-03-24 | University Of Miami | Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents |
| US6514238B1 (en) | 1989-08-14 | 2003-02-04 | Photogenesis, Inc. | Method for preparation and transplantation of volute grafts and surgical instrument therefor |
| US4972848A (en) | 1989-08-23 | 1990-11-27 | Medtronic, Inc. | Medical electrical lead with polymeric monolithic controlled release device and method of manufacture |
| US4953564A (en) | 1989-08-23 | 1990-09-04 | Medtronic, Inc. | Screw-in drug eluting lead |
| US5003992A (en) | 1989-08-23 | 1991-04-02 | Holleman Timothy W | Atraumatic screw-in lead |
| US5002067A (en) | 1989-08-23 | 1991-03-26 | Medtronic, Inc. | Medical electrical lead employing improved penetrating electrode |
| US5255693A (en) | 1989-11-02 | 1993-10-26 | Possis Medical, Inc. | Cardiac lead |
| US5525348A (en) | 1989-11-02 | 1996-06-11 | Sts Biopolymers, Inc. | Coating compositions comprising pharmaceutical agents |
| US5164188A (en) | 1989-11-22 | 1992-11-17 | Visionex, Inc. | Biodegradable ocular implants |
| US5545208A (en) | 1990-02-28 | 1996-08-13 | Medtronic, Inc. | Intralumenal drug eluting prosthesis |
| US5076285A (en) | 1990-03-30 | 1991-12-31 | Medtronic, Inc. | Screw-in lead |
| US5120312A (en) * | 1990-04-20 | 1992-06-09 | Regents Of The University Of Minnesota | Method and apparatus for catheterization |
| WO1991017724A1 (en) | 1990-05-17 | 1991-11-28 | Harbor Medical Devices, Inc. | Medical device polymer |
| KR0185215B1 (ko) * | 1990-11-30 | 1999-05-01 | 요시다 쇼오지 | 서방성 안구삽입용 약제 |
| US5378475A (en) * | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
| US5437656A (en) | 1991-02-27 | 1995-08-01 | Leonard Bloom | Method and device for inhibiting H.I.V. hepatitis B and other viruses and germs when using a needle, scalpel and other sharp instrument in a medical environment |
| WO1992015286A1 (en) | 1991-02-27 | 1992-09-17 | Nova Pharmaceutical Corporation | Anti-infective and anti-inflammatory releasing systems for medical devices |
| US5364343A (en) | 1991-03-06 | 1994-11-15 | D.D. S.R.L. | Irrigation device for use in ear canals for therapeutic or hygienic purposes |
| US5221698A (en) | 1991-06-27 | 1993-06-22 | The Regents Of The University Of Michigan | Bioactive composition |
| US5324325A (en) | 1991-06-27 | 1994-06-28 | Siemens Pacesetter, Inc. | Myocardial steroid releasing lead |
| US5681585A (en) | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| US5246867A (en) * | 1992-01-17 | 1993-09-21 | University Of Maryland At Baltimore | Determination and quantification of saccharides by luminescence lifetimes and energy transfer |
| EP0625887B1 (de) | 1992-02-14 | 1998-10-14 | Smith & Nephew, Inc. | Polymere schrauben und beschichtungen zum chirurgischen gebrauch |
| US5599352A (en) | 1992-03-19 | 1997-02-04 | Medtronic, Inc. | Method of making a drug eluting stent |
| US5178635A (en) | 1992-05-04 | 1993-01-12 | Allergan, Inc. | Method for determining amount of medication in an implantable device |
| IT1259100B (it) | 1992-05-20 | 1996-03-11 | Lanfranco Callegaro | Uso di idrogeli per il bloccaggio di sistemi protesici |
| US5447533A (en) | 1992-09-03 | 1995-09-05 | Pacesetter, Inc. | Implantable stimulation lead having an advanceable therapeutic drug delivery system |
| US5314419A (en) | 1992-10-30 | 1994-05-24 | Pelling George E | Method for dispensing ophthalmic drugs to the eye |
| US5449382A (en) | 1992-11-04 | 1995-09-12 | Dayton; Michael P. | Minimally invasive bioactivated endoprosthesis for vessel repair |
