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AU2223495A - Spiro compound and medicinal composition thereof - Google Patents

Spiro compound and medicinal composition thereof

Info

Publication number
AU2223495A
AU2223495A AU22234/95A AU2223495A AU2223495A AU 2223495 A AU2223495 A AU 2223495A AU 22234/95 A AU22234/95 A AU 22234/95A AU 2223495 A AU2223495 A AU 2223495A AU 2223495 A AU2223495 A AU 2223495A
Authority
AU
Australia
Prior art keywords
medicinal composition
spiro compound
spiro
compound
medicinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU22234/95A
Inventor
Masahiro Fujii
Ken Ikeda
Yasuo Isomura
Akio Kakefuda
Hirokazu Kubota
Hitoshi Nagaoka
Yoshinori Okamoto
Osamu Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of AU2223495A publication Critical patent/AU2223495A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU22234/95A 1994-04-15 1995-04-12 Spiro compound and medicinal composition thereof Abandoned AU2223495A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP6-101936 1994-04-15
JP10193694 1994-04-15
JP6-255382 1994-10-20
JP25538294 1994-10-20
PCT/JP1995/000713 WO1995028389A1 (en) 1994-04-15 1995-04-12 Spiro compound and medicinal composition thereof

Publications (1)

Publication Number Publication Date
AU2223495A true AU2223495A (en) 1995-11-10

Family

ID=26442705

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22234/95A Abandoned AU2223495A (en) 1994-04-15 1995-04-12 Spiro compound and medicinal composition thereof

Country Status (2)

Country Link
AU (1) AU2223495A (en)
WO (1) WO1995028389A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2135494C1 (en) 1995-12-01 1999-08-27 Санкио Компани Лимитед Heterocyclic compounds and composition on said showing antagonistic effect with respect to tachykinin receptors
JP3017147B2 (en) 1996-11-08 2000-03-06 三共株式会社 Optically active sulfoxide derivative
JP3192631B2 (en) 1997-05-28 2001-07-30 三共株式会社 Pharmaceuticals consisting of saturated heterocyclic compounds
ID23697A (en) 1997-05-30 2000-05-11 Sankyo Co SALT FROM OPTIMUM SULFOXIDE
AU9810598A (en) * 1997-10-27 1999-05-17 Schering Corporation Optically active intermediates for the preparation of optically active substituted oximes, hydrazones and olefins useful as neurokinin antagonists
US6265614B1 (en) 1997-10-27 2001-07-24 Schering Corporation Optically active intermediates for the preparation of optically active substituted oximes, hydrazones and olefins useful as neurokinin antagonists
WO1999028307A1 (en) * 1997-12-04 1999-06-10 Sankyo Company, Limited Alicyclic acylated heterocyclic derivatives
EP1695977A3 (en) * 2000-12-12 2006-09-20 Neurogen Corporation Spiro [isobenzofuran-1,4'piperidin]-3-ones and 3H-spiroisobenzofuran-1, 4'-piperidines
EP1347982B1 (en) * 2000-12-12 2005-11-16 Neurogen Corporation Spiro isobenzofuran-1,4'-piperidin]-3-ones and 3h-spiroisobenzofuran-1,4'-piperidines
EP1373247A2 (en) * 2001-03-29 2004-01-02 Tanabe Seiyaku Co., Ltd. Spiroisoquinoline compounds, methods for their preparation and intermediates thereof
US20030078278A1 (en) * 2001-06-26 2003-04-24 Pfizer Inc. Spiropiperidine compounds as ligands for ORL-1 receptor
US7396930B2 (en) 2002-06-11 2008-07-08 Sankyo Company, Limited Process for producing cyclic thioether and synthetic intermediate thereof
AU2003296992A1 (en) * 2002-12-13 2004-07-09 Smithkline Beecham Corporation Pyrrolidine and azetidine compounds as ccr5 antagonists
US7879834B2 (en) 2004-08-19 2011-02-01 Vertex Pharmaceuticals Incorporated Spiroindoline modulators of muscarinic receptors
US7786141B2 (en) 2004-08-19 2010-08-31 Vertex Pharmaceuticals Incorporated Dihydrospiroindene modulators of muscarinic receptors
AU2005309365B2 (en) 2004-11-29 2011-10-06 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
JP4769464B2 (en) * 2005-01-12 2011-09-07 広栄化学工業株式会社 Method for producing alcohol compound
AU2006312557B2 (en) 2005-11-10 2011-12-08 Msd K.K. Aza-substituted spiro derivative
WO2007076070A2 (en) 2005-12-22 2007-07-05 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
ATE517106T1 (en) 2006-02-22 2011-08-15 Vertex Pharma CONDENSED SPIROPIPERIDINE AS MODULATORS OF MUSCARINOUS RECEPTORS
JP2009527568A (en) 2006-02-22 2009-07-30 バーテックス ファーマシューティカルズ インコーポレイテッド Modulator of muscarinic receptor
JP2009542670A (en) 2006-06-29 2009-12-03 バーテックス ファーマシューティカルズ インコーポレイテッド Modulator of muscarinic receptor
CA2660903A1 (en) 2006-08-15 2008-02-21 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
US7786107B2 (en) 2006-08-18 2010-08-31 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
CN101641099A (en) 2007-01-24 2010-02-03 葛兰素集团有限公司 Pharmaceutical compositions comprising 3, 5-diamin0-6- (2, 3-dichl0phenyl) -l, 2, 4-triazine or r (-) -2, 4-diamino-5- (2, 3-dichlorophenyl) -6-fluoromethyl pyrimidine and an nk1
WO2009045519A1 (en) 2007-10-03 2009-04-09 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
CN106866667B (en) 2009-11-05 2019-11-15 圣母大学 Imidazo [1,2-a] pyridine compounds and their and its synthesis and application method
EP3221314B1 (en) * 2014-11-21 2019-07-03 Esteve Pharmaceuticals, S.A. Spiro-isoquinoline-1,4'-piperidine compounds having multimodal activity against pain
CN108348510B (en) 2015-09-17 2022-01-04 圣母大学 Benzylamine-containing heterocyclic compounds and compositions useful against mycobacterial infections

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962259A (en) * 1973-12-12 1976-06-08 American Hoechst Corporation 1,3-Dihydrospiro[isobenzofuran]s and derivatives thereof
ES468860A1 (en) * 1977-04-21 1979-09-16 Hoechst Ag Spiro(indoline-3,4'-piperidine)s and related compounds
JPS55143980A (en) * 1979-04-27 1980-11-10 Dai Ichi Seiyaku Co Ltd Anti-allergic preparation
GB8917069D0 (en) * 1989-07-26 1989-09-13 Merck Sharp & Dohme Therapeutic agents
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
WO1995028389A1 (en) 1995-10-26

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