| US5578075B1 (en) * | 1992-11-04 | 2000-02-08 | Daynke Res Inc | Minimally invasive bioactivated endoprosthesis for vessel repair |
| EP0604022A1 (de) | 1992-12-22 | 1994-06-29 | Advanced Cardiovascular Systems, Inc. | Mehrschichtiges resorbierbares Stent und Verfahren zu dessen Herstellung |
| US5300108A (en) | 1993-01-05 | 1994-04-05 | Telectronics Pacing Systems, Inc. | Active fixation lead with a dual-pitch, free spinning compound screw |
| US5523092A (en) * | 1993-04-14 | 1996-06-04 | Emory University | Device for local drug delivery and methods for using the same |
| US5464650A (en) | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
| US20020055710A1 (en) | 1998-04-30 | 2002-05-09 | Ronald J. Tuch | Medical device for delivering a therapeutic agent and method of preparation |
| US5673473A (en) * | 1993-06-25 | 1997-10-07 | Medtronic, Inc. | Method of surface finishing a medical device shield using metallic media |
| US20030203976A1 (en) | 1993-07-19 | 2003-10-30 | William L. Hunter | Anti-angiogenic compositions and methods of use |
| US5886026A (en) | 1993-07-19 | 1999-03-23 | Angiotech Pharmaceuticals Inc. | Anti-angiogenic compositions and methods of use |
| KR100389223B1 (ko) | 1993-07-19 | 2003-10-08 | 안지오제네시스 테크놀로지스, 인코포레이티드 | 생체내통로관강을개방유지하기위한스텐트및이의제조방법 |
| US5385148A (en) | 1993-07-30 | 1995-01-31 | The Regents Of The University Of California | Cardiac imaging and ablation catheter |
| US5921982A (en) | 1993-07-30 | 1999-07-13 | Lesh; Michael D. | Systems and methods for ablating body tissue |
| AU7404994A (en) | 1993-07-30 | 1995-02-28 | Regents Of The University Of California, The | Endocardial infusion catheter |
| US5431649A (en) | 1993-08-27 | 1995-07-11 | Medtronic, Inc. | Method and apparatus for R-F ablation |
| US5405376A (en) | 1993-08-27 | 1995-04-11 | Medtronic, Inc. | Method and apparatus for ablation |
| US5807395A (en) | 1993-08-27 | 1998-09-15 | Medtronic, Inc. | Method and apparatus for RF ablation and hyperthermia |
| US5423777A (en) | 1993-10-27 | 1995-06-13 | Tajiri; Akira | Punctum plug |
| US5443505A (en) * | 1993-11-15 | 1995-08-22 | Oculex Pharmaceuticals, Inc. | Biocompatible ocular implants |
| US5849843A (en) | 1993-11-16 | 1998-12-15 | Baxter International Inc. | Polymeric compositions for medical packaging and devices |
| US5466233A (en) * | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same |
| US5472436A (en) | 1994-07-26 | 1995-12-05 | Fremstad; Daria A. | Ocular appliance for delivering medication |
| US5626862A (en) | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
| US5582616A (en) | 1994-08-05 | 1996-12-10 | Origin Medsystems, Inc. | Surgical helical fastener with applicator |
| US5554114A (en) | 1994-10-20 | 1996-09-10 | Micro Therapeutics, Inc. | Infusion device with preformed shape |
| US5725493A (en) | 1994-12-12 | 1998-03-10 | Avery; Robert Logan | Intravitreal medicine delivery |
| US5637113A (en) | 1994-12-13 | 1997-06-10 | Advanced Cardiovascular Systems, Inc. | Polymer film for wrapping a stent structure |
| US5551427A (en) * | 1995-02-13 | 1996-09-03 | Altman; Peter A. | Implantable device for the effective elimination of cardiac arrhythmogenic sites |
| US5605696A (en) | 1995-03-30 | 1997-02-25 | Advanced Cardiovascular Systems, Inc. | Drug loaded polymeric material and method of manufacture |
| US20020091433A1 (en) | 1995-04-19 | 2002-07-11 | Ni Ding | Drug release coated stent |
| US6099562A (en) | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| JPH10506560A (ja) | 1995-04-19 | 1998-06-30 | シュナイダー(ユーエスエー)インク | 薬品を放出する被覆されたステント |
| US6120536A (en) | 1995-04-19 | 2000-09-19 | Schneider (Usa) Inc. | Medical devices with long term non-thrombogenic coatings |
| US5837313A (en) | 1995-04-19 | 1998-11-17 | Schneider (Usa) Inc | Drug release stent coating process |
| IL113723A (en) | 1995-05-14 | 2002-11-10 | Optonol Ltd | Intraocular implant |
| US6117456A (en) | 1995-05-19 | 2000-09-12 | Etex Corporation | Methods and products related to the physical conversion of reactive amorphous calcium phosphate |
| US5609629A (en) | 1995-06-07 | 1997-03-11 | Med Institute, Inc. | Coated implantable medical device |
| US5731087A (en) * | 1995-06-07 | 1998-03-24 | Union Carbide Chemicals & Plastics Technology Corporation | Lubricious coatings containing polymers with vinyl and carboxylic acid moieties |
| US5877224A (en) | 1995-07-28 | 1999-03-02 | Rutgers, The State University Of New Jersey | Polymeric drug formulations |
| US5773019A (en) | 1995-09-27 | 1998-06-30 | The University Of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
| US5810836A (en) | 1996-03-04 | 1998-09-22 | Myocardial Stents, Inc. | Device and method for trans myocardial revascularization (TMR) |
| US5904144A (en) | 1996-03-22 | 1999-05-18 | Cytotherapeutics, Inc. | Method for treating ophthalmic diseases |
| US20030094736A1 (en) | 1996-05-03 | 2003-05-22 | Chuan Qin | Method of surface modifying a medical tubing |
| US6143037A (en) | 1996-06-12 | 2000-11-07 | The Regents Of The University Of Michigan | Compositions and methods for coating medical devices |
| US5928662A (en) | 1996-07-31 | 1999-07-27 | Phillips; Andrew F. | Ocular drug delivery device |
| ZA978537B (en) * | 1996-09-23 | 1998-05-12 | Focal Inc | Polymerizable biodegradable polymers including carbonate or dioxanone linkages. |
| US6053924A (en) | 1996-11-07 | 2000-04-25 | Hussein; Hany | Device and method for trans myocardial revascularization |
| US20030157187A1 (en) | 1996-12-02 | 2003-08-21 | Angiotech Pharmaceuticals, Inc. | Compositions and methods for treating or preventing inflammatory diseases |
| US6495579B1 (en) | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
| US5980972A (en) | 1996-12-20 | 1999-11-09 | Schneider (Usa) Inc | Method of applying drug-release coatings |
| US5997517A (en) | 1997-01-27 | 1999-12-07 | Sts Biopolymers, Inc. | Bonding layers for medical device surface coatings |
| US6547787B1 (en) | 1997-03-13 | 2003-04-15 | Biocardia, Inc. | Drug delivery catheters that attach to tissue and methods for their use |
| US6086582A (en) | 1997-03-13 | 2000-07-11 | Altman; Peter A. | Cardiac drug delivery system |
| DE69835305T2 (de) | 1997-03-31 | 2007-07-19 | Alza Corp., Mountain View | Diffusionsgesteuertes implantierbares Verabreichungssystem |
| EP0980273A1 (de) | 1997-04-16 | 2000-02-23 | White Spot AG | Biodegradables osteosynthese-implantat |
| US6273913B1 (en) | 1997-04-18 | 2001-08-14 | Cordis Corporation | Modified stent useful for delivery of drugs along stent strut |
| US5879697A (en) | 1997-04-30 | 1999-03-09 | Schneider Usa Inc | Drug-releasing coatings for medical devices |
| US6110483A (en) | 1997-06-23 | 2000-08-29 | Sts Biopolymers, Inc. | Adherent, flexible hydrogel and medicated coatings |
| US6306426B1 (en) | 1997-08-11 | 2001-10-23 | Allergan Sales, Inc. | Implant device with a retinoid for improved biocompatibility |
| WO1999007418A2 (en) | 1997-08-11 | 1999-02-18 | Allergan Sales, Inc. | Sterile bioerodible implant device with improved biocompatability and method |
| US6214434B1 (en) * | 1997-09-02 | 2001-04-10 | Seagate Technology Llc | Isolated single-domain high-density magnetic recording media and method of manufacturing the media |
| US5972027A (en) | 1997-09-30 | 1999-10-26 | Scimed Life Systems, Inc | Porous stent drug delivery system |
| US5980548A (en) | 1997-10-29 | 1999-11-09 | Kensey Nash Corporation | Transmyocardial revascularization system |
| US6212434B1 (en) | 1998-07-22 | 2001-04-03 | Cardiac Pacemakers, Inc. | Single pass lead system |
| US6501994B1 (en) | 1997-12-24 | 2002-12-31 | Cardiac Pacemakers, Inc. | High impedance electrode tip |
| US6197324B1 (en) | 1997-12-18 | 2001-03-06 | C. R. Bard, Inc. | System and methods for local delivery of an agent |
| US6251418B1 (en) | 1997-12-18 | 2001-06-26 | C.R. Bard, Inc. | Systems and methods for local delivery of an agent |
| US6221425B1 (en) | 1998-01-30 | 2001-04-24 | Advanced Cardiovascular Systems, Inc. | Lubricious hydrophilic coating for an intracorporeal medical device |
| ES2255155T3 (es) | 1998-02-05 | 2006-06-16 | Biosense Webster, Inc. | Dispositivo para la administracion intracardiaca de farmacos. |
| EP0945148B1 (de) | 1998-03-26 | 2003-11-26 | Biomat B.V. | Endovaskuläre Gefässprothesen mit polymerer Beschichtung |
| US6091978A (en) | 1998-04-07 | 2000-07-18 | Cardiac Pacemakers, Inc. | Removable cap for tissue-insertable connections |
| US20010029351A1 (en) | 1998-04-16 | 2001-10-11 | Robert Falotico | Drug combinations and delivery devices for the prevention and treatment of vascular disease |
| EP1174157B1 (de) | 1998-04-27 | 2005-06-29 | Surmodics Inc. | Bioaktive Wirkstoffe freisetzende Beschichtungen |
| US20020188037A1 (en) * | 1999-04-15 | 2002-12-12 | Chudzik Stephen J. | Method and system for providing bioactive agent release coating |
| US6013099A (en) * | 1998-04-29 | 2000-01-11 | Medtronic, Inc. | Medical device for delivering a water-insoluble therapeutic salt or substance |
| US6306125B1 (en) | 1998-06-22 | 2001-10-23 | Neovasys, Inc. | Angiogenic implant delivery system and method |
| US6153252A (en) * | 1998-06-30 | 2000-11-28 | Ethicon, Inc. | Process for coating stents |
| US6102887A (en) | 1998-08-11 | 2000-08-15 | Biocardia, Inc. | Catheter drug delivery system and method for use |
| US6335029B1 (en) | 1998-08-28 | 2002-01-01 | Scimed Life Systems, Inc. | Polymeric coatings for controlled delivery of active agents |
| US6290728B1 (en) | 1998-09-10 | 2001-09-18 | Percardia, Inc. | Designs for left ventricular conduit |
| US20050147690A1 (en) * | 1998-09-25 | 2005-07-07 | Masters David B. | Biocompatible protein particles, particle devices and methods thereof |
| WO2000018331A2 (en) | 1998-09-29 | 2000-04-06 | C. R. Bard, Inc. | Drug delivery systems |
| US6248112B1 (en) | 1998-09-30 | 2001-06-19 | C. R. Bard, Inc. | Implant delivery system |
| US6399655B1 (en) * | 1998-12-22 | 2002-06-04 | Johns Hopkins University, School Of Medicine | Method for the prophylactic treatment of cataracts |
| US6530950B1 (en) | 1999-01-12 | 2003-03-11 | Quanam Medical Corporation | Intraluminal stent having coaxial polymer member |
| FR2788955B1 (fr) * | 1999-01-28 | 2001-04-06 | Cie Mediterraneenne Des Cafes | Dispositif pour l'extraction de cafe |
| US20040121014A1 (en) | 1999-03-22 | 2004-06-24 | Control Delivery Systems, Inc. | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
| US6217895B1 (en) * | 1999-03-22 | 2001-04-17 | Control Delivery Systems | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
| US6298272B1 (en) | 1999-03-29 | 2001-10-02 | Cardiac Pacemakers, Inc. | High impedance electrode tip with internal drug delivery capability |
| US6719805B1 (en) | 1999-06-09 | 2004-04-13 | C. R. Bard, Inc. | Devices and methods for treating tissue |
| JP2003508185A (ja) | 1999-08-03 | 2003-03-04 | スミス アンド ネフュー インコーポレーテッド | 埋め込み型制御放出装置 |
| US6790228B2 (en) | 1999-12-23 | 2004-09-14 | Advanced Cardiovascular Systems, Inc. | Coating for implantable devices and a method of forming the same |
| US6331313B1 (en) * | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| EP1104681A1 (de) | 1999-12-03 | 2001-06-06 | Biomat B.V. | Draht, Schlauch oder Katheter mit Feuchthaltemittelbeschichtung |
| US6706023B1 (en) | 1999-12-03 | 2004-03-16 | Bionix Development Corporation | Device for irrigation of a blind orifice |
| US6251136B1 (en) | 1999-12-08 | 2001-06-26 | Advanced Cardiovascular Systems, Inc. | Method of layering a three-coated stent using pharmacological and polymeric agents |
| US6360129B1 (en) | 1999-12-13 | 2002-03-19 | Cardiac Pacemakers, Inc. | Mannitol/hydrogel cap for tissue-insertable connections |
| DE60141567D1 (de) * | 2000-01-25 | 2010-04-29 | Edwards Lifesciences Corp | Freisetzungssysteme zur behandlung von restenose und anastomotischer intimaler hyperplasie |
| JP4898993B2 (ja) * | 2000-01-28 | 2012-03-21 | クック メディカル テクノロジーズ エルエルシー | 複数本のワイヤを備えている脈管内医療装置 |
| US6478776B1 (en) | 2000-04-05 | 2002-11-12 | Biocardia, Inc. | Implant delivery catheter system and methods for its use |
| WO2001078626A1 (en) | 2000-04-13 | 2001-10-25 | Sts Biopolymers, Inc. | Targeted therapeutic agent release devices and methods of making and using the same |
| US6638239B1 (en) | 2000-04-14 | 2003-10-28 | Glaukos Corporation | Apparatus and method for treating glaucoma |
| US6375972B1 (en) * | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
| US20020007213A1 (en) | 2000-05-19 | 2002-01-17 | Robert Falotico | Drug/drug delivery systems for the prevention and treatment of vascular disease |
| US20020007215A1 (en) | 2000-05-19 | 2002-01-17 | Robert Falotico | Drug/drug delivery systems for the prevention and treatment of vascular disease |
| US20020005206A1 (en) | 2000-05-19 | 2002-01-17 | Robert Falotico | Antiproliferative drug and delivery device |
| US20020007214A1 (en) | 2000-05-19 | 2002-01-17 | Robert Falotico | Drug/drug delivery systems for the prevention and treatment of vascular disease |
| US6726918B1 (en) | 2000-07-05 | 2004-04-27 | Oculex Pharmaceuticals, Inc. | Methods for treating inflammation-mediated conditions of the eye |
| US6506408B1 (en) * | 2000-07-13 | 2003-01-14 | Scimed Life Systems, Inc. | Implantable or insertable therapeutic agent delivery device |
| US6743233B1 (en) * | 2000-08-02 | 2004-06-01 | Orthopaedic Biosystems, Ltd., Inc. | Medical screw and method of installation |
| US6451373B1 (en) | 2000-08-04 | 2002-09-17 | Advanced Cardiovascular Systems, Inc. | Method of forming a therapeutic coating onto a surface of an implantable prosthesis |
| US6595958B1 (en) | 2000-08-08 | 2003-07-22 | Scimed Life Systems, Inc. | Tortuous path injection device and method |
| US6613017B1 (en) | 2000-08-08 | 2003-09-02 | Scimed Life Systems, Inc. | Controlled depth injection device and method |
| EP1313415B1 (de) | 2000-08-30 | 2008-08-13 | Johns Hopkins University | Vorrichtung zur intraokularen wirkstoffverabreichung |
| US20020111590A1 (en) | 2000-09-29 | 2002-08-15 | Davila Luis A. | Medical devices, drug coatings and methods for maintaining the drug coatings thereon |
| JP5100951B2 (ja) | 2000-09-29 | 2012-12-19 | コーディス・コーポレイション | 被覆医用器具 |
| US20020051730A1 (en) | 2000-09-29 | 2002-05-02 | Stanko Bodnar | Coated medical devices and sterilization thereof |
| EP1330273B1 (de) | 2000-10-31 | 2007-07-25 | Cook Incorporated | Beschichtete, implantierbare medizinische geräte |
| US6545097B2 (en) | 2000-12-12 | 2003-04-08 | Scimed Life Systems, Inc. | Drug delivery compositions and medical devices containing block copolymer |
| US6471980B2 (en) | 2000-12-22 | 2002-10-29 | Avantec Vascular Corporation | Intravascular delivery of mycophenolic acid |
| US7077859B2 (en) | 2000-12-22 | 2006-07-18 | Avantec Vascular Corporation | Apparatus and methods for variably controlled substance delivery from implanted prostheses |
| US6824559B2 (en) | 2000-12-22 | 2004-11-30 | Advanced Cardiovascular Systems, Inc. | Ethylene-carboxyl copolymers as drug delivery matrices |
| US6713081B2 (en) * | 2001-03-15 | 2004-03-30 | The United States Of America As Represented By The Department Of Health And Human Services | Ocular therapeutic agent delivery devices and methods for making and using such devices |
| US20040022853A1 (en) | 2001-04-26 | 2004-02-05 | Control Delivery Systems, Inc. | Polymer-based, sustained release drug delivery system |
| US20020188170A1 (en) | 2001-04-27 | 2002-12-12 | Santamore William P. | Prevention of myocardial infarction induced ventricular expansion and remodeling |
| US7883717B2 (en) | 2001-06-12 | 2011-02-08 | Johns Hopkins University | Reservoir device for intraocular drug delivery |
| US6673453B2 (en) | 2001-06-12 | 2004-01-06 | Biocoat Incorporated | Coatings appropriate for medical devices |
| US7485113B2 (en) | 2001-06-22 | 2009-02-03 | Johns Hopkins University | Method for drug delivery through the vitreous humor |
| US20050129732A1 (en) | 2001-07-13 | 2005-06-16 | Flow Focusing, Inc. | Biodegradable, antibiotic, controlled release tape |
| US20040142013A1 (en) | 2001-07-13 | 2004-07-22 | Flow Focusing, Inc. | Implantable orthopedic surgical devices with controlled release antimicrobial component |
| US6497691B1 (en) | 2001-08-24 | 2002-12-24 | Polymer Group, Inc. | Structurally durable, drapeable breathable barrier film compositions and articles |
| US8303651B1 (en) | 2001-09-07 | 2012-11-06 | Advanced Cardiovascular Systems, Inc. | Polymeric coating for reducing the rate of release of a therapeutic substance from a stent |
| US20030158598A1 (en) | 2001-09-17 | 2003-08-21 | Control Delivery Systems, Inc. | System for sustained-release delivery of anti-inflammatory agents from a coated medical device |
| US6916321B2 (en) | 2001-09-28 | 2005-07-12 | Ethicon, Inc. | Self-tapping resorbable two-piece bone screw |
| US20030097736A1 (en) * | 2001-11-28 | 2003-05-29 | Willis Blankenship | Article securing strap assembly |
| US6764470B2 (en) | 2001-12-03 | 2004-07-20 | Roland P. Dimick | Ear plug medication administration device |
| WO2003071986A2 (en) | 2002-02-22 | 2003-09-04 | Control Delivery Systems, Inc. | Method for treating otic disorders |
| US20030207856A1 (en) | 2002-03-18 | 2003-11-06 | Patrice Tremble | Medical devices and compositions for delivering anti-proliferatives to anatomical sites at risk for restenosis |
| AU2003241515A1 (en) | 2002-05-20 | 2003-12-12 | Orbus Medical Technologies Inc. | Drug eluting implantable medical device |
| US20040138695A1 (en) | 2002-06-18 | 2004-07-15 | Shu-Tung Li | Coatings of implants |
| US20030232087A1 (en) | 2002-06-18 | 2003-12-18 | Lawin Laurie R. | Bioactive agent release coating with aromatic poly(meth)acrylates |
| US7097850B2 (en) | 2002-06-18 | 2006-08-29 | Surmodics, Inc. | Bioactive agent release coating and controlled humidity method |
| US20030236513A1 (en) | 2002-06-19 | 2003-12-25 | Scimed Life Systems, Inc. | Implantable or insertable medical devices for controlled delivery of a therapeutic agent |
| US7939094B2 (en) | 2002-06-19 | 2011-05-10 | Boston Scientific Scimed, Inc. | Multiphase polymeric drug release region |
| US8211455B2 (en) | 2002-06-19 | 2012-07-03 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices for controlled delivery of a therapeutic agent |
| US7169162B2 (en) | 2002-07-03 | 2007-01-30 | Orbusneich Medical, Inc. | Balloon catheter |
| US20040006146A1 (en) | 2002-07-06 | 2004-01-08 | Evans Douglas G. | Resorbable structure for treating and healing of tissue defects |
| WO2004014447A1 (en) | 2002-08-13 | 2004-02-19 | Medtronic, Inc. | Active agent delivery system including a poly(ethylene-co-(meth)acrylate), medical device, and method |
| US6731087B1 (en) * | 2002-08-19 | 2004-05-04 | Huang Chin-Cheng | Fan motor |
| JP3642063B2 (ja) * | 2002-08-22 | 2005-04-27 | 株式会社村田製作所 | テルビウム・アルミニウム系常磁性ガーネット単結晶の製造方法 |
| US7438925B2 (en) * | 2002-08-26 | 2008-10-21 | Biovention Holdings Ltd. | Drug eluting coatings for medical implants |
| CA2689424A1 (en) | 2002-09-29 | 2004-04-08 | Surmodics, Inc. | Methods for treatment and/or prevention of retinal disease |
| US7103418B2 (en) | 2002-10-02 | 2006-09-05 | Medtronic, Inc. | Active fluid delivery catheter |
| US20040137059A1 (en) | 2003-01-09 | 2004-07-15 | Thierry Nivaggioli | Biodegradable ocular implant |
| ATE476960T1 (de) | 2003-05-02 | 2010-08-15 | Surmodics Inc | System zur kontrollierten freisetzung eines bioaktiven wirkstoffs im hinteren bereich des auges |
| US7654997B2 (en) | 2004-04-21 | 2010-02-02 | Acclarent, Inc. | Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat |
-
2004
- 2004-04-29 AT AT05025475T patent/ATE476960T1/de not_active IP Right Cessation
- 2004-04-29 WO PCT/US2004/013327 patent/WO2004098565A2/en active Application Filing
- 2004-04-29 US US10/835,530 patent/US8021680B2/en not_active Expired - Fee Related
- 2004-04-29 EP EP04750957A patent/EP1633320A2/de not_active Withdrawn
- 2004-04-29 AU AU2004237774A patent/AU2004237774B2/en not_active Ceased
- 2004-04-29 CA CA2524271A patent/CA2524271C/en not_active Expired - Fee Related
- 2004-04-29 DE DE602004028638T patent/DE602004028638D1/de not_active Expired - Lifetime
- 2004-04-29 JP JP2006513459A patent/JP4824549B2/ja not_active Expired - Fee Related
-
2005
- 2005-08-15 US US11/204,195 patent/US20050276837A1/en not_active Abandoned
- 2005-08-15 US US11/204,271 patent/US20050271706A1/en not_active Abandoned
- 2005-08-15 US US11/203,879 patent/US7976862B2/en not_active Expired - Fee Related
- 2005-08-15 US US11/203,931 patent/US20050281863A1/en not_active Abandoned
- 2005-08-15 US US11/203,981 patent/US7824704B2/en not_active Expired - Fee Related
- 2005-09-12 US US11/225,301 patent/US8034369B2/en not_active Expired - Fee Related
- 2005-12-15 JP JP2005361934A patent/JP4897287B2/ja not_active Expired - Fee Related
-
2011
- 2011-05-24 JP JP2011116262A patent/JP5174213B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20050271706A1 (en) | 2005-12-08 |
| DE602004028638D1 (de) | 2010-09-23 |
| US7824704B2 (en) | 2010-11-02 |
| JP2006525091A (ja) | 2006-11-09 |
| EP1633320A2 (de) | 2006-03-15 |
| AU2004237774B2 (en) | 2009-09-10 |
| JP4824549B2 (ja) | 2011-11-30 |
| US7976862B2 (en) | 2011-07-12 |
| CA2524271A1 (en) | 2004-11-18 |
| JP2006312015A (ja) | 2006-11-16 |
| US20060013835A1 (en) | 2006-01-19 |
| JP2011167551A (ja) | 2011-09-01 |
| US20050019371A1 (en) | 2005-01-27 |
| WO2004098565A3 (en) | 2005-03-03 |
| WO2004098565A2 (en) | 2004-11-18 |
| US8034369B2 (en) | 2011-10-11 |
| JP4897287B2 (ja) | 2012-03-14 |
| US20050276837A1 (en) | 2005-12-15 |
| US20050271703A1 (en) | 2005-12-08 |
| JP5174213B2 (ja) | 2013-04-03 |
| US20050287188A1 (en) | 2005-12-29 |
| AU2004237774A1 (en) | 2004-11-18 |
| CA2524271C (en) | 2012-09-04 |
| US20050281863A1 (en) | 2005-12-22 |
| US8021680B2 (en) | 2011-09-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE476960T1 (de) | System zur kontrollierten freisetzung eines bioaktiven wirkstoffs im hinteren bereich des auges | |
| WO2008027371A3 (en) | Low profile bioactive agent delivery device | |
| AU2002320611A1 (en) | Catheter for modification of agent formulation | |
| ATE434419T1 (de) | Flexibles embolie-vorrichtung-abgabesystem | |
| WO2008124482A3 (en) | Apparatus and method for treatment of ethmoids | |
| EP2845621A3 (de) | Implantierbare Vorrichtungen zur Abgabe von Arzneimitteln und anderen Substanzen zur Behandlung von Sinusitis und anderen Erkrankungen | |
| EP1832251A3 (de) | Vorrichtung zur Behandlung eines verzweigten Bereichs einer Röhre und Verfahren zur Platzierung einer medizinischen Vorrichtung in einer verzweigten Röhre | |
| DE602007007202D1 (de) | Mikrokathetervorrichtungen und verfahren für gezielte wirkstofffreisetzung | |
| WO2010074705A3 (en) | Needleless injection device components, systems, and methods | |
| EP1982695A3 (de) | Herstellung von Vorrichtungen zur Langzeitarzneimittelversorgung mit Polyurethan | |
| WO2008011125A3 (en) | Devices, systems and methods for ophthalmic drug delivery | |
| WO2010039641A3 (en) | Long term drug delivery devices with polyurethane-based polymers and their manufacture | |
| ATE404125T1 (de) | Ausrichtungsteil zur verabreichung eines unsysmetrischen geräts mit einer vorbestimmten ausrichtung | |
| WO2003082188A3 (en) | Methods and drug delivery systems for the treatment of orofacial diseases | |
| DE602004029155D1 (de) | Dilatations- und stentablagesystem | |
| ATE553793T1 (de) | Medizinische vorrichtung zur abgabe eines biologisch wirksamen materials | |
| TW200700094A (en) | Coated microprojections having reduced variability and method for producing same | |
| WO2006002366A3 (en) | Biodegradable ocular devices, methods and systems | |
| WO2009076547A8 (en) | Implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens | |
| WO2010001325A3 (en) | Methods, compositions and systems for local delivery of drugs | |
| EP4275623A3 (de) | Abnehmbare implantierbare vorrichtungen | |
| DE602006019192D1 (de) | Vorrichtung und System zur Abgabe eines härtbaren Materials in einen Knochen | |
| WO2004073500A3 (en) | Bone access system | |
| DE60235775D1 (de) | Intraluminale Vorrichtung mit einer therapeutisches-mittel enthaltenden Beschichtung | |
| EP1987777A3 (de) | System und Verfahren zur Behandlung von Septumschäden |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |